Enhanced single-cell RNA-seq workflow reveals coronary artery disease cellular cross-talk and candidate drug targets

Inference and analysis of cell-cell communication using CellChat

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Cardio-Immuno-Oncology

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Visualization of cardiovascular development, physiology and disease at the single-cell level: Opportunities and future challenges

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The Stem Cell Pluripotency Genes Klf4 and Oct4 Regulate Complex SMC Phenotypic Changes Critical in Late-Stage Atherosclerotic Lesion Pathogenesis

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The first case of COVID-19 treated with the complement C3 inhibitor AMY-101

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Clonally expanding smooth muscle cells promote atherosclerosis by escaping efferocytosis and activating the complement cascade

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Identification of key genes in ruptured atherosclerotic plaques by weighted gene correlation network analysis

(2020) Bao-Feng Xu et al.   Scientific Reports

microRNA-9 Inhibits Vulnerable Plaque Formation and Vascular Remodeling via Suppression of the SDC2-Dependent FAK/ERK Signaling Pathway in Mice With Atherosclerosis

(2020) Ruihong Zhang et al.   Frontiers in Physiology

The complement system in COVID-19: friend and foe?

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Single-Cell Genomics Reveals a Novel Cell State During Smooth Muscle Cell Phenotypic Switching and Potential Therapeutic Targets for Atherosclerosis in Mouse and Human

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Immunity and Inflammation in Atherosclerosis

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Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage

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The single-cell transcriptional landscape of mammalian organogenesis

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CXCL12 Derived From Endothelial Cells Promotes Atherosclerosis to Drive Coronary Artery Disease

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A comparison of single-cell trajectory inference methods

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Single-cell expression profiling reveals dynamic flux of cardiac stromal, vascular and immune cells in health and injury

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Single-cell lineage tracing by endogenous mutations enriched in transposase accessible mitochondrial DNA

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Smooth Muscle Cell Phenotypic Diversity

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Comprehensive Integration of Single-Cell Data

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Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis

(2019) Robert C. Wirka et al.   NATURE MEDICINE

Vascular smooth muscle cells in atherosclerosis

(2019) Gemma L. Basatemur et al.   Nature Reviews Cardiology

Supervised classification enables rapid annotation of cell atlases

(2019) Hannah A. Pliner et al.   NATURE METHODS

Cardioinformatics: the nexus of bioinformatics and precision cardiology

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Slingshot: cell lineage and pseudotime inference for single-cell transcriptomics

(2018) Kelly Street et al.   BMC GENOMICS

Taming Immune and Inflammatory Responses to Treat Atherosclerosis ∗

(2018) Peter Libby et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

RNA velocity of single cells

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DrugThatGene: integrative analysis to streamline the identification of druggable genes, pathways and protein complexes from CRISPR screens

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Changes in IGFBP-2 levels following a one-year lifestyle modification program are independently related to improvements in plasma apo B and LDL apo B levels

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DGIdb 3.0: a redesign and expansion of the drug–gene interaction database

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Angiogenesis in the atherosclerotic plaque

(2017) Caroline Camaré et al.   Redox Biology

Vascular Smooth Muscle Cells in Atherosclerosis

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The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible

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Gene expression signatures, pathways and networks in carotid atherosclerosis

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An expression atlas of human primary cells: inference of gene function from coexpression networks

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DGIdb: mining the druggable genome

(2013) Malachi Griffith et al.   NATURE METHODS

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

Fibulin-1 and fibrinogen in human atherosclerotic lesions

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