标题
Molecular insights into the premature aging disease progeria
作者
关键词
Lamins, Premature aging, Progeria, Nucleoplasmic lamins, Chromatin, Signaling, Adult stem cells, Senescence
出版物
HISTOCHEMISTRY AND CELL BIOLOGY
Volume 145, Issue 4, Pages 401-417
出版商
Springer Nature
发表日期
2016-02-04
DOI
10.1007/s00418-016-1411-1
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Accelerated aging syndromes, are they relevant to normal human aging?
- (2016) Oliver Dreesen et al. Aging-US
- NF-κB in premature aging
- (2016) Fernando G. Osorio et al. Aging-US
- Lamins: Nuclear Intermediate Filament Proteins with Fundamental Functions in Nuclear Mechanics and Genome Regulation
- (2015) Yosef Gruenbaum et al. Annual Review of Biochemistry
- Nuclear membrane diversity: underlying tissue-specific pathologies in disease?
- (2015) Howard J Worman et al. CURRENT OPINION IN CELL BIOLOGY
- DNA repair defects and genome instability in Hutchinson–Gilford Progeria Syndrome
- (2015) Susana Gonzalo et al. CURRENT OPINION IN CELL BIOLOGY
- Transgene silencing of the Hutchinson-Gilford progeria syndrome mutation results in a reversible bone phenotype, whereas resveratrol treatment does not show overall beneficial effects
- (2015) Charlotte Strandgren et al. FASEB JOURNAL
- Proliferation of progeria cells is enhanced by lamina-associated polypeptide 2α (LAP2α) through expression of extracellular matrix proteins
- (2015) Sandra Vidak et al. GENES & DEVELOPMENT
- Lamins at the crossroads of mechanosignaling
- (2015) Selma Osmanagic-Myers et al. GENES & DEVELOPMENT
- Prepatterning of differentiation-driven nuclear lamin A/C-associated chromatin domains by GlcNAcylated histone H2B
- (2015) Torunn Rønningen et al. GENOME RESEARCH
- Progeria accelerates adult stem cell aging
- (2015) R. Brunauer et al. SCIENCE
- Loss of lamin A function increases chromatin dynamics in the nuclear interior
- (2015) I. Bronshtein et al. Nature Communications
- Distinct features of lamin A-interacting chromatin domains mapped by ChIP-sequencing from sonicated or micrococcal nuclease-digested chromatin
- (2015) Eivind G Lund et al. Nucleus
- Distinct features of lamin A-interacting chromatin domains mapped by ChIP-sequencing from sonicated or micrococcal nuclease-digested chromatin
- (2015) Eivind G Lund et al. Nucleus
- Sulforaphane enhances progerin clearance in Hutchinson-Gilford progeria fibroblasts
- (2014) Diana Gabriel et al. AGING CELL
- Extracellular matrix: A dynamic microenvironment for stem cell niche
- (2014) Francesca Gattazzo et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Progeria: A Paradigm for Translational Medicine
- (2014) Leslie B. Gordon et al. CELL
- Matrix Elasticity Regulates Lamin-A,C Phosphorylation and Turnover with Feedback to Actomyosin
- (2014) Amnon Buxboim et al. CURRENT BIOLOGY
- Mechanisms and dynamics of nuclear lamina–genome interactions
- (2014) Mario Amendola et al. CURRENT OPINION IN CELL BIOLOGY
- Genetics of aging, progeria and lamin disorders
- (2014) Shrestha Ghosh et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Expression of progerin in aging mouse brains reveals structural nuclear abnormalities without detectible significant alterations in gene expression, hippocampal stem cells or behavior
- (2014) Jean-Ha Baek et al. HUMAN MOLECULAR GENETICS
- Dysregulated interactions between lamin A and SUN1 induce abnormalities in the nuclear envelope and endoplasmic reticulum in progeric laminopathies
- (2014) Z.-J. Chen et al. JOURNAL OF CELL SCIENCE
- Mechanotransduction and extracellular matrix homeostasis
- (2014) Jay D. Humphrey et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Shear stress-induced mechanotransduction protein deregulation and vasculopathy in a mouse model of progeria
- (2014) Minjung Song et al. Stem Cell Research & Therapy
- Identification of differential protein interactors of lamin A and progerin
- (2014) Nard Kubben et al. Nucleus
- Mapping of protein- and chromatin-interactions at the nuclear lamina
- (2014) Nard Kubben et al. Nucleus
- Hutchinson-Gilford progeria syndrome through the lens of transcription
- (2013) Miron Prokocimer et al. AGING CELL
- LMNA-associated cardiocutaneous progeria: An inherited autosomal dominant premature aging syndrome with late onset
- (2013) Megan S. Kane et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- The Hallmarks of Aging
- (2013) Carlos López-Otín et al. CELL
- Single-Cell Dynamics of Genome-Nuclear Lamina Interactions
- (2013) Jop Kind et al. CELL
- LBR and Lamin A/C Sequentially Tether Peripheral Heterochromatin and Inversely Regulate Differentiation
- (2013) Irina Solovei et al. CELL
- Human iPSC-Based Modeling of Late-Onset Disease via Progerin-Induced Aging
- (2013) Justine D. Miller et al. Cell Stem Cell
- Lamin A/C-promoter interactions specify chromatin state-dependent transcription outcomes
- (2013) E. Lund et al. GENOME RESEARCH
- High Mobility Group Protein N5 (HMGN5) and Lamina-associated Polypeptide 2α (LAP2α) Interact and Reciprocally Affect Their Genome-wide Chromatin Organization
- (2013) Shaofei Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Notch signaling at a glance
- (2013) K. Hori et al. JOURNAL OF CELL SCIENCE
- The role of mitochondria in aging
- (2013) Ana Bratic et al. JOURNAL OF CLINICAL INVESTIGATION
- mTOR is a key modulator of ageing and age-related disease
- (2013) Simon C. Johnson et al. NATURE
- Lamina-associated polypeptide (LAP)2α and nucleoplasmic lamins in adult stem cell regulation and disease
- (2013) Kevin Gesson et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Depleting the methyltransferase Suv39h1 improves DNA repair and extends lifespan in a progeria mouse model
- (2013) Baohua Liu et al. Nature Communications
- Lamin A/C is Expressed in Pluripotent Mouse Embryonic Stem Cells
- (2013) Melanie A. Eckersley-Maslin et al. Nucleus
- Label-free mass spectrometry exploits dozens of detected peptides to quantify lamins in wildtype and knockdown cells
- (2013) Joe Swift et al. Nucleus
- An inheritedLMNAgene mutation in atypical Progeria syndrome
- (2012) Yassamine Doubaj et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Resveratrol Rescues SIRT1-Dependent Adult Stem Cell Decline and Alleviates Progeroid Features in Laminopathy-Based Progeria
- (2012) Baohua Liu et al. Cell Metabolism
- Mapping of lamin A- and progerin-interacting genome regions
- (2012) Nard Kubben et al. CHROMOSOMA
- Ageing as a Risk Factor for Disease
- (2012) Teresa Niccoli et al. CURRENT BIOLOGY
- Correlated alterations in genome organization, histone methylation, and DNA-lamin A/C interactions in Hutchinson-Gilford progeria syndrome
- (2012) R. P. McCord et al. GENOME RESEARCH
- Constitutive nuclear lamina-genome interactions are highly conserved and associated with A/T-rich sequence
- (2012) W. Meuleman et al. GENOME RESEARCH
- Expression of the Hutchinson-Gilford Progeria Mutation during Osteoblast Development Results in Loss of Osteocytes, Irregular Mineralization, and Poor Biomechanical Properties
- (2012) Eva Schmidt et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Lamins at a glance
- (2012) C. Y. Ho et al. JOURNAL OF CELL SCIENCE
- NF-κB inhibition delays DNA damage–induced senescence and aging in mice
- (2012) Jeremy S. Tilstra et al. JOURNAL OF CLINICAL INVESTIGATION
- Clinical trial of a farnesyltransferase inhibitor in children with Hutchinson-Gilford progeria syndrome
- (2012) L. B. Gordon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Muscle-derived stem/progenitor cell dysfunction limits healthspan and lifespan in a murine progeria model
- (2012) Mitra Lavasani et al. Nature Communications
