Pt(II)-NHC Complex Induces ROS-ERS-Related DAMP Balance to Harness Immunogenic Cell Death in Hepatocellular Carcinoma
出版年份 2022 全文链接
标题
Pt(II)-NHC Complex Induces ROS-ERS-Related DAMP Balance to Harness Immunogenic Cell Death in Hepatocellular Carcinoma
作者
关键词
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出版物
JOURNAL OF MEDICINAL CHEMISTRY
Volume 65, Issue 3, Pages 1848-1866
出版商
American Chemical Society (ACS)
发表日期
2022-01-14
DOI
10.1021/acs.jmedchem.1c01248
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Immune Checkpoint Inhibitors in Novel Combinations for Hepatocellular Carcinoma
- (2021) Sharanya Maanasi Kalasekar et al. HEPATOLOGY
- A novel immune classification reveals distinct immune escape mechanism and genomic alterations: implications for immunotherapy in hepatocellular carcinoma
- (2021) Zaoqu Liu et al. Journal of Translational Medicine
- Hepatocellular carcinoma
- (2021) Josep M. Llovet et al. Nature Reviews Disease Primers
- Calreticulin—Multifunctional Chaperone in Immunogenic Cell Death: Potential Significance as a Prognostic Biomarker in Ovarian Cancer Patients
- (2021) Michal Kielbik et al. Cells
- An overview of anticancer platinum N-heterocyclic carbene complexes
- (2021) Sai Zhao et al. COORDINATION CHEMISTRY REVIEWS
- Cancer statistics, 2020
- (2020) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Endoplasmic Reticulum Targeting to Amplify Immunogenic Cell Death for Cancer Immunotherapy
- (2020) Hongzhang Deng et al. NANO LETTERS
- A novel platinum-based chemotherapeutic inducing immunogenic cell death
- (2020) Oliver Kepp et al. OncoImmunology
- A Platinum(IV) Prodrug – Perfluoroaryl Macrocyclic Peptide Conjugate Enhances Platinum Uptake in the Brain
- (2020) Colin M. Fadzen et al. JOURNAL OF MEDICINAL CHEMISTRY
- A Photocaged, Water-Oxidizing, and Nucleolus-Targeted Pt(IV) Complex with a Distinct Anticancer Mechanism
- (2020) Zhiqin Deng et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Current Approaches for Combination Therapy of Cancer: The Role of Immunogenic Cell Death
- (2020) Zahra Asadzadeh et al. Cancers
- Insights into P-Glycoprotein Inhibitors: New Inducers of Immunogenic Cell Death
- (2020) Joanna Kopecka et al. Cells
- PlatinER: a Highly Potent Anticancer Platinum(II) Complex that induces Endoplasmic Reticulum Stress‐driven Immunogenic Cell Death
- (2020) Max Jing Rui Tham et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- A Multitarget Gold(I) Complex Induces Cytotoxicity Related to Aneuploidy in HCT‐116 Colorectal Carcinoma Cells
- (2020) Jing‐Jing Zhang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Halo and Pseudohalo Gold(I)-NHC Complexes Derived from 4,5-Diarylimidazoles with Excellent in Vitro and in Vivo Anticancer Activity Against HCC
- (2020) Mianli Bian et al. JOURNAL OF MEDICINAL CHEMISTRY
- Oncolytic HSV therapy modulates vesicular trafficking inducing cisplatin sensitivity and anti-tumor immunity
- (2020) Balveen Kaur et al. CLINICAL CANCER RESEARCH
- Oxaliplatin induces immunogenic cell death in hepatocellular carcinoma cells and synergizes with immune checkpoint blockade therapy
- (2020) Hanzhang Zhu et al. CELLULAR ONCOLOGY
- An ER‐Targeting Iridium(III) Complex That Induces Immunogenic Cell Death in Non‐Small‐Cell Lung Cancer
- (2020) Lili Wang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- New copper complexes inducing bimodal death through apoptosis and autophagy in A549 cancer cells
- (2020) Noor Shad Gul et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Rationally Designed Redox-Active Au(I) N-Heterocyclic Carbene: An Immunogenic Cell Death Inducer
- (2020) Sajal Sen et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- DNA Intercalation Facilitates Efficient DNA-Targeted Covalent Binding of Phenanthriplatin
- (2019) Ali A. Almaqwashi et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Proteomics identifies new therapeutic targets of early-stage hepatocellular carcinoma
- (2019) Ying Jiang et al. NATURE
- Pt(IV) Bifunctional Prodrug Containing 2-(2-Propynyl)octanoato Axial Ligand: Induction of Immunogenic Cell Death on Colon Cancer
- (2019) Maurizio Sabbatini et al. JOURNAL OF MEDICINAL CHEMISTRY
- Fuplatin: An Efficient and Low-Toxic Dual-Prodrug
- (2019) Ran Zhang et al. JOURNAL OF MEDICINAL CHEMISTRY
- N-Heterocyclic Carbene Platinum Complexes: A Big Step Forward for Effective Antitumor Compounds
- (2019) Stéphane Bellemin-Laponnaz EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
- A new rhodium(I) NHC complex inhibits TrxR: In vitro cytotoxicity and in vivo hepatocellular carcinoma suppression
- (2019) Rong Fan et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis, DNA binding studies, and antiproliferative activity of novel Pt(II)-complexes with an L-alanyl-based ligand
