Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson’s disease
出版年份 2020 全文链接
标题
Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson’s disease
作者
关键词
-
出版物
NATURE GENETICS
Volume 52, Issue 5, Pages 482-493
出版商
Springer Science and Business Media LLC
发表日期
2020-04-28
DOI
10.1038/s41588-020-0610-9
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk
- (2019) Iris E. Jansen et al. NATURE GENETICS
- Identification of common genetic risk variants for autism spectrum disorder
- (2019) Jakob Grove et al. NATURE GENETICS
- Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
- (2019) Brian W. Kunkle et al. NATURE GENETICS
- Defining the Genetic, Genomic, Cellular, and Diagnostic Architectures of Psychiatric Disorders
- (2019) Patrick F. Sullivan et al. CELL
- Genome-wide association study identifies 30 loci associated with bipolar disorder
- (2019) Eli A. Stahl et al. NATURE GENETICS
- Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa
- (2019) Hunna J. Watson et al. NATURE GENETICS
- Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies
- (2019) Mike A Nalls et al. LANCET NEUROLOGY
- Parkinson’s disease from the gut
- (2018) Rodger A. Liddle BRAIN RESEARCH
- Biological annotation of genetic loci associated with intelligence in a meta-analysis of 87,740 individuals
- (2018) Jonathan R. I. Coleman et al. MOLECULAR PSYCHIATRY
- Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
- (2018) Naomi R. Wray et al. NATURE GENETICS
- Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence
- (2018) Jeanne E. Savage et al. NATURE GENETICS
- Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways
- (2018) Mats Nagel et al. NATURE GENETICS
- Genetic identification of brain cell types underlying schizophrenia
- (2018) Nathan G. Skene et al. NATURE GENETICS
- Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes
- (2018) Rainer Malik et al. NATURE GENETICS
- Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
- (2018) Antonio F. Pardiñas et al. NATURE GENETICS
- Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types
- (2018) Hilary K. Finucane et al. NATURE GENETICS
- Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals
- (2018) James J. Lee et al. NATURE GENETICS
- Massively Parallel Single Nucleus Transcriptional Profiling Defines Spinal Cord Neurons and Their Activity during Behavior
- (2018) Anupama Sathyamurthy et al. Cell Reports
- Molecular Diversity and Specializations among the Cells of the Adult Mouse Brain
- (2018) Arpiar Saunders et al. CELL
- Molecular Architecture of the Mouse Nervous System
- (2018) Amit Zeisel et al. CELL
- Meta-analysis of genome-wide association studies for height and body mass index in ∼700000 individuals of European ancestry
- (2018) Loic Yengo et al. HUMAN MOLECULAR GENETICS
- Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder
- (2018) Ditte Demontis et al. NATURE GENETICS
- Genetic effects on gene expression across human tissues
- (2017) François Aguet et al. NATURE
- Integrative single-cell analysis of transcriptional and epigenetic states in the human adult brain
- (2017) Blue B Lake et al. NATURE BIOTECHNOLOGY
- Estimating the causal tissues for complex traits and diseases
- (2017) Halit Ongen et al. NATURE GENETICS
- Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease
- (2017) Katrina M de Lange et al. NATURE GENETICS
- Association analyses based on false discovery rate implicate new loci for coronary artery disease
- (2017) Christopher P Nelson et al. NATURE GENETICS
- Massively parallel single-nucleus RNA-seq with DroNc-seq
- (2017) Naomi Habib et al. NATURE METHODS
- Novel genetic loci associated with hippocampal volume
- (2017) Derrek P. Hibar et al. Nature Communications
- Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis
- (2017) Eleanor Wheeler et al. PLOS MEDICINE
- Parkinson disease
- (2017) Werner Poewe et al. Nature Reviews Disease Primers
- Pathological α-synuclein in gastrointestinal tissues from prodromal Parkinson disease patients
- (2016) Morten Gersel Stokholm et al. ANNALS OF NEUROLOGY
- Erratum: Corrigendum: Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine
- (2016) Padhraig Gormley et al. NATURE GENETICS
- Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis
- (2016) Wouter van Rheenen et al. NATURE GENETICS
- Novel genetic loci underlying human intracranial volume identified through genome-wide association
- (2016) Hieab H H Adams et al. NATURE NEUROSCIENCE
- Neuronal subtypes and diversity revealed by single-nucleus RNA sequencing of the human brain
- (2016) B. B. Lake et al. SCIENCE
- Identification of Vulnerable Cell Types in Major Brain Disorders Using Single Cell Transcriptomes and Expression Weighted Cell Type Enrichment
- (2016) Nathan G. Skene et al. Frontiers in Neuroscience
- Genomics implicates adaptive and innate immunity in Alzheimer's and Parkinson's diseases
- (2016) Sarah A. Gagliano et al. Annals of Clinical and Translational Neurology
- Vagotomy and subsequent risk of Parkinson's disease
- (2015) Elisabeth Svensson et al. ANNALS OF NEUROLOGY
- New genetic loci link adipose and insulin biology to body fat distribution
- (2015) Dmitry Shungin et al. NATURE
- Integrative analysis of 111 reference human epigenomes
- (2015) Anshul Kundaje et al. NATURE
- A global reference for human genetic variation
- (2015) Richard A. Gibbs et al. NATURE
- Partitioning heritability by functional annotation using genome-wide association summary statistics
- (2015) Hilary K Finucane et al. NATURE GENETICS
- Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair
- (2015) Felix R Day et al. NATURE GENETICS
- An atlas of genetic correlations across human diseases and traits
- (2015) Brendan Bulik-Sullivan et al. NATURE GENETICS
- The PsychENCODE project
- (2015) Schahram Akbarian et al. NATURE NEUROSCIENCE
- limma powers differential expression analyses for RNA-sequencing and microarray studies
- (2015) Matthew E. Ritchie et al. NUCLEIC ACIDS RESEARCH
- MAGMA: Generalized Gene-Set Analysis of GWAS Data
- (2015) Christiaan A. de Leeuw et al. PLoS Computational Biology
- Evidence for Immune Response, Axonal Dysfunction and Reduced Endocytosis in the Substantia Nigra in Early Stage Parkinson’s Disease
- (2015) Anke A. Dijkstra et al. PLoS One
- The Brainstem Pathologies of Parkinson's Disease and Dementia with Lewy Bodies
- (2014) Kay Seidel et al. BRAIN PATHOLOGY
- Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche
- (2014) John R. B. Perry et al. NATURE
- Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease
- (2014) Mike A Nalls et al. NATURE GENETICS
- Neuronal vulnerability, pathogenesis, and Parkinson's disease
- (2012) David Sulzer et al. MOVEMENT DISORDERS
- The Local Transcriptome in the Synaptic Neuropil Revealed by Deep Sequencing and High-Resolution Imaging
- (2012) Iván J. Cajigas et al. NEURON
- Systematic Localization of Common Disease-Associated Variation in Regulatory DNA
- (2012) M. T. Maurano et al. SCIENCE
- METAL: fast and efficient meta-analysis of genomewide association scans
- (2010) C. J. Willer et al. BIOINFORMATICS
- Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt
- (2009) Steffen Durinck et al. Nature Protocols
- Second consensus statement on the diagnosis of multiple system atrophy
- (2008) S. Gilman et al. NEUROLOGY
- Loss of cholinergic neurons in the pedunculopontine nucleus in Parkinson's disease is related to disability of the patients
- (2008) Juha O. Rinne et al. PARKINSONISM & RELATED DISORDERS
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