标题
The NSP14/NSP10 RNA repair complex as a Pan-coronavirus therapeutic target
作者
关键词
-
出版物
CELL DEATH AND DIFFERENTIATION
Volume 29, Issue 2, Pages 285-292
出版商
Springer Science and Business Media LLC
发表日期
2021-12-03
DOI
10.1038/s41418-021-00900-1
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Mechanism of SARS-CoV-2 polymerase stalling by remdesivir
- (2021) Goran Kokic et al. Nature Communications
- A comparative analysis of SARS-CoV-2 antivirals characterizes 3CLpro inhibitor PF-00835231 as a potential new treatment for COVID-19
- (2021) Maren de Vries et al. JOURNAL OF VIROLOGY
- Pharmacological review of isobavachalcone, a naturally occurring chalcone
- (2021) Miaojuan Wang et al. PHARMACOLOGICAL RESEARCH
- Crystal structure of SARS-CoV-2 nsp10 bound to nsp14-ExoN domain reveals an exoribonuclease with both structural and functional integrity
- (2021) Sheng Lin et al. NUCLEIC ACIDS RESEARCH
- Label-Free Screening of SARS-CoV-2 NSP14 Exonuclease Activity Using SAMDI Mass Spectrometry
- (2021) Michael D. Scholle et al. SLAS Discovery
- Reconstitution and functional characterization of SARS-CoV-2 proofreading complex
- (2021) Zhijun Ma et al. PROTEIN EXPRESSION AND PURIFICATION
- Remdesivir is a direct-acting antiviral that inhibits RNA-dependent RNA polymerase from severe acute respiratory syndrome coronavirus 2 with high potency
- (2020) Calvin J. Gordon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir
- (2020) Wanchao Yin et al. SCIENCE
- An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice
- (2020) Timothy P. Sheahan et al. Science Translational Medicine
- Remdesivir and SARS-CoV-2: Structural requirements at both nsp12 RdRp and nsp14 Exonuclease active-sites
- (2020) Ashleigh Shannon et al. ANTIVIRAL RESEARCH
- Coronavirus RNA proofreading: molecular basis and therapeutic targeting
- (2020) Fran Robson et al. MOLECULAR CELL
- The enzymatic activity of the nsp14 exoribonuclease is critical for replication of MERS-CoV and SARS-CoV-2
- (2020) Natacha S. Ogando et al. JOURNAL OF VIROLOGY
- The Curious Case of the Nidovirus Exoribonuclease: Its Role in RNA Synthesis and Replication Fidelity
- (2019) Natacha S. Ogando et al. Frontiers in Microbiology
- Small-Molecule Antiviral β-D-N4-Hydroxycytidine Inhibits a Proofreading-Intact Coronavirus with a High Genetic Barrier to Resistance
- (2019) Maria L. Agostini et al. JOURNAL OF VIROLOGY
- Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease
- (2018) Maria L. Agostini et al. mBio
- Structural and molecular basis of mismatch correction and ribavirin excision from coronavirus RNA
- (2017) François Ferron et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural basis and functional analysis of the SARS coronavirus nsp14–nsp10 complex
- (2015) Yuanyuan Ma et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Investigation of a Novel Series of 2-Hydroxyisoquinoline-1,3(2H,4H)-diones as Human Immunodeficiency Virus Type 1 Integrase Inhibitors
- (2014) Virginie Suchaud et al. JOURNAL OF MEDICINAL CHEMISTRY
- Coronaviruses Resistant to a 3C-Like Protease Inhibitor Are Attenuated for Replication and Pathogenesis, Revealing a Low Genetic Barrier but High Fitness Cost of Resistance
- (2014) X. Deng et al. JOURNAL OF VIROLOGY
- 2-Hydroxyisoquinoline-1,3(2H,4H)-diones (HIDs), Novel Inhibitors of HIV Integrase with a High Barrier to Resistance
- (2013) Belete A. Desimmie et al. ACS Chemical Biology
- Coronaviruses Lacking Exoribonuclease Activity Are Susceptible to Lethal Mutagenesis: Evidence for Proofreading and Potential Therapeutics
- (2013) Everett Clinton Smith et al. PLoS Pathogens
- RNA 3'-end mismatch excision by the severe acute respiratory syndrome coronavirus nonstructural protein nsp10/nsp14 exoribonuclease complex
- (2012) M. Bouvet et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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