HMG-CoA reductase inhibitors induce apoptosis of lymphoma cells by promoting ROS generation and regulating Akt, Erk and p38 signals via suppression of mevalonate pathway

Immunological aspects in chronic lymphocytic leukemia (CLL) development

(2012) Ricardo García-Muñoz et al.   ANNALS OF HEMATOLOGY

Effects of statins and farnesyl transferase inhibitors on ERK phosphorylation, apoptosis and cell viability in non-small lung cancer cells

(2012) G. Pelaia et al.   CELL PROLIFERATION

Atorvastatin delays progression of pancreatic lesions to carcinoma by regulating PI3/AKT signaling in p48Cre/+ LSL-KrasG12D/+ mice

(2012) Altaf Mohammed et al.   INTERNATIONAL JOURNAL OF CANCER

Involvement of Chk1–Cdc25A-cyclin A/CDk2 pathway in simvastatin induced S-phase cell cycle arrest and apoptosis in multiple myeloma cells

(2011) Yong-Sheng Tu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Understanding and Managing Ultra High-Risk Chronic Lymphocytic Leukemia

(2011) S. Stilgenbauer et al.   Hematology-American Society of Hematology Education Program

The Bcl-2 Family as a Rational Target for the Treatment of B-Cell Chronic Lymphocytic Leukaemia

(2010) N. Capitani et al.   CURRENT MEDICINAL CHEMISTRY

Involvement of oxidative stress in simvastatin-induced apoptosis of murine CT26 colon carcinoma cells

(2010) Xu-Feng Qi et al.   TOXICOLOGY LETTERS

Fluvastatin inhibits expression of the chemokine MDC/CCL22 induced by interferon-γ in HaCaT cells, a human keratinocyte cell line

(2009) Xu-Feng Qi et al.   BRITISH JOURNAL OF PHARMACOLOGY

Fibroblast growth factor 8 increases breast cancer cell growth by promoting cell cycle progression and by protecting against cell death

(2009) Emeli M. Nilsson et al.   EXPERIMENTAL CELL RESEARCH

The HMG-CoA inhibitor, simvastatin, triggersin vitroanti-tumour effect and decreases IgM secretion in Waldenstrom macroglobulinaemia

(2008) Anne-Sophie Moreau et al.   BRITISH JOURNAL OF HAEMATOLOGY

Akt Determines Replicative Senescence and Oxidative or Oncogenic Premature Senescence and Sensitizes Cells to Oxidative Apoptosis

(2008) Veronique Nogueira et al.   CANCER CELL

Statin-Induced Inhibition of MCF-7 Breast Cancer Cell Proliferation is Related to Cell Cycle Arrest and Apoptotic and Necrotic Cell Death Mediated by an Enhanced Oxidative Stress

(2008) Claudia A. Sánchez et al.   CANCER INVESTIGATION

New insights into mechanisms of statin-associated myotoxicity

(2008) P SIRVENT et al.   CURRENT OPINION IN PHARMACOLOGY

Combination regimen with statins and NSAIDs: A promising strategy for cancer chemoprevention

(2008) Hang Xiao et al.   INTERNATIONAL JOURNAL OF CANCER

Atorvastatin Increases Myocardial Indices of Oxidative Stress in a Porcine Model of Hypercholesterolemia and Chronic Ischemia

(2008) Neel R. Sodha et al.   JOURNAL OF CARDIAC SURGERY

Lovastatin induces apoptosis of k-ras-transformed thyroid cells via inhibition of ras farnesylation and by modulating redox state

(2008) Chiara Laezza et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Lovastatin enhances gefitinib activity in glioblastoma cells irrespective of EGFRvIII and PTEN status

(2008) Catia Cemeus et al.   JOURNAL OF NEURO-ONCOLOGY

Activation of Nuclear Factor- B Pathway by Simvastatin and RhoA Silencing Increases Doxorubicin Cytotoxicity in Human Colon Cancer HT29 Cells

(2008) C. Riganti et al.   MOLECULAR PHARMACOLOGY

Cytogenetic status and oxidative DNA-damage induced by atorvastatin in human peripheral blood lymphocytes: Standard and Fpg-modified comet assay

(2008) Goran Gajski et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The lack of non-steroid isoprenoids causes oxidative stress in patients with mevalonic aciduria

(2007) Peter Celec et al.   MEDICAL HYPOTHESES