Nanozymes: Activity origin, catalytic mechanism, and biological application

Single‐Atom Catalysts in Catalytic Biomedicine

(2020) Huijing Xiang et al.   ADVANCED MATERIALS

Specific “Unlocking” Nanozyme-based Butterfly Effect for Breaking the Evolutionary Fitness of Chaotic Tumor

(2020) Wenyao Zhen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nanozymes for medical biotechnology and its potential applications in biosensing and nanotherapeutics

(2020) Samman Munir et al.   BIOTECHNOLOGY LETTERS

GSH-triggered sequential catalysis for tumor imaging and eradication based on star-like Au/Pt enzyme carrier system

(2020) Amin Zhang et al.   Nano Research

Chiral Carbon Dots Mimicking Topoisomerase I To Mediate the Topological Rearrangement of Supercoiled DNA Enantioselectively

(2020) Feng Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Iridium/ruthenium nanozyme reactors with cascade catalytic ability for synergistic oxidation therapy and starvation therapy in the treatment of breast cancer

(2020) Chunfang Wei et al.   BIOMATERIALS

Ultrasmall Rhodium Nanozyme with RONS Scavenging and Photothermal Activities for Anti-Inflammation and Antitumor Theranostics of Colon Diseases

(2020) Zhaohua Miao et al.   NANO LETTERS

MOF-encapsulated nanozyme enhanced siRNA combo: Control neural stem cell differentiation and ameliorate cognitive impairments in Alzheimer's disease model

(2020) Dongqin Yu et al.   BIOMATERIALS

Nano-Apples and Orange-Zymes

(2020) Susannah Scott et al.   ACS Catalysis

Hollow Prussian Blue Nanozymes Drive Neuroprotection against Ischemic Stroke via Attenuating Oxidative Stress, Counteracting Inflammation, and Suppressing Cell Apoptosis

(2019) Kai Zhang et al.   NANO LETTERS

Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications

(2019) Yanyan Huang et al.   CHEMICAL REVIEWS

Porous platinum nanoparticles as a high-Z and oxygen generating nanozyme for enhanced radiotherapy in vivo

(2019) Yan Li et al.   BIOMATERIALS

Chiral Semiconductor Nanoparticles for Protein Catalysis and Profiling

(2019) Changlong Hao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Mechanisms of Nanozymes and Their Applications in Biomedicine

(2019) Haijiao Dong et al.   BIOCONJUGATE CHEMISTRY

Reactive Oxygen Species (ROS)-Based Nanomedicine

(2019) Bowen Yang et al.   CHEMICAL REVIEWS

Intelligent Hollow Pt-CuS Janus Architecture for Synergistic Catalysis-Enhanced Sonodynamic and Photothermal Cancer Therapy

(2019) Shuang Liang et al.   NANO LETTERS

A series of MOF/Ce-based nanozymes with dual enzyme-like activity disrupting biofilms and hindering recolonization of bacteria

(2019) Zhengwei Liu et al.   BIOMATERIALS

Carbogenic Nanozyme with Ultrahigh Reactive Nitrogen Species Selectivity for Traumatic Brain Injury

(2019) Xiaoyu Mu et al.   NANO LETTERS

Biomimetic Hybrid Nanozymes with Self-Supplied H+ and Accelerated O2 Generation for Enhanced Starvation and Photodynamic Therapy against Hypoxic Tumors

(2019) Xue Yang et al.   NANO LETTERS

Surface treatments on titanium implants via nanostructured ceria for antibacterial and anti-inflammatory capabilities

(2019) Xue Li et al.   Acta Biomaterialia

Optimization of Antibacterial Efficacy of Noble-Metal-Based Core–Shell Nanostructures and Effect of Natural Organic Matter

(2019) Tingting Cai et al.   ACS Nano

Enhanced Tumor Synergistic Therapy by Injectable Magnetic Hydrogel Mediated Generation of Hyperthermia and Highly Toxic Reactive Oxygen Species

(2019) Haoan Wu et al.   ACS Nano

Efficient Bacteria Killing by Cu2WS4 Nanocrystals with Enzyme-like Properties and Bacteria-Binding Ability

(2019) Jingyang Shan et al.   ACS Nano

A Nanozyme with Photo-Enhanced Dual Enzyme-Like Activities for Deep Pancreatic Cancer Therapy

(2019) Shanshan Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper/Carbon Hybrid Nanozyme: Tuning Catalytic Activity by the Copper State for Antibacterial Therapy

(2019) Juqun Xi et al.   NANO LETTERS

Mitochondria-targeted TPP-MoS2 with dual enzyme activity provides efficient neuroprotection through M1/M2 microglial polarization in an Alzheimer's disease model

(2019) Chaoxiu Ren et al.   BIOMATERIALS

Tumor Catalytic–Photothermal Therapy with Yolk–Shell Gold@Carbon Nanozymes

(2018) Lei Fan et al.   ACS Applied Materials & Interfaces

Nanozyme Decorated Metal–Organic Frameworks for Enhanced Photodynamic Therapy

(2018) Yan Zhang et al.   ACS Nano

BSA-IrO2 : Catalase-like Nanoparticles with High Photothermal Conversion Efficiency and a High X-ray Absorption Coefficient for Anti-inflammation and Antitumor Theranostics

(2018) Wenyao Zhen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nanoisozymes: Crystal-Facet-Dependent Enzyme-Mimetic Activity of V2 O5 Nanomaterials

(2018) Sourav Ghosh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Albumin coated copper-cysteine nanozyme for reducing oxidative stress induced during sperm cryopreservation

(2018) Fariba Dashtestani et al.   BIOORGANIC CHEMISTRY

Nanoparticle-triggered in situ catalytic chemical reactions for tumour-specific therapy

(2018) Han Lin et al.   CHEMICAL SOCIETY REVIEWS

Scavenging of reactive oxygen and nitrogen species with nanomaterials

(2018) Carolina A. Ferreira et al.   Nano Research

The enzyme-like catalytic activity of cerium oxide nanoparticles and its dependency on Ce3+ surface area concentration

(2018) V. Baldim et al.   Nanoscale

Site-selective photoinduced cleavage and profiling of DNA by chiral semiconductor nanoparticles

(2018) Maozhong Sun et al.   Nature Chemistry

Nanozyme: An emerging alternative to natural enzyme for biosensing and immunoassay

(2018) Qingqing Wang et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

ROS scavenging Mn3O4 nanozymes for in vivo anti-inflammation

(2018) Jia Yao et al.   Chemical Science

Heterogeneous Nanostructure Design Based on the Epitaxial Growth of Spongy MoSx on 2D Co(OH)2 Nanoflakes for Triple-Enzyme Mimetic Activity: Experimental and Density Functional Theory Studies on the Dramatic Activation Mechanism

(2018) Yongqi Ding et al.   ACS Applied Materials & Interfaces

Iridium nanocrystals encapsulated liposomes as near-infrared light controllable nanozymes for enhanced cancer radiotherapy

(2018) Liangzhu Feng et al.   BIOMATERIALS

Engineered nanoceria cytoprotection in vivo: mitigation of reactive oxygen species and double-stranded DNA breakage due to radiation exposure

(2018) Soumen Das et al.   Nanoscale

Synergistic Nanozymetic Activity of Hybrid Gold Bipyramid–Molybdenum Disulfide Core@Shell Nanostructures for Two-Photon Imaging and Anticancer Therapy

(2018) Swarup Kumar Maji et al.   ACS Applied Materials & Interfaces

Chiral Molecule-mediated Porous CuxO Nanoparticle Clusters with Antioxidation Activity for Ameliorating Parkinson’s Disease

(2018) Changlong Hao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Redox-dependent catalase mimetic cerium oxide-based nanozyme protect human hepatic cells from 3-AT induced acatalasemia

(2018) Ragini Singh et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Comprehensive Insights into the Multi-Antioxidative Mechanisms of Melanin Nanoparticles and Their Application To Protect Brain from Injury in Ischemic Stroke

(2017) Yanlan Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecular Imprinting on Inorganic Nanozymes for Hundred-fold Enzyme Specificity

(2017) Zijie Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A bimetallic (Co/2Fe) metal-organic framework with oxidase and peroxidase mimicking activity for colorimetric detection of hydrogen peroxide

(2017) Haiguan Yang et al.   MICROCHIMICA ACTA

Enhanced Cisplatin Chemotherapy by Iron Oxide Nanocarrier-Mediated Generation of Highly Toxic Reactive Oxygen Species

(2017) Ping’an Ma et al.   NANO LETTERS

Smart textiles of MOF/g-C3N4 nanospheres for the rapid detection/detoxification of chemical warfare agents

(2017) Dimitrios A. Giannakoudakis et al.   Nanoscale Horizons

Ceria/POMs hybrid nanoparticles as a mimicking metallopeptidase for treatment of neurotoxicity of amyloid-β peptide

(2016) Yijia Guan et al.   BIOMATERIALS

Prussian Blue Nanoparticles as Multienzyme Mimetics and Reactive Oxygen Species Scavengers

(2016) Wei Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Switching Apoptosis to Ferroptosis: Metal–Organic Network for High-Efficiency Anticancer Therapy

