Expression of activator proteins of SHH/GLI and PI3K/Akt/mTORC1 signaling pathways in human gliomas is associated with high grade tumors
出版年份 2021 全文链接
标题
Expression of activator proteins of SHH/GLI and PI3K/Akt/mTORC1 signaling pathways in human gliomas is associated with high grade tumors
作者
关键词
SHH, GLI, Akt, S6K1, cell signaling, glioma
出版物
EXPERIMENTAL AND MOLECULAR PATHOLOGY
Volume 122, Issue -, Pages 104673
出版商
Elsevier BV
发表日期
2021-08-08
DOI
10.1016/j.yexmp.2021.104673
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Cortical Neural Stem Cell Lineage Progression Is Regulated by Extrinsic Signaling Molecule Sonic Hedgehog
- (2020) Yue Zhang et al. Cell Reports
- Low PTEN expression and overexpression of phosphorylated AktSer473 and AktThr308 are associated with poor overall survival in upper tract urothelial carcinoma
- (2020) Wen-Hui Weng et al. Oncology Letters
- Abnormal activity of transcription factors gli in high-grade gliomas
- (2019) Andrey Volnitskiy et al. PLoS One
- Intra-Tumoral Metabolic Zonation and Resultant Phenotypic Diversification Are Dictated by Blood Vessel Proximity
- (2019) Saran Kumar et al. Cell Metabolism
- Multiple roles of Sonic Hedgehog in the developing human cortex are suggested by its widespread distribution
- (2018) Fani Memi et al. Brain Structure & Function
- Inhibition of sonic hedgehog and PI3K/Akt/mTOR pathways cooperate in suppressing survival, self-renewal and tumorigenic potential of glioblastoma-initiating cells
- (2018) Rajesh Nanta et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Smoothened is a poor prognosis factor and a potential therapeutic target in glioma
- (2017) Yiming Tu et al. Scientific Reports
- The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary
- (2016) David N. Louis et al. ACTA NEUROPATHOLOGICA
- PI3K–mTOR Pathway Inhibition Exhibits Efficacy Against High-grade Glioma in Clinically Relevant Mouse Models
- (2016) Fan Lin et al. CLINICAL CANCER RESEARCH
- Neurons diversify astrocytes in the adult brain through sonic hedgehog signaling
- (2016) W. T. Farmer et al. SCIENCE
- PI3K/Akt/mTOR signaling pathway and targeted therapy for glioblastoma
- (2016) Xiaoman Li et al. Oncotarget
- Sonic hedgehog stimulates neurite outgrowth in a mechanical stretch model of reactive-astrogliosis
- (2016) Antonio Berretta et al. Scientific Reports
- The S6K protein family in health and disease
- (2015) Mariana R. Tavares et al. LIFE SCIENCES
- Oligodendrocyte Development and Plasticity
- (2015) Dwight E. Bergles et al. Cold Spring Harbor Perspectives in Biology
- Hedgehog Signaling Pathway Is Active in GBM with GLI1 mRNA Expression Showing a Single Continuous Distribution Rather than Discrete High/Low Clusters
- (2015) Vikas Chandra et al. PLoS One
- The SHH/Gli pathway is reactivated in reactive glia and drives proliferation in response to neurodegeneration-induced lesions
- (2014) Kenneth L. Pitter et al. GLIA
- Endothelial cells promote stem-like phenotype of glioma cells through activating the Hedgehog pathway
- (2014) Guang-Ning Yan et al. JOURNAL OF PATHOLOGY
- Targeting Class IA PI3K Isoforms Selectively Impairs Cell Growth, Survival, and Migration in Glioblastoma
- (2014) Katrin Höland et al. PLoS One
- Sonic hedgehog signaling in the postnatal brain
- (2014) Arturo Álvarez-Buylla et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- The Somatic Genomic Landscape of Glioblastoma
- (2013) Cameron W. Brennan et al. CELL
- Gli3 Regulation of Myogenesis Is Necessary for Ischemia-Induced Angiogenesis
- (2013) Marie-Ange Renault et al. CIRCULATION RESEARCH
- Therapeutic targeting of EGFR-activated metabolic pathways in glioblastoma
- (2013) Qinglei Gao et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- The integrated landscape of driver genomic alterations in glioblastoma
- (2013) Veronique Frattini et al. NATURE GENETICS
- Coordinate activation of Shh and PI3K signaling in PTEN-deficient glioblastoma: new therapeutic opportunities
- (2013) Mariella Gruber Filbin et al. NATURE MEDICINE
- Malignant Glioma: Lessons from Genomics, Mouse Models, and Stem Cells
- (2012) Jian Chen et al. CELL
- The mTOR Signalling Pathway in Human Cancer
- (2012) Helena Pópulo et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Fiji: an open-source platform for biological-image analysis
- (2012) Johannes Schindelin et al. NATURE METHODS
- Essential role of the Hedgehog signaling pathway in human glioma-initiating cells
- (2011) Tatsuya Takezaki et al. CANCER SCIENCE
- Role of sonic hedgehog signaling in migration of cell lines established from CD133-positive malignant glioma cells
- (2011) Hiroyuki Uchida et al. JOURNAL OF NEURO-ONCOLOGY
- PTEN, NHERF1 and PHLPP form a tumor suppressor network that is disabled in glioblastoma
- (2011) J R Molina et al. ONCOGENE
- The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence
- (2011) J. I. Alvarez et al. SCIENCE
- PI3K/AKT pathway alterations are associated with clinically aggressive and histologically anaplastic subsets of pilocytic astrocytoma
- (2010) Erika F. Rodriguez et al. ACTA NEUROPATHOLOGICA
- Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1
- (2010) Roel G.W. Verhaak et al. CANCER CELL
- Hedgehog/GLI1 regulates IGF dependent malignant behaviors in glioma stem cells
- (2010) Antony Hsieh et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Dual blocking of mTor and PI3K elicits a prodifferentiation effect on glioblastoma stem-like cells
- (2010) Jun Sunayama et al. NEURO-ONCOLOGY
- Sonic Hedgehog/GLI1 signaling pathway inhibition restricts cell migration and invasion in human gliomas
- (2010) Ke Wang et al. NEUROLOGICAL RESEARCH
- PTEN/PI3K/Akt Pathway Regulates the Side Population Phenotype and ABCG2 Activity in Glioma Tumor Stem-like Cells
- (2009) Anne-Marie Bleau et al. Cell Stem Cell
- The Hedgehog Transcription Factor Gli3 Modulates Angiogenesis
- (2009) Marie-Ange Renault et al. CIRCULATION RESEARCH
- Turning Cancer Stem Cells Inside Out: An Exploration of Glioma Stem Cell Signaling Pathways
- (2009) Zhizhong Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Gli1 inhibition induces cell-cycle arrest and enhanced apoptosis in brain glioma cell lines
- (2009) Ke Wang et al. JOURNAL OF NEURO-ONCOLOGY
- Sonic Hedgehog Pathway Activation Is Induced by Acute Brain Injury and Regulated by Injury-Related Inflammation
- (2009) N. M. Amankulor et al. JOURNAL OF NEUROSCIENCE
- Gli1 is a potential target for alleviating multidrug resistance of gliomas
- (2009) Daming Cui et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Targeted inhibition of the Hedgehog pathway in established malignant glioma xenografts enhances survival
- (2009) A Sarangi et al. ONCOGENE
- S6K1 Plays a Key Role in Glial Transformation
- (2008) J. L. Nakamura et al. CANCER RESEARCH
- Gli Activity Correlates with Tumor Grade in Platelet-Derived Growth Factor-Induced Gliomas
- (2008) O. J. Becher et al. CANCER RESEARCH
- APE1/Ref-1 regulates PTEN expression mediated by Egr-1
- (2008) Damiano Fantini et al. FREE RADICAL RESEARCH
- Comprehensive genomic characterization defines human glioblastoma genes and core pathways
- (2008) Roger McLendon et al. NATURE
- An Integrated Genomic Analysis of Human Glioblastoma Multiforme
- (2008) D. W. Parsons et al. SCIENCE
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