Mechanisms of Sinoatrial Node Dysfunction in Heart Failure With Preserved Ejection Fraction

Sex differences in the incidence and mode of death in rats with heart failure with preserved ejection fraction

(2021) Khaled Elkholey et al.   EXPERIMENTAL PHYSIOLOGY

NAD + Repletion Reverses Heart Failure with Preserved Ejection Fraction

(2021) Dan Tong et al.   CIRCULATION RESEARCH

Xbp1s-FoxO1 axis governs lipid accumulation and contractile performance in heart failure with preserved ejection fraction

(2021) Gabriele G. Schiattarella et al.   Nature Communications

How to diagnose heart failure with preserved ejection fraction: the HFA–PEFF diagnostic algorithm: a consensus recommendation from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC)

(2020) Burkert Pieske et al.   EUROPEAN JOURNAL OF HEART FAILURE

Mechanisms of atrial fibrillation in aged rats with heart failure with preserved ejection fraction

(2020) Thassio Ricardo Ribeiro Mesquita et al.   HEART RHYTHM

Research Priorities for Heart Failure With Preserved Ejection Fraction

(2020) Sanjiv J. Shah et al.   CIRCULATION

Mechanisms of Chronotropic Incompetence in Heart Failure With Preserved Ejection Fraction

(2020) Satyam Sarma et al.   Circulation-Heart Failure

Transcriptome analysis of mouse and human sinoatrial node cells reveals a conserved genetic program

(2019) Vincent W. W. van Eif et al.   DEVELOPMENT

Novel functions of macrophages in the heart: insights into electrical conduction, stress, and diastolic dysfunction

(2019) Florian Leuschner et al.   EUROPEAN HEART JOURNAL

Exercise Intolerance in Patients With Heart Failure

(2019) Marco Giuseppe Del Buono et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Nitrosative stress drives heart failure with preserved ejection fraction

(2019) Gabriele G. Schiattarella et al.   NATURE

Transcriptomic Profiling of the Developing Cardiac Conduction System at Single-Cell Resolution

(2019) William R. Goodyer et al.   CIRCULATION RESEARCH

Female Sex Is Protective in a Preclinical Model of Heart Failure With Preserved Ejection Fraction

(2019) Dan Tong et al.   CIRCULATION

Beneficial effects of ivabradine in patients with heart failure, low ejection fraction, and heart rate above 77 b.p.m.

(2019) Nadia Bouabdallaoui et al.   ESC Heart Failure

Heterogeneity of calcium clock functions in dormant, dysrhythmically and rhythmically firing single pacemaker cells isolated from SA node

(2018) Mary S. Kim et al.   CELL CALCIUM

A Simple, Evidence-Based Approach to Help Guide Diagnosis of Heart Failure with Preserved Ejection Fraction

(2018) Yogesh N. V. Reddy et al.   CIRCULATION

Ventricular Arrhythmias Underlie Sudden Death in Rats With Heart Failure and Preserved Ejection Fraction

(2018) Jae Hyung Cho et al.   Circulation-Arrhythmia and Electrophysiology

Exercise unmasks distinct pathophysiologic features in heart failure with preserved ejection fraction and pulmonary vascular disease

(2018) Thomas M Gorter et al.   EUROPEAN HEART JOURNAL

A coupled-clock system drives the automaticity of human sinoatrial nodal pacemaker cells

(2018) Kenta Tsutsui et al.   Science Signaling

A coupled-clock system drives the automaticity of human sinoatrial nodal pacemaker cells

(2018) Kenta Tsutsui et al.   Science Signaling

Chronotropic Incompetence in Chronic Heart Failure

(2018) Alwin Zweerink et al.   Circulation-Heart Failure

Effect of ivabradine in patients with heart failure with preserved ejection fraction: the EDIFY randomized placebo-controlled trial

(2017) Michel Komajda et al.   EUROPEAN JOURNAL OF HEART FAILURE

Computational analysis of the human sinus node action potential: model development and effects of mutations

(2017) Alan Fabbri et al.   JOURNAL OF PHYSIOLOGY-LONDON

Mode of Death in Heart Failure With Preserved Ejection Fraction

(2017) Muthiah Vaduganathan et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Next-generation pacemakers: from small devices to biological pacemakers