(2016) Di-Wei Zheng et al.   NANO LETTERS

Shape design of cerium oxide nanoparticles for enhancement of enzyme mimetic activity in therapeutic applications

(2016) Tamaki Naganuma   Nano Research

Polyoxometalate-based nanozyme: Design of a multifunctional enzyme for multi-faceted treatment of Alzheimer’s disease

(2016) Nan Gao et al.   Nano Research

Cancer Cell Detection and Therapeutics Using Peroxidase-Active Nanohybrid of Gold Nanoparticle-Loaded Mesoporous Silica-Coated Graphene

(2015) Swarup Kumar Maji et al.   ACS Applied Materials & Interfaces

Deciphering a Nanocarbon-Based Artificial Peroxidase: Chemical Identification of the Catalytically Active and Substrate-Binding Sites on Graphene Quantum Dots

(2015) Hanjun Sun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanism of pH-switchable peroxidase and catalase-like activities of gold, silver, platinum and palladium

(2015) Junnan Li et al.   BIOMATERIALS

Mechanisms of Oxidase and Superoxide Dismutation-like Activities of Gold, Silver, Platinum, and Palladium, and Their Alloys: A General Way to the Activation of Molecular Oxygen

(2015) Xiaomei Shen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly efficient conversion of superoxide to oxygen using hydrophilic carbon clusters

(2015) Errol L. G. Samuel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-site trinuclear copper oxygen clusters in mordenite for selective conversion of methane to methanol

(2015) Sebastian Grundner et al.   Nature Communications

Co3O4 Nanoparticles with Multi-Enzyme Activities and Their Application in Immunohistochemical Assay

(2014) Jinlai Dong et al.   ACS Applied Materials & Interfaces

Molybdenum Trioxide Nanoparticles with Intrinsic Sulfite Oxidase Activity

(2014) Ruben Ragg et al.   ACS Nano

Membrane lipid peroxidation by the peroxidase-like activity of magnetite nanoparticles

(2014) Lijun Wang et al.   CHEMICAL COMMUNICATIONS

Molecular-Level Insights into Intrinsic Peroxidase-Like Activity of Nanocarbon Oxides

(2014) Ruisheng Zhao et al.   CHEMISTRY-A EUROPEAN JOURNAL

An antioxidant nanozyme that uncovers the cytoprotective potential of vanadia nanowires

(2014) Amit A. Vernekar et al.   Nature Communications

Advanced oxidation using Fe3O4 magnetic nanoparticles and its application in mercury speciation analysis by high performance liquid chromatography-cold vapor generation atomic fluorescence spectrometry

(2013) Xi Ai et al.   ANALYST

Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes

(2013) Hui Wei et al.   CHEMICAL SOCIETY REVIEWS

Silica Decorated TiO2 for Virus Inactivation in Drinking Water – Simple Synthesis Method and Mechanisms of Enhanced Inactivation Kinetics

(2013) Michael V. Liga et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Co3O4 nanoparticles as an efficient catalase mimic: Properties, mechanism and its electrocatalytic sensing application for hydrogen peroxide

(2013) Jianshuai Mu et al.   JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL

Wound Dressings and Comparative Effectiveness Data

(2013) Aditya Sood et al.   Advances in Wound Care

Dual Enzyme-like Activities of Iron Oxide Nanoparticles and Their Implication for Diminishing Cytotoxicity

(2012) Zhongwen Chen et al.   ACS Nano

Intrinsic peroxidase-like activity and catalase-like activity of Co3O4 nanoparticles

(2012) Jianshuai Mu et al.   CHEMICAL COMMUNICATIONS

Humic acid coated Fe3O4 magnetic nanoparticles as highly efficient Fenton-like catalyst for complete mineralization of sulfathiazole

(2011) Hongyun Niu et al.   JOURNAL OF HAZARDOUS MATERIALS

Pharmacological potential of cerium oxide nanoparticles

(2011) Ivana Celardo et al.   Nanoscale

Graphene Oxide: Intrinsic Peroxidase Catalytic Activity and Its Application to Glucose Detection

(2010) Yujun Song et al.   ADVANCED MATERIALS

Nanoceria exhibit redox state-dependent catalase mimetic activity

(2010) Talib Pirmohamed et al.   CHEMICAL COMMUNICATIONS

A geometrically nonlinear finite element model of nanomaterials with consideration of surface effects

(2009) Hui She et al.   FINITE ELEMENTS IN ANALYSIS AND DESIGN

The role of cerium redox state in the SOD mimetic activity of nanoceria

(2008) Eric G. Heckert et al.   BIOMATERIALS