- (2019) Claudia Riccardi et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Immunogenic cell death induced by a new photodynamic therapy based on photosens and photodithazine
- (2019) Victoria D. Turubanova et al. Journal for ImmunoTherapy of Cancer
- The effect of geometric isomerism on the anticancer activity of the monofunctional platinum complex trans-[Pt(NH3)2(phenanthridine)Cl]NO3
- (2018) Wen Zhou et al. CHEMICAL COMMUNICATIONS
- Anticancer metal-N-heterocyclic carbene complexes of gold, platinum and palladium
- (2018) Taotao Zou et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Mitochondria-targeted platinum(II) complexes induce apoptosis-dependent autophagic cell death mediated by ER-stress in A549 cancer cells
- (2018) Feng-Yang Wang et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Glutathione-Scavenging Poly(disulfide amide) Nanoparticles for the Effective Delivery of Pt(IV) Prodrugs and Reversal of Cisplatin Resistance
- (2018) Xiang Ling et al. NANO LETTERS
- New Platinum(II) Agent Induces Bimodal Death of Apoptosis and Autophagy Against A549 Cancer Cell
- (2018) Feng-Yang Wang et al. FREE RADICAL BIOLOGY AND MEDICINE
- Integrating the Epigenome to Identify Novel Drivers of Hepatocellular Carcinoma
- (2018) R A Hlady et al. HEPATOLOGY
- Stimuli-Responsive Therapeutic Metallodrugs
- (2018) Xiaohui Wang et al. CHEMICAL REVIEWS
- PD-L1 microSPECT/CT Imaging for Longitudinal Monitoring of PD-L1 Expression in Syngeneic and Humanized Mouse Models for Cancer
- (2018) Sandra Heskamp et al. Cancer Immunology Research
- Stimulus-responsive viral vectors for controlled delivery of therapeutics
- (2017) Mitchell J. Brun et al. JOURNAL OF CONTROLLED RELEASE
- Successful chemoimmunotherapy against hepatocellular cancer in a novel murine model
- (2017) Guangfu Li et al. JOURNAL OF HEPATOLOGY
- A Drug of Such Damned Nature.1 Challenges and Opportunities in Translational Platinum Drug Research
- (2017) Dorian M. Cheff et al. JOURNAL OF MEDICINAL CHEMISTRY
- A subset of platinum-containing chemotherapeutic agents kills cells by inducing ribosome biogenesis stress
- (2017) Peter M Bruno et al. NATURE MEDICINE
- Update on metal N-heterocyclic carbene complexes as potential anti-tumor metallodrugs
- (2016) Wukun Liu et al. COORDINATION CHEMISTRY REVIEWS
- Anticancer metal drugs and immunogenic cell death
- (2016) Alessio Terenzi et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Induction of Immunogenic Cell Death by Chemotherapeutic Platinum Complexes
- (2015) Daniel Yuan Qiang Wong et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Synthesis, structural characterization and in vitro anti-cancer activity of functionalized N-heterocyclic carbene platinum and palladium complexes
- (2015) Georges Dahm et al. JOURNAL OF ORGANOMETALLIC CHEMISTRY
- Trial Watch
- (2014) Erika Vacchelli et al. OncoImmunology
- Gold(III) Complexes Containing N-Heterocyclic Carbene Ligands: Thiol “Switch-on” Fluorescent Probes and Anti-Cancer Agents
- (2013) Taotao Zou et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Facing the dawn of immunotherapy for hepatocellular carcinoma
- (2013) Martin F. Sprinzl et al. JOURNAL OF HEPATOLOGY
- Antitumor trans-N-Heterocyclic Carbene–Amine–Pt(II) Complexes: Synthesis of Dinuclear Species and Exploratory Investigations of DNA Binding and Cytotoxicity Mechanisms
- (2013) Mélanie Chtchigrovsky et al. JOURNAL OF MEDICINAL CHEMISTRY
- Mouse models for liver cancer
- (2013) Latifa Bakiri et al. Molecular Oncology
- Adaptive immunity suppresses formation and progression of diethylnitrosamine-induced liver cancer
- (2012) Carlo Schneider et al. GUT
- Synthesis, Characterization, and in Vitro Studies of Bis[1,3-diethyl-4,5-diarylimidazol-2-ylidene]gold(I/III) Complexes
- (2012) Wukun Liu et al. JOURNAL OF MEDICINAL CHEMISTRY
- Ipilimumab: An Anti-CTLA-4 Antibody for Metastatic Melanoma
- (2011) E. J. Lipson et al. CLINICAL CANCER RESEARCH
- Synthesis and biological studies of silver N-heterocyclic carbene complexes derived from 4,5-diarylimidazole
- (2011) Wukun Liu et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- NHC Gold Halide Complexes Derived from 4,5-Diarylimidazoles: Synthesis, Structural Analysis, and Pharmacological Investigations as Potential Antitumor Agents
- (2011) Wukun Liu et al. JOURNAL OF MEDICINAL CHEMISTRY
- Potential of immunotherapy for hepatocellular carcinoma
- (2010) Ekaterina Breous et al. JOURNAL OF HEPATOLOGY
- Immunogenic death of colon cancer cells treated with oxaliplatin
- (2009) A Tesniere et al. ONCOGENE
- Diverse roles of invariant natural killer T cells in liver injury and fibrosis induced by carbon tetrachloride
- (2008) Ogyi Park et al. HEPATOLOGY
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