Recent advances in lipid nanoparticles for delivery of nucleic acid, mRNA, and gene editing-based therapeutics
出版年份 2022 全文链接
标题
Recent advances in lipid nanoparticles for delivery of nucleic acid, mRNA, and gene editing-based therapeutics
作者
关键词
Lipid nanoparticle, Nucleic acid, mRNA, Gene editing, Base editing, Ionizable lipid, Targeting, DNA barcode, Recombination, Positron emission tomography
出版物
Drug Metabolism and Pharmacokinetics
Volume -, Issue -, Pages 100450
出版商
Elsevier BV
发表日期
2022-02-05
DOI
10.1016/j.dmpk.2022.100450
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Ionizable lipid nanoparticles for in utero mRNA delivery
- (2021) Rachel S. Riley et al. Science Advances
- In vivo cytidine base editing of hepatocytes without detectable off-target mutations in RNA and DNA
- (2021) Lukas Villiger et al. Nature Biomedical Engineering
- Treatment of influenza and SARS-CoV-2 infections via mRNA-encoded Cas13a in rodents
- (2021) Emmeline L. Blanchard et al. NATURE BIOTECHNOLOGY
- Lipid nanoparticle-mediated codelivery of Cas9 mRNA and single-guide RNA achieves liver-specific in vivo genome editing of Angptl3
- (2021) Min Qiu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Engineered ionizable lipid nanoparticles for targeted delivery of RNA therapeutics into different types of cells in the liver
- (2021) M. Kim et al. Science Advances
- Apolipoprotein E Binding Drives Structural and Compositional Rearrangement of mRNA-Containing Lipid Nanoparticles
- (2021) Federica Sebastiani et al. ACS Nano
- mRNA Delivery of a Bispecific Single‐Domain Antibody to Polarize Tumor‐Associated Macrophages and Synergize Immunotherapy against Liver Malignancies
- (2021) Ying Wang et al. ADVANCED MATERIALS
- Novel approaches for vaccine development
- (2021) Makda S. Gebre et al. CELL
- mRNA-lipid nanoparticle COVID-19 vaccines: Structure and stability
- (2021) Linde Schoenmaker et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates
- (2021) Kiran Musunuru et al. NATURE
- In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels
- (2021) Tanja Rothgangl et al. NATURE BIOTECHNOLOGY
- All‐In‐One Dendrimer‐Based Lipid Nanoparticles Enable Precise HDR‐Mediated Gene Editing In Vivo
- (2021) Lukas Farbiak et al. ADVANCED MATERIALS
- Conformation-sensitive targeting of lipid nanoparticles for RNA therapeutics
- (2021) Niels Dammes et al. Nature Nanotechnology
- The Importance of Apparent pKa in the Development of Nanoparticles Encapsulating siRNA and mRNA
- (2021) Pratikkumar Patel et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Different kinetics for the hepatic uptake of lipid nanoparticles between the apolipoprotein E/low density lipoprotein receptor and the N-acetyl-d-galactosamine/asialoglycoprotein receptor pathway
- (2020) Yusuke Sato et al. JOURNAL OF CONTROLLED RELEASE
- ImmunoPET: Concept, Design, and Applications
- (2020) Weijun Wei et al. CHEMICAL REVIEWS
- Directed evolution of adenine base editors with increased activity and therapeutic application
- (2020) Nicole M. Gaudelli et al. NATURE BIOTECHNOLOGY
- Selective organ targeting (SORT) nanoparticles for tissue-specific mRNA delivery and CRISPR–Cas gene editing
- (2020) Qiang Cheng et al. Nature Nanotechnology
- Development of lipid-like materials for RNA delivery based on intracellular environment-responsive membrane destabilization and spontaneous collapse
- (2020) Hiroki Tanaka et al. ADVANCED DRUG DELIVERY REVIEWS
- Lipid nanoparticles for nucleic acid delivery: Current perspectives
- (2020) Eleni Samaridou et al. ADVANCED DRUG DELIVERY REVIEWS
- Lipid nanoparticle technology for therapeutic gene regulation in the liver
- (2020) Dominik Witzigmann et al. ADVANCED DRUG DELIVERY REVIEWS
- The Biomolecular Corona of Lipid Nanoparticles for Gene Therapy
- (2020) Valentina Francia et al. BIOCONJUGATE CHEMISTRY
- A Thermostable mRNA Vaccine against COVID-19
- (2020) Na-Na Zhang et al. CELL
- The delivery challenge: fulfilling the promise of therapeutic genome editing
- (2020) Joost van Haasteren et al. NATURE BIOTECHNOLOGY
- COVID-19 vaccine development and a potential nanomaterial path forward
- (2020) Matthew D. Shin et al. Nature Nanotechnology
- Review: PET imaging with macro- and middle-sized molecular probes
- (2020) Hidefumi Mukai et al. NUCLEAR MEDICINE AND BIOLOGY
- Systemic nanoparticle delivery of CRISPR-Cas9 ribonucleoproteins for effective tissue specific genome editing
- (2020) Tuo Wei et al. Nature Communications
- Increased PIP3 activity blocks nanoparticle mRNA delivery
- (2020) Kalina Paunovska et al. Science Advances
- Neurotransmitter-derived lipidoids (NT-lipidoids) for enhanced brain delivery through intravenous injection
- (2020) Feihe Ma et al. Science Advances
- Dual mRNA therapy restores metabolic function in long-term studies in mice with propionic acidemia
- (2020) Lei Jiang et al. Nature Communications
- Development of a gene-editing approach to restore vision loss in Leber congenital amaurosis type 10
- (2019) Morgan L. Maeder et al. NATURE MEDICINE
- Durable anticancer immunity from intratumoral administration of IL-23, IL-36γ, and OX40L mRNAs
- (2019) Susannah L. Hewitt et al. Science Translational Medicine
- Delivering the Messenger: Advances in Technologies for Therapeutic mRNA Delivery
- (2019) Piotr S. Kowalski et al. MOLECULAR THERAPY
- MRNA Delivery For Therapeutic Anti-Her2 Antibody Expression In Vivo
- (2019) Yulia Rybakova et al. MOLECULAR THERAPY
- Macrocyclic peptide-based inhibition and imaging of hepatocyte growth factor
- (2019) Katsuya Sakai et al. Nature Chemical Biology
- Optimization of Lipid Nanoparticles for Intramuscular Administration of mRNA Vaccines
- (2019) Kimberly J. Hassett et al. Molecular Therapy-Nucleic Acids
- Visualization of early events in mRNA vaccine delivery in non-human primates via PET–CT and near-infrared imaging
- (2019) Kevin E. Lindsay et al. Nature Biomedical Engineering
- Fast and Efficient CRISPR/Cas9 Genome Editing In Vivo Enabled by Bioreducible Lipid and Messenger RNA Nanoparticles
- (2019) Ji Liu et al. ADVANCED MATERIALS
- Mannosylation of LNP Results in Improved Potency for Self-Amplifying RNA (SAM) Vaccines
- (2019) Roshan Goswami et al. ACS Infectious Diseases
- A lipid-encapsulated mRNA encoding a potently neutralizing human monoclonal antibody protects against chikungunya infection
- (2019) Nurgun Kose et al. Science Immunology
- Lipid Nanoparticle Technology for Clinical Translation of siRNA Therapeutics
- (2019) Jayesh A. Kulkarni et al. ACCOUNTS OF CHEMICAL RESEARCH
- Rational designs of in vivo CRISPR-Cas delivery systems
- (2019) Cong-Fei Xu et al. ADVANCED DRUG DELIVERY REVIEWS
- Mild Innate Immune Activation Overrides Efficient Nanoparticle‐Mediated RNA Delivery
- (2019) Melissa P. Lokugamage et al. ADVANCED MATERIALS
- Ionizable lipid nanoparticles encapsulating barcoded mRNA for accelerated in vivo delivery screening
- (2019) Pedro P.G. Guimaraes et al. JOURNAL OF CONTROLLED RELEASE
- Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency
- (2019) David N. Nguyen et al. NATURE BIOTECHNOLOGY
- The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs
- (2019) Akin Akinc et al. Nature Nanotechnology
- Advances in microfluidics for lipid nanoparticles and extracellular vesicles and applications in drug delivery systems
- (2018) Masatoshi Maeki et al. ADVANCED DRUG DELIVERY REVIEWS
- Delivering CRISPR: a review of the challenges and approaches
- (2018) Christopher A. Lino et al. DRUG DELIVERY
- Structure of Lipid Nanoparticles Containing siRNA or mRNA by Dynamic Nuclear Polarization-Enhanced NMR Spectroscopy
- (2018) Jasmine Viger-Gravel et al. JOURNAL OF PHYSICAL CHEMISTRY B
- A modular platform for targeted RNAi therapeutics
- (2018) Ranit Kedmi et al. Nature Nanotechnology
- Successful reprogramming of cellular protein production through mRNA delivered by functionalized lipid nanoparticles
- (2018) Marianna Yanez Arteta et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Single-cell bioluminescence imaging of deep tissue in freely moving animals
- (2018) Satoshi Iwano et al. SCIENCE
- A Single Administration of CRISPR/Cas9 Lipid Nanoparticles Achieves Robust and Persistent In Vivo Genome Editing
- (2018) Jonathan D. Finn et al. Cell Reports
- Modifying a Commonly Expressed Endocytic Receptor Retargets Nanoparticles in Vivo
- (2018) Cory D. Sago et al. NANO LETTERS
- CRISPR-Cas guides the future of genetic engineering
- (2018) Gavin J. Knott et al. SCIENCE
- Pharmacokinetic evaluation of liposomal nanoparticle-encapsulated nucleic acid drug: A combined study of dynamic PET imaging and LC/MS/MS analysis
- (2018) Hidefumi Mukai et al. JOURNAL OF CONTROLLED RELEASE
- Treatment of a metabolic liver disease by in vivo genome base editing in adult mice
- (2018) Lukas Villiger et al. NATURE MEDICINE
- Base editing: precision chemistry on the genome and transcriptome of living cells
- (2018) Holly A. Rees et al. NATURE REVIEWS GENETICS
- Cell specific delivery of modified mRNA expressing therapeutic proteins to leukocytes
- (2018) Nuphar Veiga et al. Nature Communications
- Delivery strategies of the CRISPR-Cas9 gene-editing system for therapeutic applications
- (2017) Chang Liu et al. JOURNAL OF CONTROLLED RELEASE
- Lipid Nanoparticle Systems for Enabling Gene Therapies
- (2017) Pieter R. Cullis et al. MOLECULAR THERAPY
- RNA targeting with CRISPR–Cas13
- (2017) Omar O. Abudayyeh et al. NATURE
- Delivery technologies for genome editing
- (2017) Hao Yin et al. NATURE REVIEWS DRUG DISCOVERY
- Barcoded nanoparticles for high throughput in vivo discovery of targeted therapeutics
- (2017) James E. Dahlman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Systemic delivery of factor IX messenger RNA for protein replacement therapy
- (2017) Suvasini Ramaswamy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nucleic acid detection with CRISPR-Cas13a/C2c2
- (2017) Jonathan S. Gootenberg et al. SCIENCE
- Administration of nucleoside-modified mRNA encoding broadly neutralizing antibody protects humanized mice from HIV-1 challenge
- (2017) Norbert Pardi et al. Nature Communications
- Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
- (2016) Alexis C. Komor et al. NATURE
- Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo
- (2016) Hao Yin et al. NATURE BIOTECHNOLOGY
- Efficient delivery of genome-editing proteins using bioreducible lipid nanoparticles
- (2016) Ming Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems
- (2016) K. Nishida et al. SCIENCE
- C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector
- (2016) Omar O. Abudayyeh et al. SCIENCE
- A luciferin analogue generating near-infrared bioluminescence achieves highly sensitive deep-tissue imaging
- (2016) Takahiro Kuchimaru et al. Nature Communications
- Fc-Binding Ligands of Immunoglobulin G: An Overview of High Affinity Proteins and Peptides
- (2016) Weonu Choe et al. Materials
- Systemic Gene Silencing in Primary T Lymphocytes Using Targeted Lipid Nanoparticles
- (2015) Srinivas Ramishetti et al. ACS Nano
- Expression kinetics of nucleoside-modified mRNA delivered in lipid nanoparticles to mice by various routes
- (2015) Norbert Pardi et al. JOURNAL OF CONTROLLED RELEASE
- Optimization of Lipid Nanoparticle Formulations for mRNA Delivery in Vivo with Fractional Factorial and Definitive Screening Designs
- (2015) Kevin J. Kauffman et al. NANO LETTERS
- Selection-Based Discovery of Druglike Macrocyclic Peptides
- (2014) Toby Passioura et al. Annual Review of Biochemistry
- Glycosylation-mediated targeting of carriers
- (2014) Shigeru Kawakami et al. JOURNAL OF CONTROLLED RELEASE
- Quantitative evaluation of the improvement in the pharmacokinetics of a nucleic acid drug delivery system by dynamic PET imaging with 18F-incorporated oligodeoxynucleotides
- (2014) Hidefumi Mukai et al. JOURNAL OF CONTROLLED RELEASE
- The new frontier of genome engineering with CRISPR-Cas9
- (2014) J. A. Doudna et al. SCIENCE
- Genetic Approaches to Neural Circuits in the Mouse
- (2013) Z. Josh Huang et al. Annual Review of Neuroscience
- The Polyethyleneglycol Dilemma: Advantage and Disadvantage of PEGylation of Liposomes for Systemic Genes and Nucleic Acids Delivery to Tumors
- (2013) Hiroto Hatakeyama et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- mRNA display: from basic principles to macrocycle drug discovery
- (2013) Kristopher Josephson et al. DRUG DISCOVERY TODAY
- Genome engineering using the CRISPR-Cas9 system
- (2013) F Ann Ran et al. Nature Protocols
- RNA-Guided Human Genome Engineering via Cas9
- (2013) P. Mali et al. SCIENCE
- Multiplex Genome Engineering Using CRISPR/Cas Systems
- (2013) L. Cong et al. SCIENCE
- ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering
- (2013) Thomas Gaj et al. TRENDS IN BIOTECHNOLOGY
- A Neutral Envelope-Type Nanoparticle Containing pH-Responsive and SS-Cleavable Lipid-Like Material as a Carrier for Plasmid DNA
- (2013) Hidetaka Akita et al. Advanced Healthcare Materials
- Influence of Polyethylene Glycol Lipid Desorption Rates on Pharmacokinetics and Pharmacodynamics of siRNA Lipid Nanoparticles
- (2013) Barbara L Mui et al. Molecular Therapy-Nucleic Acids
- Maximizing the Potency of siRNA Lipid Nanoparticles for Hepatic Gene Silencing In Vivo
- (2012) Muthusamy Jayaraman et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- A review of glycosylated carriers for drug delivery
- (2012) Keerti Jain et al. BIOMATERIALS
- Lineage Tracing
- (2012) Kai Kretzschmar et al. CELL
- Lipid Nanoparticles Containing siRNA Synthesized by Microfluidic Mixing Exhibit an Electron-Dense Nanostructured Core
- (2012) Alex K. K. Leung et al. Journal of Physical Chemistry C
- Bottom-Up Design and Synthesis of Limit Size Lipid Nanoparticle Systems with Aqueous and Triglyceride Cores Using Millisecond Microfluidic Mixing
- (2012) Igor V. Zhigaltsev et al. LANGMUIR
- Nuclear ribosomal internal transcribed spacer (ITS) region as a universal DNA barcode marker for Fungi
- (2012) C. L. Schoch et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Microfluidic Synthesis of Highly Potent Limit-size Lipid Nanoparticles for In Vivo Delivery of siRNA
- (2012) Nathan M Belliveau et al. Molecular Therapy-Nucleic Acids
- High-Throughput Droplet Digital PCR System for Absolute Quantitation of DNA Copy Number
- (2011) Benjamin J. Hindson et al. ANALYTICAL CHEMISTRY
- PET Imaging of the Gastrointestinal Absorption of Orally Administered Drugs in Conscious and Anesthetized Rats
- (2011) S. Yamashita et al. JOURNAL OF NUCLEAR MEDICINE
- Developmental Changes in P-Glycoprotein Function in the Blood-Brain Barrier of Nonhuman Primates: PET Study with R-11C-Verapamil and 11C-Oseltamivir
- (2011) T. Takashima et al. JOURNAL OF NUCLEAR MEDICINE
- Therapeutic siRNA silencing in inflammatory monocytes in mice
- (2011) Florian Leuschner et al. NATURE BIOTECHNOLOGY
- Impact of microdosing clinical study — Why necessary and how useful?
- (2010) Yuichi Sugiyama et al. ADVANCED DRUG DELIVERY REVIEWS
- A multifunctional envelope type nano device (MEND) for gene delivery to tumours based on the EPR effect: A strategy for overcoming the PEG dilemma
- (2010) Hiroto Hatakeyama et al. ADVANCED DRUG DELIVERY REVIEWS
- Stoichiometry-focused 18F-labeling of alkyne-substituted oligodeoxynucleotides using azido([18F]fluoromethyl)benzenes by Cu-catalyzed Huisgen reaction
- (2010) Takeshi Kuboyama et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Targeted Delivery of RNAi Therapeutics With Endogenous and Exogenous Ligand-Based Mechanisms
- (2010) Akin Akinc et al. MOLECULAR THERAPY
- Rational design of cationic lipids for siRNA delivery
- (2010) Sean C Semple et al. NATURE BIOTECHNOLOGY
- Lipid-like materials for low-dose, in vivo gene silencing
- (2010) K. T. Love et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A robust and high-throughput Cre reporting and characterization system for the whole mouse brain
- (2009) Linda Madisen et al. NATURE NEUROSCIENCE
- Pharmacokinetics and Biodistribution of Nanoparticles
- (2008) Shyh-Dar Li et al. MOLECULAR PHARMACEUTICS
- Nonviral approaches for targeted delivery of plasmid DNA and oligonucleotide
- (2007) Shigeru Kawakami et al. JOURNAL OF PHARMACEUTICAL SCIENCES
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