An updated computational model of rabbit sinoatrial action potential to investigate the mechanisms of heart rate modulation

The case for the funny current and the calcium clock

(2011) Michael R. Rosen et al.   HEART RHYTHM

The funny current in the context of the coupled-clock pacemaker cell system

(2011) Victor A. Maltsev et al.   HEART RHYTHM

The funny current has a major pacemaking role in the sinus node

(2011) Dario DiFrancesco et al.   HEART RHYTHM

Deep bradycardia and heart block caused by inducible cardiac-specific knockout of the pacemaker channel gene Hcn4

(2011) M. Baruscotti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel quantitative explanation for the autonomic modulation of cardiac pacemaker cell automaticity via a dynamic system of sarcolemmal and intracellular proteins

(2010) Victor A. Maltsev et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Minor contribution of cytosolic Ca2+ transients to the pacemaker rhythm in guinea pig sinoatrial node cells

(2010) Yukiko Himeno et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Competing Oscillators in Cardiac Pacemaking

(2010) Denis Noble et al.   CIRCULATION RESEARCH

A Coupled SYSTEM of Intracellular Ca 2+ Clocks and Surface Membrane Voltage Clocks Controls the Timekeeping Mechanism of the Heart’s Pacemaker

(2010) Edward G. Lakatta et al.   CIRCULATION RESEARCH

The Role of the Funny Current in Pacemaker Activity

(2010) Dario DiFrancesco   CIRCULATION RESEARCH

Relative importance of funny current in human versus rabbit sinoatrial node

(2010) Arie O. Verkerk et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Synergism of coupled subsarcolemmal Ca2+ clocks and sarcolemmal voltage clocks confers robust and flexible pacemaker function in a novel pacemaker cell model

(2009) Victor A. Maltsev et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Mechanisms of β-Adrenergic Modulation of IKs in the Guinea-Pig Ventricle: Insights from Experimental and Model-Based Analysis

(2009) Stefano Severi et al.   BIOPHYSICAL JOURNAL

What keeps us ticking: a funny current, a calcium clock, or both?

(2009) Edward G. Lakatta et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

CELLULAR OPEN RESOURCE (COR): current status and future directions

(2009) A. Garny et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

Ionic Mechanisms Underlying the Positive Chronotropy Induced by β1-Adrenergic Stimulation in Guinea Pig Sinoatrial Node Cells: a Simulation Study

(2008) Yukiko Himeno et al.   Journal of Physiological Sciences