Signaling Networks Associated with AKT Activation in Non-Small Cell Lung Cancer (NSCLC): New Insights on the Role of Phosphatydil-Inositol-3 kinase

Oncogenic Role of the E3 Ubiquitin Ligase NEDD4-1, a PTEN Negative Regulator, in Non-Small-Cell Lung Carcinomas

(2010) Nicola Amodio et al.   AMERICAN JOURNAL OF PATHOLOGY

Activating E17K mutation in the gene encoding the protein kinase AKT in a subset of squamous cell carcinoma of the lung

(2010) Donatella Malanga et al.   CELL CYCLE

Increased expression of Akt2 and activity of PI3K and cell proliferation with the ascending of tumor grade of human gliomas

(2010) Guangxiu Wang et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

PIKing the right isoform: the emergent role of the p110β subunit in breast cancer

(2010) Silvia Carvalho et al.   VIRCHOWS ARCHIV

Up-regulation of PIK3CA promotes metastasis in gastric carcinoma

(2010) Ji-Fang Liu   WORLD JOURNAL OF GASTROENTEROLOGY

Phosphatidylinositol-3-Kinase as a Therapeutic Target in Melanoma

(2009) S. A. Aziz et al.   CLINICAL CANCER RESEARCH

The Role of the Akt/mTOR Pathway in Tobacco Carcinogen-Induced Lung Tumorigenesis

(2009) R. M. Memmott et al.   CLINICAL CANCER RESEARCH

The PKB/AKT Pathway in Cancer

(2009) Amancio Carnero   CURRENT PHARMACEUTICAL DESIGN

Molecular alterations inAKT1,AKT2andAKT3detected in breast and prostatic cancer by FISH

(2009) Tove Kirkegaard et al.   HISTOPATHOLOGY

PTEN Expression and KRAS Mutations on Primary Tumors and Metastases in the Prediction of Benefit From Cetuximab Plus Irinotecan for Patients With Metastatic Colorectal Cancer

(2009) Fotios Loupakis et al.   JOURNAL OF CLINICAL ONCOLOGY

PIK3CA alterations in Middle Eastern ovarian cancers

(2009) Jehad Abubaker et al.   Molecular Cancer

Alterations in Genes of the EGFR Signaling Pathway and Their Relationship to EGFR Tyrosine Kinase Inhibitor Sensitivity in Lung Cancer Cell Lines

(2009) Jeet Gandhi et al.   PLoS One

PTEN and the PI3-Kinase Pathway in Cancer

(2008) Nader Chalhoub et al.   Annual Review of Pathology-Mechanisms of Disease

Cancer Statistics, 2008

(2008) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

An Integrative Genomic and Proteomic Analysis of PIK3CA, PTEN, and AKT Mutations in Breast Cancer

(2008) K. Stemke-Hale et al.   CANCER RESEARCH

PIK3CA Mutations and Copy Number Gains in Human Lung Cancers

(2008) H. Yamamoto et al.   CANCER RESEARCH

Frequent mutations and amplifications of the PIK3CA gene in pituitary tumors

(2008) Yong Lin et al.   ENDOCRINE-RELATED CANCER

Akt2 overexpression plays a critical role in the establishment of colorectal cancer metastasis

(2008) P. G. Rychahou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA