CLEC12B suppresses lung cancer progression by inducing SHP-1 expression and inactivating the PI3K/AKT signaling pathway

Small in Size, but Large in Action: microRNAs as Potential Modulators of PTEN in Breast and Lung Cancers

(2021) Asal Jalal Abadi et al.   Biomolecules

Therapeutic potential of AMPK signaling targeting in lung cancer: Advances, challenges and future prospects

(2021) Milad Ashrafizadeh et al.   LIFE SCIENCES

KIR3DL3-HHLA2 is a human immunosuppressive pathway and a therapeutic target

(2021) Yao Wei et al.   Science Immunology

Inhibition of SHP-1 expands the repertoire of antitumor T cells available to respond to immune checkpoint blockade

(2020) Jeremy P. Snook et al.   Cancer Immunology Research

Targeted Therapy for Non-Small Cell Lung Cancer

(2020) Zorawar S. Noor et al.   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

Versatile role of curcumin and its derivatives in lung cancer therapy

(2020) Milad Ashrafizadeh et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Porcine CLEC12B is expressed on alveolar macrophages and blood dendritic cells

(2020) Elvira Nieto-Pelegrín et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Collagen promotes anti-PD-1/PD-L1 resistance in cancer through LAIR1-dependent CD8+ T cell exhaustion

(2020) David H. Peng et al.   Nature Communications

Lung cancer

(2020) Herb Brody   NATURE

Lung cancer cells and their sensitivity/resistance to cisplatin chemotherapy: Role of microRNAs and upstream mediators

(2020) Milad Ashrafizadeh et al.   CELLULAR SIGNALLING

Cancer statistics, 2019

(2019) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

The potential role of miR‐29 in health and cancer diagnosis, prognosis, and therapy

(2019) Mohsen Alizadeh et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Mcl-1 Interacts with Akt to Promote Lung Cancer Progression

(2019) Guo Chen et al.   CANCER RESEARCH

C‐type lectin receptors of the Dectin‐1 cluster: Physiological roles and involvement in disease

(2019) Kazuya Tone et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

SHP-1 acts as a Tumor Suppressor in Hepatocarcinogenesis and HCC Progression

(2018) Liang-Zhi Wen et al.   CANCER RESEARCH

MicroRNA in lung cancer: role, mechanisms, pathways and therapeutic relevance

(2018) Mohammad Askandar Iqbal et al.   MOLECULAR ASPECTS OF MEDICINE

Inhibition of STAT3 in gastric cancer: role of pantoprazole as SHP-1 inducer

(2018) Jin Sung Koh et al.   Cell and Bioscience

DCUN1D1 facilitates tumor metastasis by activating FAK signaling and up-regulates PD-L1 in non-small-cell lung cancer

(2018) Jing Li et al.   EXPERIMENTAL CELL RESEARCH

Pinpointing a potential role for CLEC12B in cancer predisposition through familial exome sequencing

(2018) Charlotte Derpoorter et al.   PEDIATRIC BLOOD & CANCER

Lung cancer: current therapies and new targeted treatments

(2017) Fred R Hirsch et al.   LANCET

SHP-1 is a negative regulator of epithelial-mesenchymal transition in hepatocellular carcinoma

(2017) L-C Fan et al.   ONCOGENE

SHP-1: the next checkpoint target for cancer immunotherapy?

(2016) H. Angharad Watson et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Targeting PI3K/AKT/mTOR pathway in non small cell lung cancer

(2014) Claudia Fumarola et al.   BIOCHEMICAL PHARMACOLOGY

Signal Transducer and Activator of Transcription 3 as Molecular Therapy for Non–Small-Cell Lung Cancer

(2014) Cheng-Yi Wang et al.   Journal of Thoracic Oncology

Realizing the promise of cancer predisposition genes

(2014) Nazneen Rahman   NATURE

Differential proteomic analysis of caveolin-1 KO cells reveals Sh2b3 and Clec12b as novel interaction partners of caveolin-1 and Capns1 as a potential mediator of caveolin-1-induced apoptosis

(2013) Yogesh M. Kulkarni et al.   ANALYST

SHP1-mediated cell cycle redistribution inhibits radiosensitivity of non-small cell lung cancer

(2013) Rubo Cao et al.   Radiation Oncology

Non-Small Cell Lung Cancer: Epidemiology, Risk Factors, Treatment, and Survivorship

(2012) Julian R. Molina et al.   MAYO CLINIC PROCEEDINGS

Signaling Networks Associated with AKT Activation in Non-Small Cell Lung Cancer (NSCLC): New Insights on the Role of Phosphatydil-Inositol-3 kinase

(2012) Marianna Scrima et al.   PLoS One

SHP-1 expression accounts for resistance to imatinib treatment in Philadelphia chromosome-positive cells derived from patients with chronic myeloid leukemia

(2011) N. Esposito et al.   BLOOD

Src Homology Domain 2-containing Protein-tyrosine Phosphatase-1 (SHP-1) Binds and Dephosphorylates Gα-interacting, Vesicle-associated Protein (GIV)/Girdin and Attenuates the GIV-Phosphatidylinositol 3-Kinase (PI3K)-Akt Signaling Pathway

(2011) Yash Mittal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Knockdown of protein tyrosine phosphatase SHP-1 inhibits G1/S progression in prostate cancer cells through the regulation of components of the cell-cycle machinery

(2009) F J Rodríguez-Ubreva et al.   ONCOGENE