SCUBE3 downregulation modulates hepatocellular carcinoma by inhibiting CCNE1 via TGFβ/PI3K/AKT/GSK3β pathway

Activation of TGF-β1 Pathway by SCUBE3 Regulates TWIST1 Expression and Promotes Breast Cancer Progression

(2020) Xuhui Yang et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Identification of the fatty acid synthase interaction network via iTRAQ-based proteomics indicates the potential molecular mechanisms of liver cancer metastasis

(2020) Juan Huang et al.   Cancer Cell International

Reduction of SCUBE3 by a new marine-derived asterosaponin leads to arrest of glioma cells in G1/S

(2020) Peng-Cheng Qiu et al.   Oncogenesis

SCUBE3 loss-of-function causes a recognizable recessive developmental disorder due to defective bone morphogenetic protein signaling

(2020) Yuh-Charn Lin et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Hepatocellular Carcinoma

(2019) Augusto Villanueva   NEW ENGLAND JOURNAL OF MEDICINE

Molecular and histological correlations in liver cancer

(2019) Julien Calderaro et al.   JOURNAL OF HEPATOLOGY

Molecular therapies and precision medicine for hepatocellular carcinoma

(2018) Josep M. Llovet et al.   Nature Reviews Clinical Oncology

MicroRNA-206 prevents the pathogenesis of hepatocellular carcinoma by modulating expression of met proto-oncogene and cyclin-dependent kinase 6 in mice

(2017) Heng Wu et al.   HEPATOLOGY

Sunitinib Induces NK-κB-dependent NKG2D Ligand Expression in Nasopharyngeal Carcinoma and Hepatoma Cells

(2017) Yu-xian Huang et al.   JOURNAL OF IMMUNOTHERAPY

TGF-β signalling and liver disease

(2016) Isabel Fabregat et al.   FEBS Journal

Non-Smad Signaling Pathways of the TGF-β Family

(2016) Ying E. Zhang   Cold Spring Harbor Perspectives in Biology

Cyclin E1 is a strong prognostic marker for death from lymph node negative breast cancer. A population-based case-control study

(2015) Claudia Lundgren et al.   ACTA ONCOLOGICA

The Expression of HSPD1, SCUBE3, CXCL14 and Its Relations with the Prognosis in Osteosarcoma

(2015) Wenqing Liang et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Genetic Landscape and Biomarkers of Hepatocellular Carcinoma

(2015) Jessica Zucman-Rossi et al.   GASTROENTEROLOGY

HBx-related long non-coding RNA DBH-AS1 promotes cell proliferation and survival by activating MAPK signaling in hepatocellular carcinoma

(2015) Jin-lan Huang et al.   Oncotarget

Akbu-LAAO exhibits potent anti-tumor activity to HepG2 cells partially through produced H2O2 via TGF-β signal pathway

(2015) Chunmei Guo et al.   Scientific Reports

Moving towards personalised therapy in patients with hepatocellular carcinoma: the role of the microenvironment

(2014) Gianluigi Giannelli et al.   GUT

SCUBE3 (Signal Peptide-CUB-EGF Domain-containing Protein 3) Modulates Fibroblast Growth Factor Signaling during Fast Muscle Development

(2014) Cheng-Fen Tu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SMAD4 exerts a tumor-promoting role in hepatocellular carcinoma

(2014) P Y Hernanda et al.   ONCOGENE

SCUBE3 regulation of early lung cancer angiogenesis and metastatic progression

(2013) Cheng-Hung Chou et al.   CLINICAL & EXPERIMENTAL METASTASIS

Scube regulates synovial angiogenesis-related signaling

(2013) Min Yang et al.   MEDICAL HYPOTHESES

Scube3 Is Expressed in Multiple Tissues during Development but Is Dispensable for Embryonic Survival in the Mouse

(2013) Guilherme M. Xavier et al.   PLoS One

Co-Expression of XIAP and Cyclin D1 Complex Correlates with a Poor Prognosis in Patients with Hepatocellular Carcinoma

(2012) Yufang Che et al.   AMERICAN JOURNAL OF PATHOLOGY

Global transgenerational gene expression dynamics in two newly synthesized allohexaploid wheat (Triticum aestivum) lines

(2012) Bao Qi et al.   BMC BIOLOGY

Mir-33 regulates cell proliferation and cell cycle progression

(2012) Daniel Cirera-Salinas et al.   CELL CYCLE

TGFβ signalling in context

(2012) Joan Massagué   NATURE REVIEWS MOLECULAR CELL BIOLOGY

TGF-β in progression of liver disease

(2011) Steven Dooley et al.   CELL AND TISSUE RESEARCH

SCUBE3 is an endogenous TGF-β receptor ligand and regulates the epithelial-mesenchymal transition in lung cancer

(2011) Y-Y Wu et al.   ONCOGENE

Cyclin E amplification/overexpression is a mechanism of trastuzumab resistance in HER2+breast cancer patients

(2011) Maurizio Scaltriti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer gene discovery in hepatocellular carcinoma

(2010) Lars Zender et al.   JOURNAL OF HEPATOLOGY

Mitogen-activated protein kinases in hepatocellular carcinoma development

(2010) Lihua Min et al.   SEMINARS IN CANCER BIOLOGY