Mechanistic Insight into Metal Ion-Catalyzed Transamination

A hydrogen-dependent geochemical analogue of primordial carbon and energy metabolism

(2020) Martina Preiner et al.   Nature Ecology & Evolution

Nonenzymatic Metabolic Reactions and Life’s Origins

(2020) Kamila B. Muchowska et al.   CHEMICAL REVIEWS

A plausible metal-free ancestral analogue of the Krebs cycle composed entirely of α-ketoacids

(2020) R. Trent Stubbs et al.   Nature Chemistry

Synthesis and breakdown of universal metabolic precursors promoted by iron

(2019) Kamila B. Muchowska et al.   NATURE

Carbonyl catalysis enables a biomimetic asymmetric Mannich reaction

(2018) Jianfeng Chen et al.   SCIENCE

Native iron reduces CO2 to intermediates and end-products of the acetyl-CoA pathway

(2018) Sreejith J. Varma et al.   Nature Ecology & Evolution

An appeal to magic? The discovery of a non-enzymatic metabolism and its role in the origins of life

(2018) Markus Ralser   BIOCHEMICAL JOURNAL

Investigating Glyoxylate-Mediated Transamination Using Dipeptide Arrays and Proteomic Peptide Mixtures

(2018) Xiaohong Tan et al.   BIOCONJUGATE CHEMISTRY

Reaction of glycine with glyoxylate: Competing transaminations, aldol reactions, and decarboxylations

(2017) Mark Conley et al.   JOURNAL OF PHYSICAL ORGANIC CHEMISTRY

Nonenzymatic gluconeogenesis-like formation of fructose 1,6-bisphosphate in ice

(2017) Christoph B. Messner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metals promote sequences of the reverse Krebs cycle

(2017) Kamila B. Muchowska et al.   Nature Ecology & Evolution

Enzyme-Inspired Axially Chiral Pyridoxamines Armed with a Cooperative Lateral Amine Chain for Enantioselective Biomimetic Transamination

(2016) Yong Ethan Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

MN15: A Kohn–Sham global-hybrid exchange–correlation density functional with broad accuracy for multi-reference and single-reference systems and noncovalent interactions

(2016) Haoyu S. Yu et al.   Chemical Science

Conditional iron and pH-dependent activity of a non-enzymatic glycolysis and pentose phosphate pathway

(2016) M. A. Keller et al.   Science Advances

Progress in asymmetric biomimetic transamination of carbonyl compounds

(2015) Ying Xie et al.   CHEMICAL SOCIETY REVIEWS

Chiral Pyridoxal-Catalyzed Asymmetric Biomimetic Transamination of α-Keto Acids

(2015) Limin Shi et al.   ORGANIC LETTERS

Non-enzymatic glycolysis and pentose phosphate pathway-like reactions in a plausible Archean ocean

(2014) M. A. Keller et al.   Molecular Systems Biology

A comparative DFT study of the Schiff base formation from acetaldehyde and butylamine, glycine and phosphatidylethanolamine

(2012) Christian Solís-Calero et al.   THEORETICAL CHEMISTRY ACCOUNTS

Substituent Effects on Electrophilic Catalysis by the Carbonyl Group: Anatomy of the Rate Acceleration for PLP-Catalyzed Deprotonation of Glycine

(2011) Juan Crugeiras et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic Asymmetric Biomimetic Transamination: From α-Keto Esters to Optically Active α-Amino Acid Derivatives

(2011) Xiao Xiao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dendrimers in solution can have their remote catalytic groups folded back into the core: Enantioselective transaminations by dendritic enzyme mimics-II

(2009) Sujun Wei et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Universal Solvation Model Based on Solute Electron Density and on a Continuum Model of the Solvent Defined by the Bulk Dielectric Constant and Atomic Surface Tensions

(2009) Aleksandr V. Marenich et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Substituent Effects on the Thermodynamic Stability of Imines Formed from Glycine and Aromatic Aldehydes: Implications for the Catalytic Activity of Pyridoxal-5′-phosphate

(2009) Juan Crugeiras et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Glycine Enolates:  The Effect of Formation of Iminium Ions to Simple Ketones on α-Amino Carbon Acidity and a Comparison with Pyridoxal Iminium Ions

(2008) Juan Crugeiras et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY