标题
DNA hypomethylation leads to cGAS‐induced autoinflammation in the epidermis
作者
关键词
-
出版物
EMBO JOURNAL
Volume 40, Issue 22, Pages -
出版商
EMBO
发表日期
2021-09-30
DOI
10.15252/embj.2021108234
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Zebularine elevates STING expression and enhances cGAMP cancer immunotherapy in mice
- (2021) Junzhong Lai et al. MOLECULAR THERAPY
- Analysis of Methylation Dynamics Reveals a Tissue-Specific, Age-Dependent Decline in 5-Methylcytosine Within the Genome of the Vertebrate Aging Model Nothobranchius furzeri
- (2021) Gordin Zupkovitz et al. Frontiers in Molecular Biosciences
- Sensing of endogenous nucleic acids by ZBP1 induces keratinocyte necroptosis and skin inflammation
- (2020) Michael Devos et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation
- (2020) Huipeng Jiao et al. NATURE
- Old dogs, new trick: classic cancer therapies activate cGAS
- (2020) Seoyun Yum et al. CELL RESEARCH
- Immune Sensing Mechanisms that Discriminate Self from Altered Self and Foreign Nucleic Acids
- (2020) Eva Bartok et al. IMMUNITY
- Pharmacologic induction of innate immune signaling directly drives homologous recombination deficiency
- (2020) Lena J. McLaughlin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- cGAS-STING pathway in oncogenesis and cancer therapeutics
- (2020) Brandon Yi Da Hoong et al. Oncotarget
- Type I Interferonopathies: from a Novel Concept to Targeted Therapeutics
- (2020) Isabelle Melki et al. Current Rheumatology Reports
- Epigenetic therapy induces transcription of inverted SINEs and ADAR1 dependency
- (2020) Parinaz Mehdipour et al. NATURE
- Targeting the epigenetic regulation of antitumour immunity
- (2020) Simon J. Hogg et al. NATURE REVIEWS DRUG DISCOVERY
- Self-Awareness: Nucleic Acid–Driven Inflammation and the Type I Interferonopathies
- (2019) Carolina Uggenti et al. Annual Review of Immunology
- LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation
- (2019) Matthew Simon et al. Cell Metabolism
- Epigenetic gene regulation, chromatin structure, and force-induced chromatin remodelling in epidermal development and homeostasis
- (2019) Yekaterina A Miroshnikova et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- The Dynamics of the Skin’s Immune System
- (2019) Alan V. Nguyen et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- STING pathway agonism as a cancer therapeutic
- (2019) Blake A. Flood et al. IMMUNOLOGICAL REVIEWS
- Regulation of cGAS- and RLR-mediated immunity to nucleic acids
- (2019) Andrea Ablasser et al. NATURE IMMUNOLOGY
- The Cytosolic DNA-Sensing cGAS–STING Pathway in Cancer
- (2019) John Kwon et al. Cancer Discovery
- Hypomethylating agents in combination with immune checkpoint inhibitors in acute myeloid leukemia and myelodysplastic syndromes
- (2018) Naval Daver et al. LEUKEMIA
- Chromosomal instability drives metastasis through a cytosolic DNA response
- (2018) Samuel F. Bakhoum et al. NATURE
- Targeting STING with covalent small-molecule inhibitors
- (2018) Simone M. Haag et al. NATURE
- Establishment of keratinocyte cell lines from human hair follicles
- (2018) Tanja Wagner et al. Scientific Reports
- A noncanonical function of cGAMP in inflammasome priming and activation
- (2017) Karen V. Swanson et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Dynamics and Context-Dependent Roles of DNA Methylation
- (2017) Christina Ambrosi et al. JOURNAL OF MOLECULAR BIOLOGY
- cGAS surveillance of micronuclei links genome instability to innate immunity
- (2017) Karen J. Mackenzie et al. NATURE
- Cytoplasmic chromatin triggers inflammation in senescence and cancer
- (2017) Zhixun Dou et al. NATURE
- Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence
- (2017) Selene Glück et al. NATURE CELL BIOLOGY
- Genetic and Epigenetic Determinants in Autoinflammatory Diseases
- (2017) Damiana Álvarez-Errico et al. Frontiers in Immunology
- Recognition of Endogenous Nucleic Acids by the Innate Immune System
- (2016) Axel Roers et al. IMMUNITY
- Methyltransferase Dnmt3a upregulates HDAC9 to deacetylate the kinase TBK1 for activation of antiviral innate immunity
- (2016) Xia Li et al. NATURE IMMUNOLOGY
- Targeting the cancer epigenome for therapy
- (2016) Peter A. Jones et al. NATURE REVIEWS GENETICS
- DNA demethylation caused by 5-Aza-2’-deoxycytidine induces mitotic alterations and aneuploidy
- (2016) Giuseppe Costa et al. Oncotarget
- DNA Methylation Inhibitors in Cancer Therapy: The Immunity Dimension
- (2015) Jonathan D. Licht CELL
- DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts
- (2015) David Roulois et al. CELL
- Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses
- (2015) Katherine B. Chiappinelli et al. CELL
