Enhancing biosynthesis of 2'‐Fucosyllactose in Escherichia coli  through engineering lactose operon for lactose transport and α ‐1,2‐Fucosyltransferase for solubility

Strain-specific strategies of 2′-fucosyllactose, 3-fucosyllactose, and difucosyllactose assimilation by Bifidobacterium longum subsp. infantis Bi-26 and ATCC 15697

(2020) Bryan E. Zabel et al.   Scientific Reports

High-Titer De Novo Biosynthesis of the Predominant Human Milk Oligosaccharide 2′-Fucosyllactose from Sucrose in Escherichia coli

(2020) Katja Parschat et al.   ACS Synthetic Biology

Production of 3‐Fucosyllactose in Engineered Escherichia coli with α‐1,3‐Fucosyltransferase from Helicobacter pylori

(2019) Sang‐Min Jung et al.   Biotechnology Journal

Enhanced production of 2’‐fucosyllactose from fucose by elimination of rhamnose isomerase and arabinose isomerase in engineered Escherichia coli

(2019) Sang‐Min Jung et al.   BIOTECHNOLOGY AND BIOENGINEERING

Biosynthesis of the human milk oligosaccharide 3‐fucosyllactose in metabolically engineered Escherichia coli via the salvage pathway through increasing GTP synthesis and β‐galactosidase modification

(2019) Yun Hee Choi et al.   BIOTECHNOLOGY AND BIOENGINEERING

Impact of maternal characteristics on human milk oligosaccharide composition over the first 4 months of lactation in a cohort of healthy European mothers

(2019) Tinu Mary Samuel et al.   Scientific Reports

Engineering the Substrate Transport and Cofactor Regeneration Systems for Enhancing 2′-Fucosyllactose Synthesis in Bacillus subtilis

(2019) Jieying Deng et al.   ACS Synthetic Biology

Human Milk Oligosaccharides and Associations With Immune-Mediated Disease and Infection in Childhood: A Systematic Review

(2018) Alice M. Doherty et al.   Frontiers in Pediatrics

Human Milk Oligosaccharides: 2′-Fucosyllactose (2′-FL) and Lacto-N-Neotetraose (LNnT) in Infant Formula

(2018) Yvan Vandenplas et al.   Nutrients

Engineering two species of yeast as cell factories for 2′-fucosyllactose

(2018) Kerry Hollands et al.   METABOLIC ENGINEERING

Metabolic engineering of Escherichia coli for the production of 2′-fucosyllactose and 3-fucosyllactose through modular pathway enhancement

(2017) Di Huang et al.   METABOLIC ENGINEERING

Systematic review of the concentrations of oligosaccharides in human milk

(2017) Stephan Thurl et al.   NUTRITION REVIEWS

Longitudinal change of selected human milk oligosaccharides and association to infants’ growth, an observatory, single center, longitudinal cohort study

(2017) Norbert Sprenger et al.   PLoS One

Solubilization and Iterative Saturation Mutagenesis of α1,3-fucosyltransferase fromHelicobacter pylorito enhance its catalytic efficiency

(2016) Yun Hee Choi et al.   BIOTECHNOLOGY AND BIOENGINEERING

Metabolic engineering of Escherichia coli to produce 2′-fucosyllactose via salvage pathway of guanosine 5′-diphosphate (GDP)-l -fucose

(2016) Young-Wook Chin et al.   BIOTECHNOLOGY AND BIOENGINEERING

Similar to Those Who Are Breastfed, Infants Fed a Formula Containing 2′-Fucosyllactose Have Lower Inflammatory Cytokines in a Randomized Controlled Trial

(2016) Karen C Goehring et al.   JOURNAL OF NUTRITION

The Human Milk Oligosaccharide 2′-Fucosyllactose Quenches Campylobacter jejuni–Induced Inflammation in Human Epithelial Cells HEp-2 and HT-29 and in Mouse Intestinal Mucosa

(2016) Zhuo-Teng Yu et al.   JOURNAL OF NUTRITION

Enhanced production of 2′-fucosyllactose in engineered Escherichia coli BL21star(DE3) by modulation of lactose metabolism and fucosyltransferase

(2015) Young-Wook Chin et al.   JOURNAL OF BIOTECHNOLOGY

Effects of a human milk oligosaccharide, 2′-fucosyllactose, on hippocampal long-term potentiation and learning capabilities in rodents

(2015) Enrique Vázquez et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Breast Milk Oligosaccharides: Structure-Function Relationships in the Neonate

(2014) Jennifer T. Smilowitz et al.   Annual Review of Nutrition

Recent advances in human milk glycobiology

(2014) David S. Newburg et al.   PEDIATRIC RESEARCH

Construction of Escherichia coli strains with chromosomally integrated expression cassettes for the synthesis of 2′-fucosyllactose

(2013) Florian Baumgärtner et al.   Microbial Cell Factories

Bioengineered 2′-fucosyllactose and 3-fucosyllactose inhibit the adhesion of Pseudomonas aeruginosa and enteric pathogens to human intestinal and respiratory cell lines

(2013) Stefan Weichert et al.   NUTRITION RESEARCH

Gene Position More Strongly Influences Cell-Free Protein Expression from Operons than T7 Transcriptional Promoter Strength

(2013) Fabio Chizzolini et al.   ACS Synthetic Biology

Human milk oligosaccharides: Every baby needs a sugar mama

(2012) L. Bode   GLYCOBIOLOGY

Efficient synthesis of 6′-sialyllactose, 6,6′-disialyllactose, and 6′-KDO-lactose by metabolically engineered E. coli expressing a multifunctional sialyltransferase from the Photobacterium sp. JT-ISH-224

(2010) Sophie Drouillard et al.   CARBOHYDRATE RESEARCH

Human milk glycobiome and its impact on the infant gastrointestinal microbiota

(2010) A. M. Zivkovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic engineering of Escherichia coli for the economical production of sialylated oligosaccharides

(2008) N FIERFORT et al.   JOURNAL OF BIOTECHNOLOGY

Rapid and efficient construction of markerless deletions in the Escherichia coli genome

(2008) B. J. Yu et al.   NUCLEIC ACIDS RESEARCH