Synthesis, Biological Evaluation, Molecular Docking, and Acid Dissociation Constant of New Bis‐1,2,3‐triazole Compounds

CuAAC Mediated Synthesis of 2‐HBT Linked Bioactive 1,2,3‐Triazole Hybrids: Investigations through Fluorescence, DNA Binding, Molecular Docking, ADME Predictions and DFT Study

(2021) Nidhi Nehra et al.   ChemistrySelect

Novel 1‐Triazolylpyranopyrazoles as Highly Potent Anticancer Agents Obtained via MW‐Assisted Synthesis

(2021) Rakesh Kumar et al.   ChemistrySelect

DNA-cleavage activity of the iron(II) complex with optically active ligands, meta- and para-xylyl-linked N’,N’-dipyridylmethyl-cyclohexane-1,2-diamine

(2021) Koichi Kato et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design, Synthesis, and Biological Evaluation of Membrane-Active Bakuchiol Derivatives as Effective Broad-Spectrum Antibacterial Agents

(2021) Hongxia Li et al.   JOURNAL OF MEDICINAL CHEMISTRY

Design and synthesis, biological evaluation of bis-(1,2,3- and 1,2,4)-triazole derivatives as potential antimicrobial and antifungal agents

(2021) Sampath Bitla et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design, synthesis, characterization, in vitro and in silico evaluation of novel imidazo[2,1-b][1,3,4]thiadiazoles as highly potent acetylcholinesterase and non-classical carbonic anhydrase inhibitors

(2021) Sercan Askin et al.   BIOORGANIC CHEMISTRY

Novel imidazo[2,1‐ b ]thiazole‐based anticancer agents as potential focal adhesion kinase inhibitors: Synthesis, in silico and in vitro evaluation

(2021) Faika Başoğlu et al.   Chemical Biology & Drug Design

Synthesis of a 1,2,3-bistriazole derivative of embelin and evaluation of its effect on high-fat diet fed-streptozotocin-induced type 2 diabetes in rats and molecular docking studies

(2020) Antony Stalin et al.   BIOORGANIC CHEMISTRY

Click‐Derived Uracil‐Appended Organosilatranyl Scaffolds: Synthesis, Antibacterial Characteristics, Pb2+ Binding and Fabrication of Hybrid Silica Nanoparticles

(2020) Gurjaspreet Singh et al.   ChemistrySelect

Bioactive indanes: insight into the bioactivity of indane dimers related to the lead anti‐inflammatory molecule PH46A

(2020) Kit Chan et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Synthesis and antimicrobial evaluation of new thiazolyl-1,2,3-triazolyl-alcohol derivatives

(2020) Shivaji Jagadale et al.   MEDICINAL CHEMISTRY RESEARCH

Regioselective synthesis, antibacterial, and antioxidant activities of ester-linked 1,4-disubstituted 1,2,3-triazoles

(2020) C. P. Kaushik et al.   MONATSHEFTE FUR CHEMIE

Synthesis and Biological Evaluation of New 1,2,3‐Triazolyl‐Pyrazolyl‐Quinoline Derivatives as Potential Antimicrobial Agents

(2020) Prashant P. Thakare et al.   ChemistrySelect

Synthesis, Antimicrobial Activity, Molecular Docking and DFT Study: Aryl‐Carbamic Acid 1‐Benzyl‐1 H ‐[1,2,3]Triazol‐4‐ylmethyl Esters

(2020) Naveen et al.   ChemistrySelect

Synthesis and Antitubercular Activity of 4,5‐Disubstituted N 1 ‐(5′‐deoxythymidin‐5′‐yl)‐1,2,3‐triazoles

(2020) Rajesh Kumar et al.   ChemistrySelect

Polysubstituted pyrrolidines linked to 1,2,3-triazoles: Synthesis, crystal structure, DFT studies, acid dissociation constant, drug-likeness, and anti-proliferative activity

(2020) Tuncay Ince et al.   JOURNAL OF MOLECULAR STRUCTURE

Organocatalysis in the Synthesis of 1,2,3‐Triazoyl‐zidovudine Derivatives: Synthesis and Preliminary Antioxidant Activity

