Glutamate metabolism directs energetic trade-offs to shape host-pathogen susceptibility in Drosophila
出版年份 2021 全文链接
标题
Glutamate metabolism directs energetic trade-offs to shape host-pathogen susceptibility in Drosophila
作者
关键词
innate immunity, lipid metabolism, muscle, immunometabolism, mitochondria, glutamate, glutamate dehydrogenase, vitamin, Smvt, life history
出版物
Cell Metabolism
Volume 33, Issue 12, Pages 2428-2444.e8
出版商
Elsevier BV
发表日期
2021-10-27
DOI
10.1016/j.cmet.2021.10.003
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Renal Purge of Hemolymphatic Lipids Prevents the Accumulation of ROS-Induced Inflammatory Oxidized Lipids and Protects Drosophila from Tissue Damage
- (2020) Xiaoxue Li et al. IMMUNITY
- Mitochondrial Functions in Infection and Immunity
- (2020) Varnesh Tiku et al. TRENDS IN CELL BIOLOGY
- Systemic Immunometabolism: Challenges and Opportunities
- (2020) Alexander Lercher et al. IMMUNITY
- The Drosophila midgut and the systemic coordination of lipid-dependent energy homeostasis
- (2020) Xiao Zhao et al. Current Opinion in Insect Science
- An evolutionary perspective on immunometabolism
- (2019) Andrew Wang et al. SCIENCE
- Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
- (2019) Abhishek A. Chakraborty et al. SCIENCE
- Energetic Trade-Offs and Hypometabolic States Promote Disease Tolerance
- (2019) Kirthana Ganeshan et al. CELL
- Relaxed Selection Limits Lifespan by Increasing Mutation Load
- (2019) Rongfeng Cui et al. CELL
- Sugar Alcohols of Polyol Pathway Serve as Alarmins to Mediate Local-Systemic Innate Immune Communication in Drosophila
- (2019) Shuo Yang et al. Cell Host & Microbe
- Adult Drosophila Lack Hematopoiesis but Rely on a Blood Cell Reservoir at the Respiratory Epithelia to Relay Infection Signals to Surrounding Tissues
- (2019) Pablo Sanchez Bosch et al. DEVELOPMENTAL CELL
- Inflammation-Modulated Metabolic Reprogramming Is Required for DUOX-Dependent Gut Immunity in Drosophila
- (2018) Kyung-Ah Lee et al. Cell Host & Microbe
- Immune–metabolic interactions during systemic and enteric infection in Drosophila
- (2018) Kyung-Ah Lee et al. Current Opinion in Insect Science
- Metabolic regulation of inflammation
- (2017) Timo Gaber et al. Nature Reviews Rheumatology
- Drosophila muscles regulate the immune response against wasp infection via carbohydrate metabolism
- (2017) Hairu Yang et al. Scientific Reports
- Stochastic variation in the initial phase of bacterial infection predicts the probability of survival in D. melanogaster
- (2017) David Duneau et al. eLife
- Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages
- (2016) Evanna L. Mills et al. CELL
- Genetic Ancestry and Natural Selection Drive Population Differences in Immune Responses to Pathogens
- (2016) Yohann Nédélec et al. CELL
- NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria
- (2016) Zhenyu Zhong et al. CELL
- Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition
- (2016) Marco Sciacovelli et al. NATURE
- S-2-hydroxyglutarate regulates CD8+ T-lymphocyte fate
- (2016) Petros A. Tyrakis et al. NATURE
- TrpA1 Regulates Defecation of Food-Borne Pathogens under the Control of the Duox Pathway
- (2016) Eun Jo Du et al. PLoS Genetics
- NF-κB pathway controls mitochondrial dynamics
- (2015) M Laforge et al. CELL DEATH AND DIFFERENTIATION
- Muscle as a “Mediator” of Systemic Metabolism
- (2015) Kedryn K. Baskin et al. Cell Metabolism
- The Transgenic RNAi Project at Harvard Medical School: Resources and Validation
- (2015) L. A. Perkins et al. GENETICS
- GDH-Dependent Glutamate Oxidation in the Brain Dictates Peripheral Energy Substrate Distribution
- (2015) Melis Karaca et al. Cell Reports
- The Acetate Switch of an Intestinal Pathogen Disrupts Host Insulin Signaling and Lipid Metabolism
- (2014) Saiyu Hang et al. Cell Host & Microbe
- Ret rescues mitochondrial morphology and muscle degeneration of Drosophila Pink1 mutants
- (2014) P. Klein et al. EMBO JOURNAL
- Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells
- (2014) Bryce W. Carey et al. NATURE
- Quantifying Drosophila food intake: comparative analysis of current methodology
- (2014) Sonali A Deshpande et al. NATURE METHODS
- Heterogeneity in immune responses: from populations to single cells
- (2014) Rahul Satija et al. TRENDS IN IMMUNOLOGY
- MEF2 Is an In Vivo Immune-Metabolic Switch
- (2013) Rebecca I. Clark et al. CELL
- Tolerance of Infections
- (2012) Janelle S. Ayres et al. Annual Review of Immunology
- Sodium Dependent Multivitamin Transporter (SMVT): A Potential Target for Drug Delivery
- (2012) Aswani Dutt Vadlapudi et al. CURRENT DRUG TARGETS
- Lipid droplet-based storage fat metabolism inDrosophila: Fig. 1.
- (2012) Ronald P. Kühnlein JOURNAL OF LIPID RESEARCH
- Intestinal barrier dysfunction links metabolic and inflammatory markers of aging to death in Drosophila
- (2012) M. Rera et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lipoproteins in Drosophila melanogaster—Assembly, Function, and Influence on Tissue Lipid Composition
- (2012) Wilhelm Palm et al. PLoS Genetics
- Targeting the motor regulator Klar to lipid droplets
- (2011) Yanxun V Yu et al. BMC CELL BIOLOGY
- Enteric Neurons and Systemic Signals Couple Nutritional and Reproductive Status with Intestinal Homeostasis
- (2011) Paola Cognigni et al. Cell Metabolism
- NF-κB controls energy homeostasis and metabolic adaptation by upregulating mitochondrial respiration
- (2011) Claudio Mauro et al. NATURE CELL BIOLOGY
- Thermal sensitivity of mitochondrial metabolism in two distinct mitotypes of Drosophila simulans: evaluation of mitochondrial plasticity
- (2010) N. Pichaud et al. JOURNAL OF EXPERIMENTAL BIOLOGY
- Lipoprotein Particles Cross the Blood-Brain Barrier in Drosophila
- (2010) M. Brankatschk et al. JOURNAL OF NEUROSCIENCE
- Glutamate joins the ranks of immunomodulators
- (2010) Anna M Hansen et al. NATURE MEDICINE
- CF2 Represses Actin 88F Gene Expression and Maintains Filament Balance during Indirect Flight Muscle Development in Drosophila
- (2010) Kathleen M. Gajewski et al. PLoS One
- ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation
- (2009) K. E. Wellen et al. SCIENCE
- The Role of Anorexia in Resistance and Tolerance to Infections in Drosophila
- (2009) Janelle S. Ayres et al. PLOS BIOLOGY
- Keap1/Nrf2 Signaling Regulates Oxidative Stress Tolerance and Lifespan in Drosophila
- (2008) Gerasimos P. Sykiotis et al. DEVELOPMENTAL CELL
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started