Dual Mechanism of Integrin αIIbβ3Closure in Procoagulant Platelets

Both TMEM16F-dependent and TMEM16F-independent pathways contribute to phosphatidylserine exposure in platelet apoptosis and platelet activation

(2013) R. van Kruchten et al.   BLOOD

JAM-A protects from thrombosis by suppressing integrin  IIb 3-dependent outside-in signaling in platelets

(2012) M. U. Naik et al.   BLOOD

Talin activates integrins by altering the topology of the β transmembrane domain

(2012) Chungho Kim et al.   JOURNAL OF CELL BIOLOGY

Targeted gene inactivation reveals a functional role of calpain-1 in platelet spreading

(2012) S. M. KUCHAY et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Platelet-based coagulation: different populations, different functions

(2012) J. W. M. HEEMSKERK et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Compound heterozygosity for 2 novel TMEM16F mutations in a patient with Scott syndrome

(2011) E. Castoldi et al.   BLOOD

Arterial thrombosis—insidious, unpredictable and deadly

(2011) Shaun P Jackson   NATURE MEDICINE

Key role of glycoprotein Ib/V/IX and von Willebrand factor in platelet activation-dependent fibrin formation at low shear flow

(2010) J. M. E. M. Cosemans et al.   BLOOD

Functional Divergence of Platelet Protein Kinase C (PKC) Isoforms in Thrombus Formation on Collagen

(2010) Karen Gilio et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Roles of Platelet STIM1 and Orai1 in Glycoprotein VI- and Thrombin-dependent Procoagulant Activity and Thrombus Formation

(2010) Karen Gilio et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Potentiating role of Gas6 and Tyro3, Axl and Mer (TAM) receptors in human and murine platelet activation and thrombus stabilization

(2010) J. M. E. M. COSEMANS et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Calcium-dependent phospholipid scrambling by TMEM16F

(2010) Jun Suzuki et al.   NATURE

The final steps of integrin activation: the end game

(2010) Sanford J. Shattil et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Spatial Distribution of Factor Xa, Thrombin, and Fibrin(ogen) on Thrombi at Venous Shear

(2010) Michelle A. Berny et al.   PLoS One

Rapid Procoagulant Phosphatidylserine Exposure Relies on High Cytosolic Calcium Rather Than on Mitochondrial Depolarization

(2009) Amal Arachiche et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Integrins in platelet activation

(2009) B. NIESWANDT et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Mitochondrial control of platelet apoptosis: effect of cyclosporin A, an inhibitor of the mitochondrial permeability transition pore

(2009) Valery Leytin et al.   LABORATORY INVESTIGATION

Multiple ways to switch platelet integrins on and off

(2008) J. M. E. M. COSEMANS et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS