Simvastatin alleviates cardiac fibrosis induced by infarction via up-regulation of TGF-β receptor III expression

Endothelial Dysfunction Exacerbates Renal Interstitial Fibrosis through Enhancing Fibroblast Smad3 Linker Phosphorylation in the Mouse Obstructed Kidney

(2014) Yu Bo Yang Sun et al.   PLoS One

Calcineurin suppresses AMPK-dependent cytoprotective autophagy in cardiomyocytes under oxidative stress

(2014) H He et al.   Cell Death & Disease

The Concise Guide to PHARMACOLOGY 2013/14: Catalytic Receptors

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Concise Guide to PHARMACOLOGY 2013/14: Enzymes

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

HMGCoA reductase inhibition reverses myocardial fibrosis and diastolic dysfunction through AMP-activated protein kinase activation in a mouse model of metabolic syndrome

(2013) Nerea Hermida et al.   CARDIOVASCULAR RESEARCH

The pathogenesis of cardiac fibrosis

(2013) Ping Kong et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands

(2013) Adam J. Pawson et al.   NUCLEIC ACIDS RESEARCH

Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility

(2013) Z. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arsenic trioxide induces cardiac fibroblast apoptosis in vitro and in vivo by up-regulating TGF-β1 expression

(2013) Cui Li et al.   TOXICOLOGY LETTERS

Atorvastatin overcomes gefitinib resistance in KRAS mutant human non-small cell lung carcinoma cells

(2013) J Chen et al.   Cell Death & Disease

HMG-CoA reductase inhibitors induce apoptosis of lymphoma cells by promoting ROS generation and regulating Akt, Erk and p38 signals via suppression of mevalonate pathway

(2013) X-F Qi et al.   Cell Death & Disease

Pravastatin normalizes ET-1-induced contraction in the aorta of type 2 diabetic OLETF rats by suppressing the KSR1/ERK complex

(2012) Shingo Nemoto et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

MicroRNA-101 Inhibited Postinfarct Cardiac Fibrosis and Improved Left Ventricular Compliance via the FBJ Osteosarcoma Oncogene/Transforming Growth Factor-β1 Pathway

(2012) Zhenwei Pan et al.   CIRCULATION

Soluble Glycoprotein 130 Predicts Fatal Outcomes in Chronic Heart Failure

(2012) Erik Tandberg Askevold et al.   Circulation-Heart Failure

A novel reciprocal loop between microRNA-21 and TGFβRIII is involved in cardiac fibrosis

(2012) Haihai Liang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Protection against Ischemia-Induced Oxidative Stress Conferred by Vagal Stimulation in the Rat Heart: Involvement of the AMPK-PKC Pathway

(2012) Shan-Shan Kong et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Effects of dexamethasone on the TGF-β1-induced epithelial-to-mesenchymal transition in human peritoneal mesothelial cells

(2012) Yang-Hee Jang et al.   LABORATORY INVESTIGATION

Endocardial cell epithelial-mesenchymal transformation requires Type III TGFβ receptor interaction with GIPC

(2011) Todd A. Townsend et al.   CELLULAR SIGNALLING

The Efficacy and Safety of the 3-Hydroxy-3-methylglutaryl-CoA Reductase Inhibitors in Chronic Kidney Disease, Dialysis, and Transplant Patients

(2011) A. Olyaei et al.   Clinical Journal of the American Society of Nephrology

The cytoplasmic domain of TGFβR3 through its interaction with the scaffolding protein, GIPC, directs epicardial cell behavior

(2011) Nora S. Sánchez et al.   DEVELOPMENTAL BIOLOGY

Endothelin 1 contributes to the effect of transforming growth factor β1 on wound repair and skin fibrosis

(2010) David Lagares et al.   ARTHRITIS AND RHEUMATISM

Guidelines for reporting experiments involving animals: the ARRIVE guidelines

(2010) JC McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Animal research: Reporting in vivo experiments: The ARRIVE guidelines

(2010) Carol Kilkenny et al.   BRITISH JOURNAL OF PHARMACOLOGY

Roles for the type III TGF-β receptor in human cancer

(2010) Catherine E. Gatza et al.   CELLULAR SIGNALLING

Mitogen-Activated Protein Kinase Inhibitors Improve Heart Function and Prevent Fibrosis in Cardiomyopathy Caused by Mutation in Lamin A/C Gene

(2010) Wei Wu et al.   CIRCULATION

Mechanism of the inhibitory effect of atorvastatin on endoglin expression induced by transforming growth factor-β1 in cultured cardiac fibroblasts

(2010) Kou-Gi Shyu et al.   EUROPEAN JOURNAL OF HEART FAILURE

TGFBR3, a potential negative regulator of TGF-β signaling, protects cardiac fibroblasts from hypoxia-induced apoptosis

(2010) WenFeng Chu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury

(2010) Li Yang et al.   NATURE MEDICINE

Pivotal role of connective tissue growth factor in lung fibrosis: MAPK-dependent transcriptional activation of type I collagen

(2009) Markella Ponticos et al.   ARTHRITIS AND RHEUMATISM

The type III TGF-β receptor suppresses breast cancer progression through GIPC-mediated inhibition of TGF-β signaling

(2009) Jason D. Lee et al.   CARCINOGENESIS

Effects of Statin Therapy According to Plasma High-Sensitivity C-Reactive Protein Concentration in the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA)

(2009) John J.V. McMurray et al.   CIRCULATION

Plasma Concentration of Amino-Terminal Pro-Brain Natriuretic Peptide in Chronic Heart Failure: Prediction of Cardiovascular Events and Interaction With the Effects of Rosuvastatin

(2009) John G.F. Cleland et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Statin-Induced Inhibition of MCF-7 Breast Cancer Cell Proliferation is Related to Cell Cycle Arrest and Apoptotic and Necrotic Cell Death Mediated by an Enhanced Oxidative Stress

(2008) Claudia A. Sánchez et al.   CANCER INVESTIGATION

A synthetic peptide from transforming growth factor- 1 type III receptor prevents myocardial fibrosis in spontaneously hypertensive rats

(2008) N. Hermida et al.   CARDIOVASCULAR RESEARCH

Simvastatin antagonizes tumor necrosis factor-α inhibition of bone morphogenetic proteins-2-induced osteoblast differentiation by regulating Smad signaling and Ras/Rho-mitogen-activated protein kinase pathway

(2008) Misuzu Yamashita et al.   JOURNAL OF ENDOCRINOLOGY

Wide-spread myocardial remodeling after acute myocardial infarction in rat. Features for heart failure progression

(2008) Tadeusz F. Krzemiński et al.   VASCULAR PHARMACOLOGY