Physiologically Based Pharmacokinetic Modeling of 3 HIV Drugs in Combination and the Role of Lymphatic System after Subcutaneous Dosing. Part 2: Model for the Drug-combination Nanoparticles

A Qualitative Exploration of Women's Interest in Long-Acting Injectable Antiretroviral Therapy Across Six Cities in the Women's Interagency HIV Study: Intersections with Current and Past Injectable Medication and Substance Use

(2021) Morgan M. Philbin et al.   AIDS PATIENT CARE AND STDS

CROI 2021

(2021) Farooq Kazi et al.   LANCET INFECTIOUS DISEASES

Highlights of virtual CROI 2021

(2021) Peter Hayward   Lancet HIV

Controlled solvent removal from antiviral drugs and excipients in solution enables the formation of novel combination multi-drug-motifs in pharmaceutical powders composed of lopinavir, ritonavir and tenofovir

(2020) Jesse Yu et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Novel Long-Acting Drug Combination Nanoparticles Composed of Gemcitabine and Paclitaxel Enhance Localization of Both Drugs in Metastatic Breast Cancer Nodules

(2020) Jesse Yu et al.   PHARMACEUTICAL RESEARCH

Long-acting drugs and formulations for the treatment and prevention of HIV infection

(2020) Charles Flexner et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Systems and Clinical Pharmacology of COVID-19 Therapeutic Candidates: A Clinical and Translational Medicine Perspective

(2020) Simone Perazzolo et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Long-acting implants to treat and prevent HIV infection

(2019) Ethel D. Weld et al.   Current Opinion in HIV and AIDS

High-resolution 3D imaging and topological mapping of the lymph node conduit system

(2019) Inken D. Kelch et al.   PLOS BIOLOGY

Addressing the global burden of hepatitis B virus while developing long-acting injectables for the prevention and treatment of HIV

(2019) Robert C Bollinger et al.   Lancet HIV

Mechanism-based pharmacokinetic (MBPK) models describe the complex plasma kinetics of three antiretrovirals delivered by a long-acting anti-HIV drug combination nanoparticle formulation

(2018) John C. Kraft et al.   JOURNAL OF CONTROLLED RELEASE

Indocyanine green nanoparticles undergo selective lymphatic uptake, distribution and retention and enable detailed mapping of lymph vessels, nodes and abnormalities

(2018) John C. Kraft et al.   JOURNAL OF DRUG TARGETING

Extended cell and plasma drug levels after one dose of a 3-in-1 nanosuspension containing lopinavir, efavirenz, and tenofovir in non-human primates

(2018) Josefin Koehn et al.   AIDS

T Cell Trafficking through Lymphatic Vessels

(2016) Morgan C. Hunter et al.   Frontiers in Immunology

A Bottom-Up Whole-Body Physiologically Based Pharmacokinetic Model to Mechanistically Predict Tissue Distribution and the Rate of Subcutaneous Absorption of Therapeutic Proteins

(2015) Katherine L. Gill et al.   AAPS Journal

Anti-HIV Drug-Combination Nanoparticles Enhance Plasma Drug Exposure Duration as Well as Triple-Drug Combination Levels in Cells Within Lymph Nodes and Blood in Primates

(2015) Jennifer P. Freeling et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Novel Liquid Chromatography-Tandem Mass Spectrometry Method for Simultaneous Detection of Anti-HIV Drugs Lopinavir, Ritonavir, and Tenofovir in Plasma

(2014) J. Koehn et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mathematical Modeling Reveals Kinetics of Lymphocyte Recirculation in the Whole Organism

(2014) Vitaly V. Ganusov et al.   PLoS Computational Biology

Dermal Clearance Model for Epidermal Bioavailability Calculations

(2012) Rania Ibrahim et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Lymph node homing of T cells and dendritic cells via afferent lymphatics

(2012) Reinhold Förster et al.   TRENDS IN IMMUNOLOGY

Novel Gd Nanoparticles Enhance Vascular Contrast for High-Resolution Magnetic Resonance Imaging

(2010) Tot Bui et al.   PLoS One

Noninvasive in vivo imaging of CD4 cells in simian-human immunodeficiency virus (SHIV)-infected nonhuman primates

(2009) M. Di Mascio et al.   BLOOD

Scaling aspects of lymphocyte trafficking

(2008) Alan S. Perelson et al.   JOURNAL OF THEORETICAL BIOLOGY