The root extract of Scutellaria baicalensis Georgi promotes β cell function and protects from apoptosis by inducing autophagy

Autophagy in inflammation, infection, and immunometabolism

(2021) Vojo Deretic   IMMUNITY

A Destiny for Degradation: Interplay between Cullin-RING E3 Ligases and Autophagy

(2021) Guang Lu et al.   TRENDS IN CELL BIOLOGY

Therapeutic opportunities for pancreatic β-cell ER stress in diabetes mellitus

(2021) Jing Yong et al.   Nature Reviews Endocrinology

The role of regulated necrosis in endocrine diseases

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Mitochondria and T2D: Role of Autophagy, ER Stress, and Inflammasome

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Cell death: a review of the major forms of apoptosis, necrosis and autophagy

(2019) Mark S D’Arcy   CELL BIOLOGY INTERNATIONAL

The Reference Genome Sequence of Scutellaria baicalensis Provides Insights into the Evolution of Wogonin Biosynthesis

(2019) Qing Zhao et al.   Molecular Plant

Baicalein improves glucose metabolism in insulin resistant HepG2 cells

(2019) Zongchun Yang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Scutellaria baicalensis Georgi. (Lamiaceae): a review of its traditional uses, botany, phytochemistry, pharmacology and toxicology

(2019) Tiantian Zhao et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

The Beta Cell in Type 2 Diabetes

(2019) Ashley A. Christensen et al.   Current Diabetes Reports

WITHDRAWN: Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: results from the International Diabetes Federation Diabetes Atlas, 9th edition

(2019) Pouya Saeedi et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Mechanisms of Autophagy in Metabolic Stress Response

(2019) Angelina S. Gross et al.   JOURNAL OF MOLECULAR BIOLOGY

CASP9 (caspase 9) is essential for autophagosome maturation through regulation of mitochondrial homeostasis

(2019) Hyun-Kyu An et al.   Autophagy

Xiaokeping-induced autophagy protects pancreatic β-cells against apoptosis under high glucose stress

(2018) Yanyang Wu et al.   BIOMEDICINE & PHARMACOTHERAPY

Interleukin-6 Reduces β-Cell Oxidative Stress by Linking Autophagy With the Antioxidant Response

(2018) Michelle R. Marasco et al.   DIABETES

The BECN1-BCL2 complex regulates insulin secretion and storage in mice

(2018) Kenta Kuramoto et al.   Autophagy

Advances in immunotherapy of type I diabetes

(2018) Qianqian Ni et al.   ADVANCED DRUG DELIVERY REVIEWS

Scutellariae Radix and Coptidis Rhizoma Improve Glucose and Lipid Metabolism in T2DM Rats via Regulation of the Metabolic Profiling and MAPK/PI3K/Akt Signaling Pathway

(2018) Xiang Cui et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Gymnemic acid I triggers mechanistic target of rapamycin-mediated β cells cytoprotection through the promotion of autophagy under high glucose stress

(2018) Yanyang Wu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Baicalein protects rat insulinoma INS-1 cells from palmitate-induced lipotoxicity by inducing HO-1

(2017) Hyun Jeong Kwak et al.   PLoS One

Autophagy is a major regulator of beta cell insulin homeostasis

(2016) Yael Riahi et al.   DIABETOLOGIA

Sex and Gender Differences in Risk, Pathophysiology and Complications of Type 2 Diabetes Mellitus

(2016) Alexandra Kautzky-Willer et al.   ENDOCRINE REVIEWS

Insulin secretory granules control autophagy in pancreatic   cells

(2015) A. Goginashvili et al.   SCIENCE

Autophagy deficiency in β cells blunts incretin-induced suppression of glucagon release from α cells

(2015) Min Joo Kim et al.   Islets

Autophagy and apoptosis: where do they meet?

(2014) Subhadip Mukhopadhyay et al.   APOPTOSIS

Simulated gastrointestinal tract metabolism and pharmacological activities of water extract of Scutellaria baicalensis roots

(2014) Shihua Xing et al.   JOURNAL OF ETHNOPHARMACOLOGY

Baicalein Protects against Type 2 Diabetes via Promoting Isletβ-Cell Function in Obese Diabetic Mice

(2014) Yu Fu et al.   International Journal of Endocrinology

Autophagy plays a protective role in endoplasmic reticulum stress-mediated pancreatic β cell death

(2012) Alberto Bartolome et al.   Autophagy

Diabetes Mellitus and the β Cell: The Last Ten Years

(2012) Frances M. Ashcroft et al.   CELL

When less is more: the forbidden fruits of gene repression in the adult β-cell

(2012) T. J. Pullen et al.   DIABETES OBESITY & METABOLISM