标题
Neurodegenerative Disorders: Spotlight on Sphingolipids
作者
关键词
-
出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 22, Issue 21, Pages 11998
出版商
MDPI AG
发表日期
2021-11-05
DOI
10.3390/ijms222111998
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Cross-talks among GBA mutations, glucocerebrosidase, and α-synuclein in GBA-associated Parkinson’s disease and their targeted therapeutic approaches: a comprehensive review
- (2021) Tapan Behl et al. Translational Neurodegeneration
- The Importance of Drosophila melanogaster Research to UnCover Cellular Pathways Underlying Parkinson’s Disease
- (2021) Melissa Vos et al. Cells
- Parkinson's disease
- (2021) Bastiaan R Bloem et al. LANCET
- The Role of Ceramide Metabolism and Signaling in the Regulation of Mitophagy and Cancer Therapy
- (2021) Megan Sheridan et al. Cancers
- SIRT1 regulates sphingolipid metabolism and neural differentiation of mouse embryonic stem cells through c-Myc-SMPDL3B
- (2021) Wei Fan et al. eLife
- The Multiple Roles of Sphingomyelin in Parkinson’s Disease
- (2021) Paola Signorelli et al. Biomolecules
- Ceramide accumulation induces mitophagy and impairs β-oxidation in PINK1 deficiency
- (2021) Melissa Vos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Probiotic Bacillus subtilis Protects against α-Synuclein Aggregation in C. elegans
- (2020) María Eugenia Goya et al. Cell Reports
- Genetics of Parkinson's disease: An introspection of its journey towards precision medicine
- (2020) Sara Bandres-Ciga et al. NEUROBIOLOGY OF DISEASE
- Fatty acid 2-hydroxylase (FA2H) as a stimulatory molecule responsible for breast cancer cell migration
- (2020) Masayo Hirao-Suzuki et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Overexpression of Fatty Acid 2-Hydroxylase is Associated with an Increased Sensitivity to Cisplatin by Ovarian Cancer and Better Prognoses
- (2020) Ting Qi et al. Genetic Testing and Molecular Biomarkers
- miR-300/FA2H affects gastric cancer cell proliferation and apoptosis
- (2020) Bo Hong et al. Open Medicine
- GBA-Associated Synucleinopathies: Prime Candidates for Alpha-Synuclein Targeting Compounds
- (2020) Kathrin Brockmann Frontiers in Cell and Developmental Biology
- Mitochondrial Dysfunction, Oxidative Stress and Neuroinflammation in Neurodegeneration with Brain Iron Accumulation (NBIA)
- (2020) Isabel Hinarejos et al. Antioxidants
- 2-Hydroxylation of Fatty Acids Represses Colorectal Tumorigenesis and Metastasis via the YAP Transcriptional Axis
- (2020) Liang Sun et al. CANCER RESEARCH
- Decreased turnover of the CNS myelin protein Opalin in a mouse model of hereditary spastic paraplegia 35
- (2020) Robert Hardt et al. HUMAN MOLECULAR GENETICS
- The effect of mutant GBA1 on accumulation and aggregation of α-synuclein
- (2019) Gali Maor et al. HUMAN MOLECULAR GENETICS
- FAHN/SPG35: a narrow phenotypic spectrum across disease classifications
- (2019) Tim W Rattay et al. BRAIN
- Lewy pathology in Parkinson’s disease consists of crowded organelles and lipid membranes
- (2019) Sarah H. Shahmoradian et al. NATURE NEUROSCIENCE
- FA2H Exhibits Tumor Suppressive Roles on Breast Cancers via Cancer Stemness Control
- (2019) Xiaofeng Dai et al. Frontiers in Oncology
- Phospholipase PLA2G6, a Parkinsonism-Associated Gene, Affects Vps26 and Vps35, Retromer Function, and Ceramide Levels, Similar to α-Synuclein Gain
- (2018) Guang Lin et al. Cell Metabolism
- Pla2g6 Deficiency in Zebrafish Leads to Dopaminergic Cell Death, Axonal Degeneration, Increased β-Synuclein Expression, and Defects in Brain Functions and Pathways
- (2018) Elena Sánchez et al. MOLECULAR NEUROBIOLOGY
- Genotype-Phenotype Relations for the Parkinson's Disease Genes Parkin , PINK1 , DJ1: MDSGene Systematic Review
- (2018) Meike Kasten et al. MOVEMENT DISORDERS
- ER Lipid Defects in Neuropeptidergic Neurons Impair Sleep Patterns in Parkinson’s Disease
- (2018) Jorge S. Valadas et al. NEURON
- C. Elegans Fatty Acid Two-Hydroxylase Regulates Intestinal Homeostasis by Affecting Heptadecenoic Acid Production
