Long noncoding RNA NEAT1 promotes cardiac fibrosis in heart failure through increased recruitment of EZH2 to the Smad7 promoter region

Downregulated microRNA-129-5p by Long Non-coding RNA NEAT1 Upregulates PEG3 Expression to Aggravate Non-alcoholic Steatohepatitis

(2021) Zhi Zhang et al.   Frontiers in Genetics

LncRNA Neat1 expedites the progression of liver fibrosis in mice through targeting miR-148a-3p and miR-22-3p to upregulate Cyth3

(2021) Wei Huang et al.   CELL CYCLE

LncRNA NEAT1 inhibition upregulates miR-16-5p to restrain the progression of sepsis-induced lung injury via suppressing BRD4 in a mouse model

(2021) Jianhong Yin et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Differential Expression of SMAD Genes and S1PR1 on Circulating CD4+ T Cells in Multiple Sclerosis and Crohn’s Disease

(2020) Judith Abarca-Zabalía et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

EZH2 deficiency attenuates Treg differentiation in rheumatoid arthritis

(2020) Xin-yue Xiao et al.   JOURNAL OF AUTOIMMUNITY

Long non-coding RNA NEAT1 promotes colorectal cancer progression by regulating miR-205-5p/VEGFA axis

(2020) Huijie Liu et al.   Human Cell

LncRNA GAS5 attenuates fibroblast activation through inhibiting Smad3 signaling

(2020) Rui Tang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Long noncoding RNA NEAT1 suppresses hepatocyte proliferation in fulminant hepatic failure through increased recruitment of EZH2 to the LATS2 promoter region and promotion of H3K27me3 methylation

(2020) Qiang Wang et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

GSK343, an inhibitor of EZH2, mitigates fibrosis and inflammation mediated by HIF-1α in human peritoneal mesothelial cells treated with high glucose

(2020) Qinglian Wang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Nanoparticles (NPs)‐Meditated LncRNA AFAP1‐AS1 Silencing to Block Wnt/ β ‐Catenin Signaling Pathway for Synergistic Reversal of Radioresistance and Effective Cancer Radiotherapy

(2020) Zhuofei Bi et al.   Advanced Science

LncSEA: a platform for long non-coding RNA related sets and enrichment analysis

(2020) Jiaxin Chen et al.   NUCLEIC ACIDS RESEARCH

Emodin ameliorates tubulointerstitial fibrosis in obstructed kidneys by inhibiting EZH2

(2020) Lin Xu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Investigation of hub genes and immune status in heart transplant rejection using endomyocardial biopsies

(2020) Meng‐xi Xiu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Inhibition of EZH2 prevents fibrosis and restores normal angiogenesis in scleroderma

(2019) Pei-Suen Tsou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A lncRNA Links TGF-β Signaling in Lung Fibrosis

(2019) Dianhua Jiang et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Long noncoding RNA Neat1 modulates myogenesis by recruiting Ezh2

(2019) Shanshan Wang et al.   Cell Death & Disease

ZNNT1 long noncoding RNA induces autophagy to inhibit tumorigenesis of uveal melanoma by regulating key autophagy gene expression

(2019) Peng Li et al.   Autophagy

BAOXIN Granules Protected Mouse Model With Elevated Afterload From Cardiac Hypertrophy by Suppressing Both Inflammatory Reaction and Collagen Deposition

(2019) Xu Qiu et al.   Frontiers in Physiology

EZH2 as a novel therapeutic target for atrial fibrosis and atrial fibrillation

(2019) Shuai Song et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling

(2019) Huimei Chen et al.   Nature Communications

Bone Morphogenetic Protein 9 Reduces Cardiac Fibrosis and Improves Cardiac Function in Heart Failure

(2018) Kevin J. Morine et al.   CIRCULATION

Long non-coding RNA NEAT1-modulated abnormal lipolysis via ATGL drives hepatocellular carcinoma proliferation

(2018) Xirui Liu et al.   Molecular Cancer

Long Noncoding RNA NEAT1 Promotes Growth and Metastasis of Cholangiocarcinoma Cells

