Daphnetin inhibits corneal inflammation and neovascularization on a mouse model of corneal alkali burn

Daphnetin inhibits spinal glial activation via Nrf2/HO-1/NF-κB signaling pathway and attenuates CFA-induced inflammatory pain

(2021) Yifan Yang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Cucurbitacin B inhibits non-small cell lung cancer in vivo and in vitro by triggering TLR4/NLRP3/GSDMD-dependent pyroptosis

(2021) Renyikun Yuan et al.   PHARMACOLOGICAL RESEARCH

Pharmacological Inhibition of Caspase-8 Suppresses Inflammation-Induced Angiogenesis in the Cornea

(2020) Yunzhe Tian et al.   Biomolecules

Keratocytes promote corneal neovascularization through VEGFr3 induced by PPARα-inhibition

(2020) Xue Wang et al.   EXPERIMENTAL EYE RESEARCH

The artemisinin analog SM934 alleviates dry eye disease in rodent models by regulating TLR4/NF-κB/NLRP3 signaling

(2020) Fang-ming Yang et al.   ACTA PHARMACOLOGICA SINICA

Daphnetin suppresses experimental abdominal aortic aneurysms in mice via inhibition of aortic mural inflammation

(2020) Shiyun Xie et al.   Experimental and Therapeutic Medicine

Corneal neovascularization

(2020) Matthew P. Nicholas et al.   EXPERIMENTAL EYE RESEARCH

Regulation of VEGFR2 trafficking and signaling by Rab GTPase-activating proteins

(2019) Ye Xie et al.   Scientific Reports

Daphnetin alleviates lipopolysaccharide/ d -galactosamine-induced acute liver failure via the inhibition of NLRP3, MAPK and NF-κB, and the induction of autophagy

(2018) Hongming Lv et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

β-Escin Effectively Modulates HUVECs Proliferation and Tube Formation

(2018) Lenka Varinská et al.   MOLECULES

Inhibition of NLRP3 Inflammasome Pathway by Butyrate Improves Corneal Wound Healing in Corneal Alkali Burn

(2017) Fang Bian et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Global causes of blindness and distance vision impairment 1990–2020: a systematic review and meta-analysis

(2017) Seth R Flaxman et al.   Lancet Global Health

Peroxisome proliferator-activated receptor alpha agonist suppresses neovascularization by reducing both vascular endothelial growth factor and angiopoietin-2 in corneal alkali burn

(2017) Takeshi Arima et al.   Scientific Reports

Daphnetin ameliorates 7,12-dimethylbenz[a]anthracene-induced mammary carcinogenesis through Nrf-2-Keap1 and NF-κB pathways

(2016) Abhishek Kumar et al.   BIOMEDICINE & PHARMACOTHERAPY

Daphnetin inhibits TNF-α and VEGF-induced angiogenesis through inhibition of the IKKs/IκBα/NF-κB, Src/FAK/ERK1/2 and Akt signalling pathways

(2016) Abhishek Kumar et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Daphnetin protects oxidative stress-induced neuronal apoptosis via regulation of MAPK signaling and HSP70 expression

(2016) Zhilin Qi et al.   Oncology Letters

Daphnetin Protects against Cerebral Ischemia/Reperfusion Injury in Mice via Inhibition of TLR4/NF-κB Signaling Pathway

(2016) Jia Liu et al.   Biomed Research International

Injectable gelatin derivative hydrogels with sustained vascular endothelial growth factor release for induced angiogenesis

(2015) Zhe Li et al.   Acta Biomaterialia

Anti-inflammatory and Protective Properties of Daphnetin in Endotoxin-Induced Lung Injury

(2014) Wen-wen Yu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Therapeutic effect of daphnetin on the autoimmune arthritis through demethylation of proapoptotic genes in synovial cells

(2014) Kuanyong Shu et al.   Journal of Translational Medicine

Control of angiogenesis by VEGF and endostatin-encapsulated protein microcrystals and inhibition of tumor angiogenesis

(2013) Goichi Matsumoto et al.   BIOMATERIALS

Anti-VEGF Treatment of Corneal Neovascularization

(2012) Anne M. Keating et al.   Ocular Surface

Corneal Neovascularization: An Anti-VEGF Therapy Review

(2012) Jin-Hong Chang et al.   SURVEY OF OPHTHALMOLOGY

Differential effects of esculetin and daphnetin on in vitro cell proliferation and in vivo estrogenicity

(2011) Fausto Alejandro Jiménez-Orozco et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

ZD6474, a dual tyrosine kinase inhibitor of EGFR and VEGFR-2, inhibits MAPK/ERK and AKT/PI3-K and induces apoptosis in breast cancer cells

(2010) Siddik Sarkar et al.   CANCER BIOLOGY & THERAPY

Corneal Neovascularization as a Risk Factor for Graft Failure and Rejection after Keratoplasty

(2010) Bjorn Bachmann et al.   OPHTHALMOLOGY

An overview of small-molecule inhibitors of VEGFR signaling

(2009) S. Percy Ivy et al.   Nature Reviews Clinical Oncology

Therapeutic effects of daphnetin on adjuvant-induced arthritic rats

(2008) Qin Gao et al.   JOURNAL OF ETHNOPHARMACOLOGY