- (2018) Yuanbao Li et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- PLA2G6-Associated Neurodegeneration (PLAN): Review of Clinical Phenotypes and Genotypes
- (2018) Yu-pei Guo et al. Frontiers in Neurology
- Cardiolipin promotes electron transport between ubiquinone and complex I to rescuePINK1deficiency
- (2017) Melissa Vos et al. JOURNAL OF CELL BIOLOGY
- Changes in Red Blood Cell membrane lipid composition: A new perspective into the pathogenesis of PKAN
- (2017) Manar Aoun et al. MOLECULAR GENETICS AND METABOLISM
- White Matter Plasticity in the Adult Brain
- (2017) Cassandra Sampaio-Baptista et al. NEURON
- iPSC-derived neuronal models of PANK2-associated neurodegeneration reveal mitochondrial dysfunction contributing to early disease
- (2017) Charles Arber et al. PLoS One
- LRRK2 deficiency impacts ceramide metabolism in brain
- (2016) Ruggero Ferrazza et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The contribution of mutantGBAto the development of Parkinson disease inDrosophila
- (2016) Gali Maor et al. HUMAN MOLECULAR GENETICS
- A LRRK2-Dependent EndophilinA Phosphoswitch Is Critical for Macroautophagy at Presynaptic Terminals
- (2016) Sandra-Fausia Soukup et al. NEURON
- Impairment of PARK14-dependent Ca2+ signalling is a novel determinant of Parkinson’s disease
- (2016) Qingde Zhou et al. Nature Communications
- Loss ofPLA2G6leads to elevated mitochondrial lipid peroxidation and mitochondrial dysfunction
- (2015) Kerri J. Kinghorn et al. BRAIN
- Review: Insights into molecular mechanisms of disease in neurodegeneration with brain iron accumulation: unifying theories
- (2015) C. E. Arber et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Gaucher Disease: Clinical, Biological and Therapeutic Aspects
- (2015) Azza Dandana et al. PATHOBIOLOGY
- Therapeutic strategies in Parkinson's disease: what we have learned from animal models
- (2014) Jorge S. Valadas et al. Annals of the New York Academy of Sciences
- Pathogenesis of synaptic degeneration in Alzheimer's disease and Lewy body disease
- (2014) Cassia R. Overk et al. BIOCHEMICAL PHARMACOLOGY
- Genome-wide RNAi screen identifies the Parkinson disease GWAS risk locus SREBF1 as a regulator of mitophagy
- (2014) R. M. Ivatt et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PINK1 Loss-of-Function Mutations Affect Mitochondrial Complex I Activity via NdufA10 Ubiquinone Uncoupling
- (2014) V. A. Morais et al. SCIENCE
- The emerging role of nutrition in Parkinson's disease
- (2014) Stacey E. Seidl et al. Frontiers in Aging Neuroscience
- Ceramide and the mitochondrial respiratory chain
- (2013) Aviram Kogot-Levin et al. BIOCHIMIE
- Altered ceramide acyl chain length and ceramide synthase gene expression in Parkinson's disease
- (2013) Sarah K. Abbott et al. MOVEMENT DISORDERS
- Unfolded protein response in Gaucher disease: from human to Drosophila
- (2013) Gali Maor et al. Orphanet Journal of Rare Diseases
- Plasma Ceramide and Glucosylceramide Metabolism Is Altered in Sporadic Parkinson's Disease and Associated with Cognitive Impairment: A Pilot Study
- (2013) Michelle M. Mielke et al. PLoS One
- Near-Infrared 808 nm Light Boosts Complex IV-Dependent Respiration and Rescues a Parkinson-Related pink1 Model
- (2013) Melissa Vos et al. PLoS One
- Extensive aggregation of α-synuclein and tau in juvenile-onset neuroaxonal dystrophy: an autopsied individual with a novel mutation in the PLA2G6 gene-splicing site
- (2013) Yuichi Riku et al. Acta Neuropathologica Communications
- Misfolded SOD1 and ALS: Zeroing in on mitochondria
- (2012) Sarah Pickles et al. Amyotrophic Lateral Sclerosis
- Pantothenate kinase-associated neurodegeneration: altered mitochondria membrane potential and defective respiration in Pank2 knock-out mouse model
- (2012) Dario Brunetti et al. HUMAN MOLECULAR GENETICS
- Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy
- (2012) R David Sentelle et al. Nature Chemical Biology