(2020) Carolina B. Gomes et al.   ChemistrySelect

Synthesis, biological properties, and acid dissociation constant of novel naphthoquinone–triazole hybrids

(2020) Yahya Nural et al.   BIOORGANIC CHEMISTRY

Recent applications of click chemistry in drug discovery

(2019) Xiangyi Jiang et al.   Expert Opinion on Drug Discovery

Design, Synthesis and Biological Evaluation of Substituted (1-(4-chlorobenzyl)-1H -indol-3-yl) 1H -(1,2,3-triazol-4-yl)methanones as Antifungal Agents

(2019) Mohd Adil Shareef et al.   ChemistrySelect

One pot multicomponent synthesis of Novel Bis‐ N ‐(1,2,3‐ triazolylacetyl) as Potent Antioxidant and Antibacterial Agents

(2019) Jafar. Parvizi et al.   ChemistrySelect

Synthesis and Biological evaluation of morpholines linked coumarin‐triazole hybrids as anticancer agents

(2019) Nerella Sridhar Goud et al.   Chemical Biology & Drug Design

Design, click synthesis, anticancer screening and docking studies of novel benzothiazole-1,2,3-triazoles appended with some bioactive benzofused heterocycles

(2019) Mohamed Reda Aouad et al.   JOURNAL OF MOLECULAR STRUCTURE

Method of UV-Metric and pH-Metric Determination of Dissociation Constants of Ionizable Drugs: Valsartan

(2019) Milan Meloun et al.   JOURNAL OF SOLUTION CHEMISTRY

New amide linked dimeric 1,2,3-triazoles bearing aryloxy scaffolds as a potent antiproliferative agents and EGFR tyrosine kinase phosphorylation inhibitors

(2019) Tejshri R. Deshmukh et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of new thiazolyl-pyrazolyl-1,2,3-triazole derivatives as potential antimicrobial agents

(2019) Jitendra Nalawade et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design and microwave-assisted synthesis of dimers of 1,5-benzodiazepine-1,2,3-triazole hybrids bearing alkyl/aryl spacers and their biological assessment

(2019) Zouhour Jaafar et al.   JOURNAL OF MOLECULAR STRUCTURE

Synthesis, Anticancer Evaluation and DNA‐Binding Spectroscopic Insights of Quinoline‐Based 1,3,4‐Oxadiazole‐1,2,3‐triazole Conjugates

(2019) Farheen Shamsi et al.   ChemistrySelect

“Quinoline Consists of 1 H ‐1,2,3‐Triazole Hybrids: Design, Synthesis and Anticancer Evaluation”

(2019) Sivarami Reddy Gangireddy Venkata et al.   ChemistrySelect

Synthesis, antimicrobial activity and acid dissociation constants of methyl 5,5-diphenyl-1-(thiazol-2-yl)pyrrolidine-2-carboxylate derivatives

(2018) Yahya Nural et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis, crystal structure, DFT studies, acid dissociation constant, and antimicrobial activity of methyl 2-(4-chlorophenyl)-7a-((4-chlorophenyl)carbamothioyl)-1-oxo-5,5-diphenyl-3-thioxo-hexahydro-1H-pyrrolo[1,2-e]imidazole-6-carboxylate

(2018) Yahya Nural et al.   JOURNAL OF MOLECULAR STRUCTURE

Synthesis, antimycobacterial activity, and acid dissociation constants of polyfunctionalized 3-[2-(pyrrolidin-1-yl)thiazole-5-carbonyl]-2H-chromen-2-one derivatives

(2018) Yahya Nural   MONATSHEFTE FUR CHEMIE

Design and synthesis of fluorescent symmetric bis-triazolylated-1,4-dihydropyridines as potent antibreast cancer agents

(2018) Rakesh Kumar et al.   SYNTHETIC COMMUNICATIONS

Click Chemistry Inspired Design, Synthesis and Molecular Docking Studies of Coumarin, Quinolinone Linked 1,2,3-Triazoles as Promising Anti-Microbial Agents

(2018) Hemantkumar M. Savanur et al.   ChemistrySelect

Synthesis, characterization, and evaluation of antifungal and antioxidant properties of cationic chitosan derivative via azide-alkyne click reaction

