Declines in PDE4B activity promote myopia progression through downregulation of scleral collagen expression

Cardiac Overexpression of PDE4B Blunts β-Adrenergic Response and Maladaptive Remodeling in Heart Failure

(2020) Sarah Karam et al.   CIRCULATION

Meta-analysis of 542,934 subjects of European ancestry identifies new genes and mechanisms predisposing to refractive error and myopia

(2020) Pirro G. Hysi et al.   NATURE GENETICS

Various cross-linking methods inhibit the collagenase I degradation of rabbit scleral tissue

(2020) Konstantin Krasselt et al.   BMC Ophthalmology

Myopia

(2020) Paul N. Baird et al.   Nature Reviews Disease Primers

Scleral structure and biomechanics

(2019) Craig Boote et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Smurf2, an E3 ubiquitin ligase, interacts with PDE4B and attenuates liver fibrosis through miR-132 mediated CTGF inhibition

(2018) Yu Cai et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error

(2018) Milly S. Tedja et al.   NATURE GENETICS

Complications of Pathologic Myopia

(2016) Bum-Joo Cho et al.   Eye & Contact Lens-Science and Clinical Practice

Global Prevalence of Myopia and High Myopia and Temporal Trends from 2000 through 2050

(2016) Brien A. Holden et al.   OPHTHALMOLOGY

Increasing Prevalence of Myopia in Europe and the Impact of Education

(2015) Katie M. Williams et al.   OPHTHALMOLOGY

Investigating mechanisms of myopia in mice

(2013) Machelle T. Pardue et al.   EXPERIMENTAL EYE RESEARCH

cAMP Level Modulates Scleral Collagen Remodeling, a Critical Step in the Development of Myopia

(2013) Yijin Tao et al.   PLoS One

Variational analysis of the mouse and rat eye optical parameters

(2013) Gurinder Bawa et al.   Biomedical Optics Express

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

cAMP and Epac in the regulation of tissue fibrosis

(2012) Paul A Insel et al.   BRITISH JOURNAL OF PHARMACOLOGY

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

The differential impact of PDE4 subtypes in human lung fibroblasts on cytokine-induced proliferation and myofibroblast conversion

(2010) Jens Selige et al.   JOURNAL OF CELLULAR PHYSIOLOGY

PDE4 inhibitors roflumilast and rolipram augment PGE2 inhibition of TGF-β1-stimulated fibroblasts

(2009) Shinsaku Togo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Increased cAMP Levels Modulate Transforming Growth Factor-β/Smad-induced Expression of Extracellular Matrix Components and Other Key Fibroblast Effector Functions

(2009) Meinhard Schiller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt

(2009) Steffen Durinck et al.   Nature Protocols

Biometric measurement of the mouse eye using optical coherence tomography with focal plane advancement

(2008) Xiangtian Zhou et al.   VISION RESEARCH