Periostin, an Emerging Player in Itch Sensation

A basophil-neuronal axis promotes itch

(2021) Fang Wang et al.   CELL

Itch intensity in prurigo nodularis is closely related with dermal interleukin‐31, oncostatin M, IL‐31 receptor alpha, and oncostatin M receptor beta

(2021) Takashi Hashimoto et al.   EXPERIMENTAL DERMATOLOGY

Neuronal branching of sensory neurons is associated with BDNF‐positive eosinophils in atopic dermatitis

(2020) Daria Guseva et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Dupilumab treatment results in early and sustained improvements in itch in adolescents and adults with moderate-to-severe atopic dermatitis: analysis of the randomized phase 3 studies SOLO 1 & SOLO 2, AD ADOL, and CHRONOS

(2020) Jonathan I. Silverberg et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Periostin Activation of Integrin Receptors on Sensory Neurons Induces Allergic Itch

(2020) Santosh K. Mishra et al.   Cell Reports

Itch in Organs Beyond the Skin

(2020) Rachel Shireen Golpanian et al.   CURRENT ALLERGY AND ASTHMA REPORTS

RNA Sequencing Keloid Transcriptome Associates Keloids With Th2, Th1, Th17/Th22, and JAK3-Skewing

(2020) Jianni Wu et al.   Frontiers in Immunology

Pruritus in ordinary scabies: IL ‐31 from macrophages induced by overexpression of TSLP and periostin

(2019) Takashi Hashimoto et al.   ALLERGY

Periostin: An emerging biomarker for allergic diseases

(2019) Kenji Izuhara et al.   ALLERGY

Itching as a systemic disease

(2019) Takashi Hashimoto et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Periostin is induced by IL-4/IL-13 in dermal fibroblasts and promotes RhoA/ROCK pathway-mediated TGF-β1 secretion in abnormal scar formation

(2019) Daisuke Maeda et al.   Journal of Plastic Surgery and Hand Surgery

Pathophysiological mechanisms of itch in bullous pemphigoid

(2019) Takashi Hashimoto et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Dupilumab is very effective in a large cohort of difficult‐to‐treat adult atopic dermatitis patients: First clinical and biomarker results from the BioDay registry

(2019) Lieneke F. M. Ariëns et al.   ALLERGY

Mechanisms of Itch in Stasis Dermatitis: Significant Role of IL-31 from Macrophages

(2019) Takashi Hashimoto et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Atopic Dermatitis Linked Cytokine Interleukin-31 Induced Itch Mediated via a Neuropeptide Natriuretic Polypeptide B

(2018) S Pitake et al.   ACTA DERMATO-VENEREOLOGICA

Characteristics of Chronic Itch in Systemic Sclerosis: A Cross-sectional Survey

(2018) C Stull et al.   ACTA DERMATO-VENEREOLOGICA

Prurigo Nodularis and Its Management

(2018) Claudia Zeidler et al.   DERMATOLOGIC CLINICS

Possible Roles of Basophils in Chronic Itch

(2018) Takashi Hashimoto et al.   EXPERIMENTAL DERMATOLOGY

Pro-fibrotic phenotype of human skin fibroblasts induced by periostin via modulating TGF-β signaling

(2018) Miwa Kanaoka et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Inflammatory cytokines and peripheral mediators in the pathophysiology of pruritus in cutaneous T-cell lymphoma

(2018) D.J. Lewis et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Anatomical and functional dichotomy of ocular itch and pain

(2018) Cheng-Chiu Huang et al.   NATURE MEDICINE

Dupilumab progressively improves systemic and cutaneous abnormalities in atopic dermatitis patients

(2018) Emma Guttman-Yassky et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Itch: From mechanism to (novel) therapeutic approaches

(2018) Gil Yosipovitch et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Non-Histaminergic Itch Mediators Elevated in the Skin of a Porcine Model of Scabies and of Human Scabies Patients

(2018) Kristen M. Sanders et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Periostin deletion suppresses late-phase response in mouse experimental allergic conjunctivitis

(2018) Yosuke Asada et al.   ALLERGOLOGY INTERNATIONAL

Therapeutic pipeline for atopic dermatitis: End of the drought?

(2017) Amy S. Paller et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Scratching the itch: is scabies a truly neglected disease?

