New bis- and tetrakis-1,2,3-triazole derivatives: Synthesis, DNA cleavage, molecular docking, antimicrobial, antioxidant activity and acid dissociation constants

DNA-cleavage activity of the iron(II) complex with optically active ligands, meta- and para-xylyl-linked N’,N’-dipyridylmethyl-cyclohexane-1,2-diamine

(2021) Koichi Kato et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

In vitro antifungal activities, molecular docking, and DFT studies of 4-amine-3-hydrazino-5-mercapto-1,2,4-triazole derivatives

(2021) Le Qi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Comprehensive research on potent and selective carbonic anhydrase inhibitors: Synthesis, bioactivities and molecular modelling studies of 4-(3-(2-arylidenehydrazine-1-carbonyl)-5-(thiophen-2-yl)-1H-pyrazole-1-yl) benzenesulfonamides

(2021) Cem Yamali et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Discovery of antiproliferative and anti-FAK inhibitory activity of 1,2,4-triazole derivatives containing acetamido carboxylic acid skeleton

(2021) Muhamad Mustafa et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis, Characterization, and Antioxidant and Anticancer Activity of 1,4-Disubstituted 1,2,3-triazoles

(2021) İrfan Şahin et al.   JOURNAL OF MOLECULAR STRUCTURE

Design and synthesis, biological evaluation of bis-(1,2,3- and 1,2,4)-triazole derivatives as potential antimicrobial and antifungal agents

(2021) Sampath Bitla et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Novel triazole-sulfonamide bearing pyrimidine moieties with carbonic anhydrase inhibitory action: Design, synthesis, computational and enzyme inhibition studies

(2021) Shoaib Manzoor et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Novel imidazo[2,1‐ b ]thiazole‐based anticancer agents as potential focal adhesion kinase inhibitors: Synthesis, in silico and in vitro evaluation

(2021) Faika Başoğlu et al.   Chemical Biology & Drug Design

Synthesis, Biological Evaluation, Molecular Docking, and Acid Dissociation Constant of New Bis‐1,2,3‐triazole Compounds

(2021) Yahya Nural et al.   ChemistrySelect

New vinyl-1,2,4-triazole derivatives as antimicrobial agents: Synthesis, biological evaluation and molecular docking studies

(2020) Eugenia Stingaci et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Polysubstituted pyrrolidines linked to 1,2,3-triazoles: Synthesis, crystal structure, DFT studies, acid dissociation constant, drug-likeness, and anti-proliferative activity

(2020) Tuncay Ince et al.   JOURNAL OF MOLECULAR STRUCTURE

Synthesis, Characterization, DNA Binding, Docking, and Anticancer Studies of Novel Bis‐1,2,3‐triazoles Phthalonitrile

(2020) Shaya Yahya Alraqa et al.   ChemistrySelect

Synthesis, biological properties, and acid dissociation constant of novel naphthoquinone–triazole hybrids

(2020) Yahya Nural et al.   BIOORGANIC CHEMISTRY

Nucleophile Screening in Anion-binding Reissert-type Reactions of Quinolines with Chiral TetrakisTriazole Catalysts

(2019) Qui-Nhi Duong et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Discovery of 1,2,3-triazole-based fibroblast growth factor receptor modulators

(2019) Hiroki Sakai et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design, click synthesis, anticancer screening and docking studies of novel benzothiazole-1,2,3-triazoles appended with some bioactive benzofused heterocycles

(2019) Mohamed Reda Aouad et al.   JOURNAL OF MOLECULAR STRUCTURE

1,2,3-Triazole-containing hybrids as leads in medicinal chemistry: A recent overview

(2019) Khurshed Bozorov et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis of new thiazolyl-pyrazolyl-1,2,3-triazole derivatives as potential antimicrobial agents

(2019) Jitendra Nalawade et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, Synthesis, and Biological Activity of New Bis-1,2,3-triazole Derivatives Bearing Thiophene-Chalcone Moiety

(2019) K. Kiran et al.   RUSSIAN JOURNAL OF GENERAL CHEMISTRY

The bioisosteric modification of pyrazinamide derivatives led to potent antitubercular agents: Synthesis via click approach and molecular docking of pyrazine-1,2,3-triazoles

(2019) Rajkumar Reddyrajula et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Facile synthesis of 1,2,3-triazole-fused indolo- and pyrrolo[1,4]diazepines, DNA-binding and evaluation of their anticancer activity

(2019) Jitendra Gour et al.   BIOORGANIC CHEMISTRY

1,2,3-Triazole-containing hybrids as potential anticancer agents: Current developments, action mechanisms and structure-activity relationships

(2019) Zhi Xu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The genome-wide sequence specificity of DNA cleavage by bleomycin analogues in human cells

(2018) Vincent Murray et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis, antimicrobial activity and acid dissociation constants of methyl 5,5-diphenyl-1-(thiazol-2-yl)pyrrolidine-2-carboxylate derivatives

(2018) Yahya Nural et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis, crystal structure, DFT studies, acid dissociation constant, and antimicrobial activity of methyl 2-(4-chlorophenyl)-7a-((4-chlorophenyl)carbamothioyl)-1-oxo-5,5-diphenyl-3-thioxo-hexahydro-1H-pyrrolo[1,2-e]imidazole-6-carboxylate

(2018) Yahya Nural et al.   JOURNAL OF MOLECULAR STRUCTURE

Synthesis, Characterization and Biological Activities of New Symmetric Bis-1,2,3-Triazoles with Click Chemistry

(2018) Fatih Celik et al.   Medicinal Chemistry

Synthesis, antimycobacterial activity, and acid dissociation constants of polyfunctionalized 3-[2-(pyrrolidin-1-yl)thiazole-5-carbonyl]-2H-chromen-2-one derivatives

(2018) Yahya Nural   MONATSHEFTE FUR CHEMIE

Discrete Cu(i) complexes for azide–alkyne annulations of small molecules inside mammalian cells

(2018) Joan Miguel-Ávila et al.   Chemical Science

Novel 1,4-naphthoquinone N-aroylthioureas: Syntheses, crystal structure, anion recognition properties, DFT studies and determination of acid dissociation constants

(2018) Müge Gemili et al.   JOURNAL OF MOLECULAR LIQUIDS

Novel tacrine-coumarin hybrids linked to 1,2,3-triazole as anti-Alzheimer’s compounds: In vitro and in vivo biological evaluation and docking study

(2018) Zahra Najafi et al.   BIOORGANIC CHEMISTRY

Pt(II) and Ni(II) complexes of octahydropyrrolo[3,4-c]pyrrole N -benzoylthiourea derivatives: Synthesis, characterization, physical parameters and biological activity

(2017) Muge Gemili et al.   INORGANICA CHIMICA ACTA

Indole-2-carboxylic acid derived mono and bis 1,4-disubstituted 1,2,3-triazoles: Synthesis, characterization and evaluation of anticancer, antibacterial, and DNA-cleavage activities

(2016) Sirassu Narsimha et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and physiochemical properties of novel gemini surfactants with phenyl-1,4-bis(carbamoylmethyl) spacer

(2015) Liyan Wang et al.   RSC Advances

[Fe2L3]4+ Cylinders Derived from Bis(bidentate) 2-Pyridyl-1,2,3-triazole “Click” Ligands: Synthesis, Structures and Exploration of Biological Activity

(2013) Sreedhar Vellas et al.   MOLECULES

Experimental and Theoretical Study on the Electrochemical Behavior of Zofenopril and its Voltammetric Determination

(2012) Ibrahim Hudai Tasdemir et al.   Current Pharmaceutical Analysis

Synthesis and in vitro evaluation of potential anticancer activity of mono- and bis-1,2,3-triazole derivatives of bis-alkynes

(2012) Hichem Elamari et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The copper(I)-catalyzed alkyne-azide cycloaddition (CuAAC) “click” reaction and its applications. An overview

(2011) Liyuan Liang et al.   COORDINATION CHEMISTRY REVIEWS

Click chemistry with DNA

(2010) Afaf H. El-Sagheer et al.   CHEMICAL SOCIETY REVIEWS

Exploring QSAR on 4-Cyclohexylmethoxypyrimidines as Antitumor Agents for Their Inhibitory Activity of CDK2

(2010) A. Ece et al.   Letters in Drug Design & Discovery

The acid–base profile of a contemporary set of drugs: implications for drug discovery

(2009) D.T. Manallack   SAR AND QSAR IN ENVIRONMENTAL RESEARCH