(2018) Wenqiang Tan et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Synthesis and Evaluation of Antifungal and Antitrypanosomastid Activities of Symmetrical 1,4-Disubstituted-1,2,3-Bistriazoles Obtained by CuAAC Conditions

(2018) Mauricio M. Victor et al.   Medicinal Chemistry

Design, synthesis, structural characterization and in vitro evaluation of new 1,4-disubstituted-1,2,3-triazole derivatives against glioblastoma cells

(2018) Veronica D. da Silva et al.   BIOORGANIC CHEMISTRY

Pt(II) and Ni(II) complexes of octahydropyrrolo[3,4-c]pyrrole N -benzoylthiourea derivatives: Synthesis, characterization, physical parameters and biological activity

(2017) Muge Gemili et al.   INORGANICA CHIMICA ACTA

Symmetric molecules with 1,4-triazole moieties as potent inhibitors of tumour-associated lactate dehydrogenase-A

(2017) Abdul-Malek S. Altamimi et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

A rapid synthesis of 2-substituted 1,2,3- triazole-1-oxide derivative starting from 4-(methyl)isonitrosoacetophenone and its Ni(II) complex: Characterization, DNA binding and cleavage properties

(2017) Ramazan Gup et al.   JOURNAL OF MOLECULAR STRUCTURE

Ring Functionalization and Molecular Hybridization of Quinolinyl Pyrazole: Design, Synthesis and Antimycobacterial Activity

(2017) Venkatesham Rachakonda et al.   ChemistrySelect

HDAC and NF-κB mediated cytotoxicity induced by novel N-Chloro β-lactams and benzisoxazole derivatives

(2016) C.B. Rajashekar Reddy et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Design, synthesis and biological evaluation of ciprofloxacin tethered bis-1,2,3-triazole conjugates as potent antibacterial agents

(2016) Rama Kant et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of Novel Symmetrical 1,4-Disubstituted 1,2,3-Bistriazole Derivatives via ‘Click Chemistry’ and Their Biological Evaluation

(2016) Esra Düğdü et al.   MOLECULES

The Synthesis, Characterization, Acid Dissociation, and Theoretical Calculation of Several Novel Benzothiazole Schiff Base Derivatives

(2015) Kamuran Görgün et al.   JOURNAL OF CHEMICAL AND ENGINEERING DATA

Synthesis, Characterization, and Antimicrobial Potential of Some 1,4-Disubstituted 1,2,3-Bistriazoles

(2015) C. P. Kaushik et al.   SYNTHETIC COMMUNICATIONS

Phenanthroline-2,9-bistriazoles as selective G-quadruplex ligands

(2013) Mads Corvinius Nielsen et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological evaluation of amino acid-linked 1,2,3-bistriazole conjugates as potential antimicrobial agents

(2013) C. P. Kaushik et al.   MEDICINAL CHEMISTRY RESEARCH

Iron and Reactive Oxygen Species: Friends or Foes of Cancer Cells?

(2012) Laura M. Bystrom et al.   ANTIOXIDANTS & REDOX SIGNALING

Solvent effect on copper-catalyzed azide–alkyne cycloaddition (CuAAC): Synthesis of novel triazolyl substituted quinolines as potential anticancer agents

(2012) Amarender Reddy Ellanki et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Experimental and Theoretical Study on the Electrochemical Behavior of Zofenopril and its Voltammetric Determination

(2012) Ibrahim Hudai Tasdemir et al.   Current Pharmaceutical Analysis

The copper(I)-catalyzed alkyne-azide cycloaddition (CuAAC) “click” reaction and its applications. An overview

(2011) Liyuan Liang et al.   COORDINATION CHEMISTRY REVIEWS

Protective effect of two edible mushrooms against oxidative cell damage and their phenolic composition

(2011) Feyza Oke et al.   FOOD CHEMISTRY

Zinc selective chemosensor based on pyridyl-amide fluorescence

(2011) Hong Gyu Lee et al.   TETRAHEDRON

Click chemistry with DNA

(2010) Afaf H. El-Sagheer et al.   CHEMICAL SOCIETY REVIEWS

Exploring QSAR on 4-Cyclohexylmethoxypyrimidines as Antitumor Agents for Their Inhibitory Activity of CDK2

(2010) A. Ece et al.   Letters in Drug Design & Discovery