Mitochondria-targeted Pt(IV) prodrugs conjugated with an aggregation-induced emission luminogen against breast cancer cells by dual modulation of apoptosis and autophagy inhibition

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2021) Hyuna Sung et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Sugar-Based Aggregation-Induced Emission Luminogens: Design, Structures, and Applications

(2020) Yijia Wang et al.   CHEMICAL REVIEWS

Aggregation‐induced Emission Based Fluorogens for Mitochondria‐targeted Tumor Imaging and Theranostics

(2020) Kaiwu Yu et al.   Chemistry-An Asian Journal

Amphiphilic Tetraphenylethene-Based Pyridinium Salt for Selective Cell-Membrane Imaging and Room-Light-Induced Special Reactive Oxygen Species Generation

(2019) Weijie Zhang et al.   ACS Applied Materials & Interfaces

A cisplatin-based platinum(IV) prodrug containing a glutathione s-transferase inhibitor to reverse cisplatin-resistance in non-small cell lung cancer

(2019) Hong Chen et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Fluorogenic reaction-based prodrug conjugates as targeted cancer theranostics

(2018) Min Hee Lee et al.   CHEMICAL SOCIETY REVIEWS

Mechanism and medical implications of mammalian autophagy

(2018) Ivan Dikic et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Impact of Mitochondrion-Targeting Group on the Reactivity and Cytostatic Pathway of Platinum(IV) Complexes

(2018) Suxing Jin et al.   INORGANIC CHEMISTRY

Stimuli-Responsive Therapeutic Metallodrugs

(2018) Xiaohui Wang et al.   CHEMICAL REVIEWS

Mitochondria and Cancer

(2016) Sejal Vyas et al.   CELL

The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs

(2016) Timothy C. Johnstone et al.   CHEMICAL REVIEWS

Iridium(III) Anthraquinone Complexes as Two-Photon Phosphorescence Probes for Mitochondria Imaging and Tracking under Hypoxia

(2016) Lingli Sun et al.   CHEMISTRY-A EUROPEAN JOURNAL

A platinum prodrug conjugated with a photosensitizer with aggregation-induced emission (AIE) characteristics for drug activation monitoring and combinatorial photodynamic–chemotherapy against cisplatin resistant cancer cells

(2015) Youyong Yuan et al.   CHEMICAL COMMUNICATIONS

Apoptotic Caspases Suppress mtDNA-Induced STING-Mediated Type I IFN Production

(2014) Michael J. White et al.   CELL

A targeted theranostic platinum(iv) prodrug containing a luminogen with aggregation-induced emission (AIE) characteristics for in situ monitoring of drug activation

(2014) Youyong Yuan et al.   CHEMICAL COMMUNICATIONS

Pt(IV) Prodrugs Designed to Bind Non-Covalently to Human Serum Albumin for Drug Delivery

(2014) Yao-Rong Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Targeted Theranostic Platinum(IV) Prodrug with a Built-In Aggregation-Induced Emission Light-Up Apoptosis Sensor for Noninvasive Early Evaluation of Its Therapeutic Responses in Situ

(2014) Youyong Yuan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Reactive Oxygen Species (ROS)-Responsive Polymer for Safe, Efficient, and Targeted Gene Delivery in Cancer Cells

(2013) Min Suk Shim et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Novel monofunctional platinum (II) complex Mono-Pt induces apoptosis-independent autophagic cell death in human ovarian carcinoma cells, distinct from cisplatin

(2013) Wen-Jie Guo et al.   Autophagy

A bioenergetic profile of non-transformed fibroblasts uncovers a link between death-resistance and enhanced spare respiratory capacity

(2013) Kristen P. Nickens et al.   MITOCHONDRION

Targeting and delivery of platinum-based anticancer drugs

(2012) Xiaoyong Wang et al.   CHEMICAL SOCIETY REVIEWS

Next-Generation Anticancer Metallodrugs

(2012) Seiji Komeda et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Molecular and Cellular Characterization of the Biological Effects of Ruthenium(II) Complexes Incorporating 2-Pyridyl-2-pyrimidine-4-carboxylic Acid

(2012) Vanessa Pierroz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Autophagy modulation for cancer therapy

(2011) Zhineng J. Yang et al.   CANCER BIOLOGY & THERAPY

Pt(IV) complexes as prodrugs for cisplatin

(2011) Yi Shi et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Functional relevance of the histone  H2Ax in the response to DNA damaging agents

(2011) I. Revet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

The status of platinum anticancer drugs in the clinic and in clinical trials

(2010) Nial J. Wheate et al.   DALTON TRANSACTIONS

p62 at the Crossroads of Autophagy, Apoptosis, and Cancer

(2009) Jorge Moscat et al.   CELL

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE