Endothelial cells promote stem-like phenotype of glioma cells through activating the Hedgehog pathway

Bmi1 Is Required for Hedgehog Pathway-Driven Medulloblastoma Expansion

(2015) Lowell Evan Michael et al.   NEOPLASIA

Endothelial Cells Promote the Colorectal Cancer Stem Cell Phenotype through a Soluble Form of Jagged-1

(2013) Jia Lu et al.   CANCER CELL

The Cancer Diaspora: Metastasis beyond the Seed and Soil Hypothesis

(2013) K. J. Pienta et al.   CLINICAL CANCER RESEARCH

Functional Role of CLIC1 Ion Channel in Glioblastoma-Derived Stem/Progenitor Cells

(2013) Matteo Setti et al.   JNCI-Journal of the National Cancer Institute

The perivascular niche regulates breast tumour dormancy

(2013) Cyrus M. Ghajar et al.   NATURE CELL BIOLOGY

Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas

(2012) Marcel Kool et al.   ACTA NEUROPATHOLOGICA

The metastatic niche and stromal progression

(2012) Jonathan P. Sleeman   CANCER AND METASTASIS REVIEWS

Perivascular stem cell niche in head and neck cancer

(2012) Kathryn E. Ritchie et al.   CANCER LETTERS

Identification of Hedgehog pathway responsive glioblastomas by isocitrate dehydrogenase mutation

(2012) J. Gerardo Valadez et al.   CANCER LETTERS

Hedgehog regulates angiogenesis of intersegmental vessels through the VEGF signaling pathway

(2012) Carlos M. Moran et al.   DEVELOPMENTAL DYNAMICS

Therapeutic targeting of VEGF in the treatment of glioblastoma

(2012) Lizbeth Robles Irizarry et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

CXCL12/CXCR4 Protein Signaling Axis Induces Sonic Hedgehog Expression in Pancreatic Cancer Cells via Extracellular Regulated Kinase- and Akt Kinase-mediated Activation of Nuclear Factor κB

(2012) Ajay P. Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Determining Mammosphere-Forming Potential: Application of the Limiting Dilution Analysis

(2012) Lauren M. Rota et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations

(2012) Trevor J. Pugh et al.   NATURE

Self-Renewal and Pluripotency Acquired through Somatic Reprogramming to Human Cancer Stem Cells

(2012) Shogo Nagata et al.   PLoS One

Notch signaling contributes to the maintenance of both normal neural stem cells and patient-derived glioma stem cells

(2011) Yi-Yang Hu et al.   BMC CANCER

Endothelial Cells Create a Stem Cell Niche in Glioblastoma by Providing NOTCH Ligands That Nurture Self-Renewal of Cancer Stem-Like Cells

(2011) T. S. Zhu et al.   CANCER RESEARCH

Cancer Stem Cell Niche: The Place to Be

(2011) T. Borovski et al.   CANCER RESEARCH

Essential role of the Hedgehog signaling pathway in human glioma-initiating cells

(2011) Tatsuya Takezaki et al.   CANCER SCIENCE

The chemokine CXCL12 and its receptor CXCR4 promote glioma stem cell-mediated VEGF production and tumour angiogenesis via PI3K/AKT signalling

(2011) Yi-fang Ping et al.   JOURNAL OF PATHOLOGY

Sonic hedgehog regulates Bmi1 in human medulloblastoma brain tumor-initiating cells

(2011) X Wang et al.   ONCOGENE

Regulation of sonic hedgehog-GLI1 downstream target genes PTCH1, Cyclin D2, Plakoglobin, PAX6 and NKX2.2 and their epigenetic status in medulloblastoma and astrocytoma

(2010) Mehdi H Shahi et al.   BMC CANCER

A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2α

(2010) Sascha Seidel et al.   BRAIN

Cancer stem cells in solid tumors: elusive or illusive?

(2010) Yvonne Welte et al.   Cell Communication and Signaling

Oncogene-induced plasticity and cancer stem cells

(2010) Ulf R. Rapp et al.   CELL CYCLE

The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype

(2010) John M. Heddleston et al.   CELL CYCLE

Perivascular Nitric Oxide Activates Notch Signaling and Promotes Stem-like Character in PDGF-Induced Glioma Cells

(2010) Nikki Charles et al.   Cell Stem Cell

Cancer Stem Cells and Self-renewal

(2010) C. A. O'Brien et al.   CLINICAL CANCER RESEARCH

Overexpression and Gender-specific Differences of SRC-3 (SRC-3/AIB1) Immunoreactivity in Human Non-Small Cell Lung Cancer: An In Vivo Study

(2010) Haidong Wang et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

CD133+ niches and single cells in glioblastoma have different phenotypes

(2010) Karina Christensen et al.   JOURNAL OF NEURO-ONCOLOGY

Inhibition of Notch Signaling in Glioblastoma Targets Cancer Stem Cells via an Endothelial Cell Intermediate

(2010) Koos E. Hovinga et al.   STEM CELLS

Cancer stem cells in glioblastoma—molecular signaling and therapeutic targeting

(2010) Zhi Huang et al.   Protein & Cell

Glioblastoma and endothelial cells cross-talk, mediated by SDF-1, enhances tumour invasion and endothelial proliferation by increasing expression of cathepsins B, S, and MMP-9

(2009) Saša Kenig et al.   CANCER LETTERS

Glioma Tumor Stem-Like Cells Promote Tumor Angiogenesis and Vasculogenesis via Vascular Endothelial Growth Factor and Stromal-Derived Factor 1

(2009) C. Folkins et al.   CANCER RESEARCH

Immune-Induced Epithelial to Mesenchymal Transition In vivo Generates Breast Cancer Stem Cells

(2009) M. Santisteban et al.   CANCER RESEARCH

Cancer stem cells and their niche

(2009) Hiroko Iwasaki et al.   CANCER SCIENCE

Cancer stem cells: mirage or reality?

(2009) Piyush B Gupta et al.   NATURE MEDICINE

Targeted inhibition of the Hedgehog pathway in established malignant glioma xenografts enhances survival

(2009) A Sarangi et al.   ONCOGENE

Gli Activity Correlates with Tumor Grade in Platelet-Derived Growth Factor-Induced Gliomas

(2008) O. J. Becher et al.   CANCER RESEARCH

Characterization of sonic hedgehog as a novel NF-κB target gene that promotes NF-κB-mediated apoptosis resistance and tumor growth in vivo

(2008) Hubert Kasperczyk et al.   FASEB JOURNAL

PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo

(2008) D. Hambardzumyan et al.   GENES & DEVELOPMENT

Relationship of neural stem cells with their vascular niche: Implications in the malignant progression of gliomas

(2008) Kaveh Barami   JOURNAL OF CLINICAL NEUROSCIENCE

A paracrine requirement for hedgehog signalling in cancer

(2008) Robert L. Yauch et al.   NATURE

Hedgehog Signaling Regulates Brain Tumor-Initiating Cell Proliferation and Portends Shorter Survival for Patients with PTEN-Coexpressing Glioblastomas

(2008) Qijin Xu et al.   STEM CELLS