Evaluation of drug-induced QT interval prolongation in animal and human studies: a literature review of concordance

The Concordance between Nonclinical and Phase I Clinical Cardiovascular Assessment from a Cross-Company Data Sharing Initiative

(2014) Lorna Ewart et al.   TOXICOLOGICAL SCIENCES

The Concise Guide to PHARMACOLOGY 2013/14: Ion Channels

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

The impact of drug-related QT prolongation on FDA regulatory decisions

(2013) Eunjung Park et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands

(2013) Adam J. Pawson et al.   NUCLEIC ACIDS RESEARCH

A public–private consortium advances cardiac safety evaluation: Achievements of the HESI Cardiac Safety Technical Committee

(2013) Jennifer B. Pierson et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Evaluation of QTc prolongation in animal and human studies: A qualitative assessment of nonclinical and clinical concordance based on the literature

(2012) Hugo M. Vargas et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

An introduction to QT interval prolongation and non-clinical approaches to assessing and reducing risk

(2010) CE Pollard et al.   BRITISH JOURNAL OF PHARMACOLOGY

An evaluation of hERG current assay performance: Translating preclinical safety studies to clinical QT prolongation

(2010) Gary Gintant   PHARMACOLOGY & THERAPEUTICS

The thorough QT/QTc study 4 years after the implementation of the ICH E14 guidance

(2009) B Darpo   BRITISH JOURNAL OF PHARMACOLOGY

Cheminformatics Analysis of Assertions Mined from Literature That Describe Drug-Induced Liver Injury in Different Species

(2009) Denis Fourches et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Famotidine neither affects action potential parameters nor inhibits human ether-a-go-go-related gene (hERG) K+ current

(2009) Yuji Nakamura et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

A framework to assess the translation of safety pharmacology data to humans

(2009) Jean-Pierre Valentin et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

A HESI consortium approach to assess the human predictive value of non-clinical repolarization assays

(2009) Elena S. Trepakova et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Principles of Safety Pharmacology

(2008) M K Pugsley et al.   BRITISH JOURNAL OF PHARMACOLOGY

Scientific review and recommendations on preclinical cardiovascular safety evaluation of biologics

(2008) Hugo M. Vargas et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS