Molecular characterization of HEK293 cells as emerging versatile cell factories

Author Correction: Evolution from adherent to suspension: systems biology of HEK293 cell line development

(2021) Magdalena Malm et al.   Scientific Reports

Virus Like Particles (VLP) as multivalent vaccine candidate against Chikungunya, Japanese Encephalitis, Yellow Fever and Zika Virus

(2020) Himanshu Garg et al.   Scientific Reports

Development of Magoh protein‐overexpressing HEK cells for optimized therapeutic protein production

(2020) Eduardo F. Mufarrege et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Engineered transient and stable overexpression of translation factors eIF3i and eIF3c in CHOK1 and HEK293 cells gives enhanced cell growth associated with increased c-Myc expression and increased recombinant protein synthesis

(2020) Anne Roobol et al.   METABOLIC ENGINEERING

Comprehensive Analysis of Genomic Safe Harbors as Target Sites for Stable Expression of the Heterologous Gene in HEK293 Cells

(2020) Seunghyeon Shin et al.   ACS Synthetic Biology

Overexpression of ER Protein Processing and Apoptosis Regulator Genes in Human Embryonic Kidney 293 Cells Improves Gene Therapy Vectors Production

(2020) Ana S. Formas‐Oliveira et al.   Biotechnology Journal

Effects of doxorubicin and docetaxel on susceptibility to apoptosis in high expression level of survivin in HEK and HEK-S cell lines as in vitro models

(2020) Kayhan Mehdizadeh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Molecular Characterization of the Coproduced Extracellular Vesicles in HEK293 during Virus-Like Particle Production

(2020) Jesús Lavado-García et al.   JOURNAL OF PROTEOME RESEARCH

Creation of a High-Yield AAV Vector Production Platform in Suspension Cells Using a Design-of-Experiment Approach

(2020) Huiren Zhao et al.   Molecular Therapy-Methods & Clinical Development

Comprehensive characterization of dihydrofolate reductase‐mediated gene amplification for the establishment of recombinant human embryonic kidney 293 cells producing monoclonal antibodies

(2020) Sang Yoon Lee et al.   Biotechnology Journal

The lightning-fast quest for COVID vaccines — and what it means for other diseases

(2020) Philip Ball   NATURE

The CAG promoter maintains high‐level transgene expression in HEK293 cells

(2020) Yuanyuan Dou et al.   FEBS Open Bio

Rapid Lentiviral Vector Producer Cell Line Generation Using a Single DNA Construct

(2020) Yu Hua Chen et al.   Molecular Therapy-Methods & Clinical Development

Establishment of DHFR-deficient HEK293 cells for high yield of therapeutic glycoproteins

(2019) Emmanuel Osei Mensah et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Transient lentiviral vector production using a packed-bed bioreactor system

(2019) Alexandra McCarron et al.   Human Gene Therapy Methods

Gene Therapy Leaves a Vicious Cycle

(2019) Reena Goswami et al.   Frontiers in Oncology

Enabling HEK293 cells for antibiotic-free media bioprocessing through CRISPR/Cas9 gene editing

(2019) Ramon Roman Roldan   BIOCHEMICAL ENGINEERING JOURNAL

Characterization of influenza H1N1 Gag virus-like particles and extracellular vesicles co-produced in HEK-293SF

(2019) Alina Venereo-Sánchez et al.   VACCINE

Zika virus-like particles (VLPs): Stable cell lines and continuous perfusion processes as a new potential vaccine manufacturing platform

(2019) Renata G.F. Alvim et al.   VACCINE

Production of rVSV-ZEBOV in serum-free suspension culture of HEK 293SF cells

(2019) Jean-François Gélinas et al.   VACCINE

A human expression system based on HEK293 for the stable production of recombinant erythropoietin

(2019) Christine Lin Chin et al.   Scientific Reports

Lentiviral Vector Production Titer Is Not Limited in HEK293T by Induced Intracellular Innate Immunity

(2019) Carolina B. Ferreira et al.   Molecular Therapy-Methods & Clinical Development

Glutamine synthetase gene knockout-human embryonic kidney 293E cells for stable production of monoclonal antibodies

(2018) Da Young Yu et al.   BIOTECHNOLOGY AND BIOENGINEERING

Glycoengineering in CHO Cells: Advances in Systems Biology

(2018) Vijay Tejwani et al.   Biotechnology Journal

Human Embryonic Kidney 293 Cells: A Vehicle for Biopharmaceutical Manufacturing, Structural Biology, and Electrophysiology

(2018) Jianwen Hu et al.   CELLS TISSUES ORGANS

Glycoengineering in CHO Cells: Advances in Systems Biology

(2018) Vijay Tejwani et al.   Biotechnology Journal

Enhanced Production of Exosome-Associated AAV by Overexpression of the Tetraspanin CD9

(2018) Lara Timantra Schiller et al.   Molecular Therapy-Methods & Clinical Development

Erratum to: MiR-9-5p Down-Regulates PiT2, but not PiT1 in Human Embryonic Kidney 293 Cells

(2017) D. P. Bezerra et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Process intensification for high yield production of influenza H1N1 Gag virus-like particles using an inducible HEK-293 stable cell line

(2017) Alina Venereo-Sanchez et al.   VACCINE

Identifying HIPK1 as Target of miR-22-3p Enhancing Recombinant Protein Production From HEK 293 Cell by Using Microarray and HTP siRNA Screen

(2017) Sarah Inwood et al.   Biotechnology Journal

Cloning of CHO Cells, Productivity and Genetic Stability—A Discussion

(2017) Florian Wurm et al.   Processes

Viral vaccines and their manufacturing cell substrates: New trends and designs in modern vaccinology

(2015) Ana F. Rodrigues et al.   Biotechnology Journal

Human cell lines for biopharmaceutical manufacturing: history, status, and future perspectives

(2015) Jennifer Dumont et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

Viral vaccines and their manufacturing cell substrates: New trends and designs in modern vaccinology

(2015) Ana F. Rodrigues et al.   Biotechnology Journal

CHO Quasispecies—Implications for Manufacturing Processes

(2013) Florian Wurm   Processes