(2018) Cheng Zhang et al.   ONCOLOGY RESEARCH

Knockdown of long non-coding RNA NEAT1 inhibits glioma cell migration and invasion via modulation of SOX2 targeted by miR-132

(2018) Ke Zhou et al.   Molecular Cancer

BMI1 promotes cardiac fibrosis in ischemia-induced heart failure via the PTEN-PI3K/Akt-mTOR signaling pathway

(2018) Wenbo Yang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Long non-coding RNA NEAT1 promotes colorectal cancer progression by competitively binding miR-34a with SIRT1 and enhancing the Wnt/β-catenin signaling pathway

(2018) Yang Luo et al.   CANCER LETTERS

Fibroblast-specific TGF-β–Smad2/3 signaling underlies cardiac fibrosis

(2017) Hadi Khalil et al.   JOURNAL OF CLINICAL INVESTIGATION

NEAT1 accelerates the progression of liver fibrosis via regulation of microRNA-122 and Kruppel-like factor 6

(2017) Fujun Yu et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

The long noncoding RNA Wisper controls cardiac fibrosis and remodeling

(2017) Rudi Micheletti et al.   Science Translational Medicine

Loss of β-catenin in resident cardiac fibroblasts attenuates fibrosis induced by pressure overload in mice

(2017) Fu-Li Xiang et al.   Nature Communications

Changes of myocardial gene expression and protein composition in patients with dilated cardiomyopathy after immunoadsorption with subsequent immunoglobulin substitution

(2016) Sabine Ameling et al.   BASIC RESEARCH IN CARDIOLOGY

Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression

(2016) Matthias Eden et al.   Nature Communications

Targeting EZH1 and EZH2 contributes to the suppression of fibrosis-associated genes by miR-214-3p in cardiac myofibroblasts

(2016) Wen-Si Zhu et al.   Oncotarget

Long noncoding RNAs expressed in human hepatic stellate cells form networks with extracellular matrix proteins

(2016) Chan Zhou et al.   Genome Medicine

Upregulation and Clinicopathological Significance of Long Non-coding NEAT1 RNA in NSCLC Tissues

(2015) Lin-Jiang Pan et al.   Asian Pacific Journal of Cancer Prevention

TSC-22 up-regulates collagen 3a1 gene expression in the rat heart

(2015) Annina Kelloniemi et al.   BMC Cardiovascular Disorders

Lineage and species-specific long noncoding RNAs during erythro-megakaryocytic development

(2014) V. R. Paralkar et al.   BLOOD

Human colorectal cancer-specific CCAT1-L lncRNA regulates long-range chromatin interactions at the MYC locus

(2014) Jian-Feng Xiang et al.   CELL RESEARCH

The Long Noncoding RNAs NEAT1 and MALAT1 Bind Active Chromatin Sites

(2014) Jason A. West et al.   MOLECULAR CELL

An individual patient meta-analysis of five randomized trials assessing the effects of cardiac resynchronization therapy on morbidity and mortality in patients with symptomatic heart failure

(2013) J. G. Cleland et al.   EUROPEAN HEART JOURNAL

Re: Long Non-Coding RNA H19 Increases Bladder Cancer Metastasis by Associating with EZH2 and Inhibiting E-Cadherin Expression

(2013) Anthony Atala   JOURNAL OF UROLOGY

Long noncoding RNA high expression in hepatocellular carcinoma facilitates tumor growth through enhancer of zeste homolog 2 in humans

(2011) Fu Yang et al.   HEPATOLOGY

TSC-22 Promotes Transforming Growth Factor  -Mediated Cardiac Myofibroblast Differentiation by Antagonizing Smad7 Activity

(2011) X. Yan et al.   MOLECULAR AND CELLULAR BIOLOGY

Molecular Mechanisms of Long Noncoding RNAs

(2011) Kevin C. Wang et al.   MOLECULAR CELL

Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes

(2010) M.-C. Tsai et al.   SCIENCE