- Dnmt1 is essential to maintain progenitors in the perinatal intestinal epithelium
- (2015) E. N. Elliott et al. DEVELOPMENT
- Positive Feedback Regulation of Type I IFN Production by the IFN-Inducible DNA Sensor cGAS
- (2015) Feng Ma et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: cGAS Is Required for Lethal Autoimmune Disease in the Trex1-Deficient Mouse Model of Aicardi–Goutières Syndrome
- (2015) Elizabeth E. Gray et al. JOURNAL OF IMMUNOLOGY
- Function and information content of DNA methylation
- (2015) Dirk Schübeler NATURE
- Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases
- (2015) Daxing Gao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- HTSeq--a Python framework to work with high-throughput sequencing data
- (2014) S. Anders et al. BIOINFORMATICS
- Transcriptional landscape of repetitive elements in normal and cancer human cells
- (2014) Steven W Criscione et al. BMC GENOMICS
- RNA:DNA hybrids are a novel molecular pattern sensed by TLR9
- (2014) R. E. Rigby et al. EMBO JOURNAL
- DNA methylation is required for the control of stem cell differentiation in the small intestine
- (2014) K. L. Sheaffer et al. GENES & DEVELOPMENT
- An Integrated Epigenetic and Transcriptomic Analysis Reveals Distinct Tissue-Specific Patterns of DNA Methylation Associated with Atopic Dermatitis
- (2014) Elke Rodríguez et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- High-resolution genome-wide DNA methylation maps of mouse primary female dermal fibroblasts and keratinocytes
- (2014) Raghunath Chatterjee et al. Epigenetics & Chromatin
- The RNA-Editing Enzyme ADAR1 Controls Innate Immune Responses to RNA
- (2014) Niamh M. Mannion et al. Cell Reports
- Divergent roles of HDAC1 and HDAC2 in the regulation of epidermal development and tumorigenesis
- (2013) Mircea Winter et al. EMBO JOURNAL
- DNMT1 represses p53 to maintain progenitor cell survival during pancreatic organogenesis
- (2013) S. Georgia et al. GENES & DEVELOPMENT
- Inflammation-mediated skin tumorigenesis induced by epidermal c-Fos
- (2013) E. M. Briso et al. GENES & DEVELOPMENT
- Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity
- (2013) John W. Schoggins et al. NATURE
- DNA methylation: roles in mammalian development
- (2013) Zachary D. Smith et al. NATURE REVIEWS GENETICS
- The characteristics of genome-wide DNA methylation in naïve CD4+ T cells of patients with psoriasis or atopic dermatitis
- (2012) Jihye Han et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Strong induction of AIM2 expression in human epidermis in acute and chronic inflammatory skin conditions
- (2012) Heleen D. de Koning et al. EXPERIMENTAL DERMATOLOGY
- Progressive Alopecia Reveals Decreasing Stem Cell Activation Probability during Aging of Mice with Epidermal Deletion of DNA Methyltransferase 1
- (2012) Ji Li et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- A Role for Epigenetics in Psoriasis: Methylated Cytosine–Guanine Sites Differentiate Lesional from Nonlesional Skin and from Normal Skin
- (2012) Johann E. Gudjonsson et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Fiji: an open-source platform for biological-image analysis
- (2012) Johannes Schindelin et al. NATURE METHODS
- STING manifests self DNA-dependent inflammatory disease
- (2012) J. Ahn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- In Vivo Control of CpG and Non-CpG DNA Methylation by DNA Methyltransferases
- (2012) Julia Arand et al. PLoS Genetics
- FLASH: fast length adjustment of short reads to improve genome assemblies
- (2011) T. Magoc et al. BIOINFORMATICS
- Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity
- (2011) Taro Kawai et al. IMMUNITY
- BiQ Analyzer HT: locus-specific analysis of DNA methylation by high-throughput bisulfite sequencing
- (2011) Pavlo Lutsik et al. NUCLEIC ACIDS RESEARCH
- Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human cells
- (2010) M. Fenech et al. MUTAGENESIS
- DNMT1 maintains progenitor function in self-renewing somatic tissue
- (2010) George L. Sen et al. NATURE
- edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
- (2009) M. D. Robinson et al. BIOINFORMATICS
- DNA methylation and the functional organization of the nuclear compartment
- (2009) Jesús Espada et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
- (2009) Ben Langmead et al. GENOME BIOLOGY
- More than one way to skin . . .
- (2008) E. Fuchs et al. GENES & DEVELOPMENT
- Modes of action of the DNA methyltransferase inhibitors azacytidine and decitabine
- (2008) Carlo Stresemann et al. INTERNATIONAL JOURNAL OF CANCER
- Mapping and quantifying mammalian transcriptomes by RNA-Seq
- (2008) Ali Mortazavi et al. NATURE METHODS
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started