- LRRK2 Controls an EndoA Phosphorylation Cycle in Synaptic Endocytosis
- (2012) Samer Matta et al. NEURON
- Vitamin K2 Is a Mitochondrial Electron Carrier That Rescues Pink1 Deficiency
- (2012) M. Vos et al. SCIENCE
- Induction of apoptotic erythrocyte death by rotenone
- (2012) Adrian Lupescu et al. TOXICOLOGY
- Central nervous system dysfunction in a mouse model of Fa2h deficiency
- (2011) Kathleen A. Potter et al. GLIA
- Roles of the Drosophila LRRK2 homolog in Rab7-dependent lysosomal positioning
- (2011) M. W. Dodson et al. HUMAN MOLECULAR GENETICS
- Neuroaxonal Dystrophy in Calcium-Independent Phospholipase A2 Deficiency Results from Insufficient Remodeling and Degeneration of Mitochondrial and Presynaptic Membranes
- (2011) G. Beck et al. JOURNAL OF NEUROSCIENCE
- Metabolic consequences of mitochondrial coenzyme A deficiency in patients with PANK2 mutations
- (2011) Valerio Leoni et al. MOLECULAR GENETICS AND METABOLISM
- Syndromes of neurodegeneration with brain iron accumulation (NBIA): An update on clinical presentations, histological and genetic underpinnings, and treatment considerations
- (2011) Susanne A. Schneider et al. MOVEMENT DISORDERS
- Iron-related MRI images in patients with pantothenate kinase-associated neurodegeneration (PKAN) treated with deferiprone: Results of a phase II pilot trial
- (2011) Giovanna Zorzi et al. MOVEMENT DISORDERS
- Chain length-specific properties of ceramides
- (2011) Sabine Grösch et al. PROGRESS IN LIPID RESEARCH
- Effect of endogenous mutant and wild-type PINK1 on Parkin in fibroblasts from Parkinson disease patients
- (2010) A. Rakovic et al. HUMAN MOLECULAR GENETICS
- Mitochondrial matters of the brain: the role in Huntington’s disease
- (2010) C. Turner et al. JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
- Widespread Lewy body and tau accumulation in childhood and adult onset dystonia-parkinsonism cases with PLA2G6 mutations
- (2010) Coro Paisán-Ruiz et al. NEUROBIOLOGY OF AGING
- Pantethine rescues a Drosophila model for pantothenate kinase-associated neurodegeneration
- (2010) A. Rana et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
- (2010) Derek P. Narendra et al. PLOS BIOLOGY
- Parkin-induced mitophagy in the pathogenesis of Parkinson disease
- (2009) Derek Narendra et al. Autophagy
- Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function
- (2009) Vanessa A. Morais et al. EMBO Molecular Medicine
- Mitochondrial accumulation of APP and Aβ: significance for Alzheimer disease pathogenesis
- (2009) Pavel F. Pavlov et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Disrupted Membrane Homeostasis and Accumulation of Ubiquitinated Proteins in a Mouse Model of Infantile Neuroaxonal Dystrophy Caused by PLA2G6 Mutations
- (2008) Ibrahim Malik et al. AMERICAN JOURNAL OF PATHOLOGY
- The sphingolipid salvage pathway in ceramide metabolism and signaling
- (2008) Kazuyuki Kitatani et al. CELLULAR SIGNALLING
- Mitochondrial Import and Accumulation of α-Synuclein Impair Complex I in Human Dopaminergic Neuronal Cultures and Parkinson Disease Brain
- (2008) Latha Devi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Bioactive sphingolipids: metabolism and function
- (2008) Nana Bartke et al. JOURNAL OF LIPID RESEARCH
- Thematic Review Series: Sphingolipids.Biodiversity of sphingoid bases (“sphingosines”) and related amino alcohols
- (2008) Sarah T. Pruett et al. JOURNAL OF LIPID RESEARCH
- Neuroaxonal Dystrophy Caused by Group VIA Phospholipase A2 Deficiency in Mice: A Model of Human Neurodegenerative Disease
- (2008) K. Shinzawa et al. JOURNAL OF NEUROSCIENCE
- Absence of 2-Hydroxylated Sphingolipids Is Compatible with Normal Neural Development But Causes Late-Onset Axon and Myelin Sheath Degeneration
- (2008) I. Zoller et al. JOURNAL OF NEUROSCIENCE
- Principles of bioactive lipid signalling: lessons from sphingolipids
- (2008) Yusuf A. Hannun et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More