(2017) Eugenio Cingolani et al.   Nature Reviews Cardiology

Redundant and diverse intranodal pacemakers and conduction pathways protect the human sinoatrial node from failure

(2017) Ning Li et al.   Science Translational Medicine

Role of Diastolic Stress Testing in the Evaluation for Heart Failure With Preserved Ejection FractionClinical Perspective

(2016) Masaru Obokata et al.   CIRCULATION

Sinus Node and Atrial Arrhythmias

(2016) Roy M. John et al.   CIRCULATION

Abnormal right ventricular-pulmonary artery coupling with exercise in heart failure with preserved ejection fraction

(2016) Barry A. Borlaug et al.   EUROPEAN HEART JOURNAL

Effect of Selective Heart Rate Slowing in Heart Failure With Preserved Ejection FractionCLINICAL PERSPECTIVE

(2015) Nikhil Pal et al.   CIRCULATION

Burst pacemaker activity of the sinoatrial node in sodium–calcium exchanger knockout mice

(2015) Angelo G. Torrente et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ca2+ cycling properties are conserved despite bradycardic effects of heart failure in sinoatrial node cells

(2015) Arie O. Verkerk et al.   Frontiers in Physiology

Sinoatrial node dysfunction induces cardiac arrhythmias in diabetic mice

(2014) Ewa Soltysinska et al.   Cardiovascular Diabetology

Upregulation of Adenosine A1 Receptors Facilitates Sinoatrial Node Dysfunction in Chronic Canine Heart Failure by Exacerbating Nodal Conduction Abnormalities Revealed by Novel Dual-Sided Intramural Optical Mapping

(2014) Qing Lou et al.   CIRCULATION

Incidence of and Risk Factors for Sick Sinus Syndrome in the General Population

(2014) Paul N. Jensen et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Temporal Relationship and Prognostic Significance of Atrial Fibrillation in Heart Failure Patients With Preserved Ejection Fraction

(2013) Rosita Zakeri et al.   CIRCULATION

Calsequestrin 2 deletion causes sinoatrial node dysfunction and atrial arrhythmias associated with altered sarcoplasmic reticulum calcium cycling and degenerative fibrosis within the mouse atrial pacemaker complex1

(2013) Alexey V. Glukhov et al.   EUROPEAN HEART JOURNAL

Processing and analysis of cardiac optical mapping data obtained with potentiometric dyes

(2012) Jacob I. Laughner et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Paradoxical Effect of Increased Diastolic Ca 2+ Release and Decreased Sinoatrial Node Activity in a Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia

(2012) Patricia Neco et al.   CIRCULATION

Heart rate reduction by If-inhibition improves vascular stiffness and left ventricular systolic and diastolic function in a mouse model of heart failure with preserved ejection fraction

(2012) Jan-Christian Reil et al.   EUROPEAN HEART JOURNAL

An updated computational model of rabbit sinoatrial action potential to investigate the mechanisms of heart rate modulation

(2012) Stefano Severi et al.   JOURNAL OF PHYSIOLOGY-LONDON

Changes in Ion Channel Gene Expression Underlying Heart Failure-Induced Sinoatrial Node Dysfunction

(2011) Joseph Yanni et al.   Circulation-Heart Failure

Oxidized CaMKII causes cardiac sinus node dysfunction in mice

(2011) Paari Dominic Swaminathan et al.   JOURNAL OF CLINICAL INVESTIGATION

Deep bradycardia and heart block caused by inducible cardiac-specific knockout of the pacemaker channel gene Hcn4

(2011) M. Baruscotti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exercise Hemodynamics Enhance Diagnosis of Early Heart Failure With Preserved Ejection Fraction

(2010) Barry A. Borlaug et al.   Circulation-Heart Failure

Structural and Functional Evidence for Discrete Exit Pathways That Connect the Canine Sinoatrial Node and Atria

(2009) Vadim V. Fedorov et al.   CIRCULATION RESEARCH

Genetic analysis of salt-sensitive hypertension in Dahl rats reveals a link between cardiac fibrosis and high cholesterol

(2008) N. Wendt et al.   CARDIOVASCULAR RESEARCH