(2017) Olivier Chosidow et al.   LANCET INFECTIOUS DISEASES

Thymic Stromal Chemokine TSLP Acts through Th2 Cytokine Production to Induce Cutaneous T-cell Lymphoma

(2016) Naomi Takahashi et al.   CANCER RESEARCH

Periostin upregulates the effector functions of eosinophils

(2016) Toru Noguchi et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A histamine-independent itch pathway is required for allergic ocular itch

(2016) Cheng-Chiu Huang et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The usefulness of measuring tear periostin for the diagnosis and management of ocular allergic diseases

(2016) Hiroshi Fujishima et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Strategy for treatment of fibrosis in systemic sclerosis: Present and future

(2016) Koichi Yanaba   JOURNAL OF DERMATOLOGY

Early Activation of Th2/Th22 Inflammatory and Pruritogenic Pathways in Acute Canine Atopic Dermatitis Skin Lesions

(2016) Thierry Olivry et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Keloids: The paradigm of skin fibrosis — Pathomechanisms and treatment

(2016) Jonathan P. Andrews et al.   MATRIX BIOLOGY

Itch Prevalence and Characteristics in a Hispanic Geriatric Population: A Comprehensive Study Using a Standardized Itch Questionnaire

(2015) R Valdes-Rodriguez et al.   ACTA DERMATO-VENEREOLOGICA

Management of bullous pemphigoid: the European Dermatology Forum consensus in collaboration with the European Academy of Dermatology and Venereology

(2015) C. Feliciani et al.   BRITISH JOURNAL OF DERMATOLOGY

The possible interaction between periostin expressed by cancer stroma and tumor-associated macrophages in developing mycosis fungoides

(2015) Sadanori Furudate et al.   EXPERIMENTAL DERMATOLOGY

Eosinophil-dependent skin innervation and itching following contact toxicant exposure in mice

(2015) James J. Lee et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Expression of Periostin in Normal, Atopic, and Nonatopic Chronically Inflamed Canine Skin

(2015) T. Mineshige et al.   VETERINARY PATHOLOGY

Periostin levels correlate with disease severity and chronicity in patients with atopic dermatitis

(2014) K. Kou et al.   BRITISH JOURNAL OF DERMATOLOGY

Expressions and Roles of Periostin in Otolaryngological Diseases

(2014) Nobuo Ohta et al.   ALLERGOLOGY INTERNATIONAL

Molecular Mechanisms That Influence the Macrophage M1–M2 Polarization Balance

(2014) Nan Wang et al.   Frontiers in Immunology

The Epithelial Cell-Derived Atopic Dermatitis Cytokine TSLP Activates Neurons to Induce Itch

(2013) Sarah R. Wilson et al.   CELL

The Cells and Circuitry for Itch Responses in Mice

(2013) S. K. Mishra et al.   SCIENCE

Serum periostin levels are correlated with progressive skin sclerosis in patients with systemic sclerosis

(2012) Y. Yamaguchi et al.   BRITISH JOURNAL OF DERMATOLOGY

Periostin promotes chronic allergic inflammation in response to Th2 cytokines

(2012) Miho Masuoka et al.   JOURNAL OF CLINICAL INVESTIGATION

Periostin Facilitates Skin Sclerosis via PI3K/Akt Dependent Mechanism in a Mouse Model of Scleroderma

(2012) Lingli Yang et al.   PLoS One

Periostin Contributes to the Pathogenesis of Atopic Dermatitis by Inducing TSLP Production from Keratinocytes

(2012) Hiroshi Shiraishi et al.   ALLERGOLOGY INTERNATIONAL

Expression of Pendrin Periostin in Allergic Rhinitis Chronic Rhinosinusitis

(2012) Akihiro Ishida et al.   ALLERGOLOGY INTERNATIONAL

Basophil recruitment and activation in inflammatory skin diseases

(2011) Y. Ito et al.   ALLERGY

Pathogenesis of Bullous Pemphigoid

(2011) Hideyuki Ujiie et al.   DERMATOLOGIC CLINICS

TRPV1-lineage neurons are required for thermal sensation

(2010) Santosh K Mishra et al.   EMBO JOURNAL

TRPV1-mediated itch in seasonal allergic rhinitis

(2009) L. Alenmyr et al.   ALLERGY

Periostin localizes to cells in normal skin, but is associated with the extracellular matrix during wound repair

(2009) Linda Jackson-Boeters et al.   Journal of Cell Communication and Signaling