- The nuclear envelope proteome differs notably between tissues
- (2012) Nadia Korfali et al. Nucleus
- Naive adult stem cells from patients with Hutchinson-Gilford progeria syndrome express low levels of progerin in vivo
- (2012) V. Wenzel et al. Biology Open
- Stem cell depletion in Hutchinson-Gilford progeria syndrome
- (2011) Ylva Rosengardten et al. AGING CELL
- Néstor-Guillermo progeria syndrome: A novel premature aging condition with early onset and chronic development caused by BANF1 mutations
- (2011) Rubén Cabanillas et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Evolvement of LEM proteins as chromatin tethers at the nuclear periphery
- (2011) Andreas Brachner et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- DNA-damage accumulation and replicative arrest in Hutchinson–Gilford progeria syndrome
- (2011) Phillip R. Musich et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Autophagic degradation of farnesylated prelamin A as a therapeutic approach to lamin-linked progeria
- (2011) V. Cenni et al. EUROPEAN JOURNAL OF HISTOCHEMISTRY
- The accumulation of un-repairable DNA damage in laminopathy progeria fibroblasts is caused by ROS generation and is prevented by treatment with N-acetyl cysteine
- (2011) Shane A. Richards et al. HUMAN MOLECULAR GENETICS
- Progerin and telomere dysfunction collaborate to trigger cellular senescence in normal human fibroblasts
- (2011) Kan Cao et al. JOURNAL OF CLINICAL INVESTIGATION
- Nuclear lamins and laminopathies
- (2011) Howard J. Worman JOURNAL OF PATHOLOGY
- Age-Dependent Loss of MMP-3 in Hutchinson-Gilford Progeria Syndrome
- (2011) I. A. Harten et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Differential expression of extracellular matrix proteins in senescent and young human fibroblasts: A comparative proteomics and microarray study
- (2011) Kyeong Eun Yang et al. MOLECULES AND CELLS
- Splicing-Directed Therapy in a New Mouse Model of Human Accelerated Aging
- (2011) F. G. Osorio et al. Science Translational Medicine
- Lamin A and lamin C form homodimers and coexist in higher complex forms both in the nucleoplasmic fraction and in the lamina of cultured human cells
- (2011) Thorsten Kolb et al. Nucleus
- Cardiovascular Pathology in Hutchinson-Gilford Progeria: Correlation With the Vascular Pathology of Aging
- (2010) Michelle Olive et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- A Human iPSC Model of Hutchinson Gilford Progeria Reveals Vascular Smooth Muscle and Mesenchymal Stem Cell Defects
- (2010) Jinqiu Zhang et al. Cell Stem Cell
- Functional Coupling between the Extracellular Matrix and Nuclear Lamina by Wnt Signaling in Progeria
- (2010) Lidia Hernandez et al. DEVELOPMENTAL CELL
- Signaling Defects and the Nuclear Envelope in Progeria
- (2010) Antoine Muchir et al. DEVELOPMENTAL CELL
- mTOR regulation of autophagy
- (2010) Chang Hwa Jung et al. FEBS LETTERS
- An accumulation of non-farnesylated prelamin A causes cardiomyopathy but not progeria
- (2010) B. S. J. Davies et al. HUMAN MOLECULAR GENETICS
- Absence of progeria-like disease phenotypes in knock-in mice expressing a non-farnesylated version of progerin
- (2010) Shao H. Yang et al. HUMAN MOLECULAR GENETICS
- Role of progerin-induced telomere dysfunction in HGPS premature cellular senescence
- (2010) E. K. Benson et al. JOURNAL OF CELL SCIENCE
- Molecular Maps of the Reorganization of Genome-Nuclear Lamina Interactions during Differentiation
- (2010) Daan Peric-Hupkes et al. MOLECULAR CELL
- Linking functional decline of telomeres, mitochondria and stem cells during ageing
- (2010) Ergün Sahin et al. NATURE
- Can autophagy promote longevity?
- (2010) Frank Madeo et al. NATURE CELL BIOLOGY
- Progeria syndromes and ageing: what is the connection?
- (2010) Christopher R. Burtner et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Defective Lamin A-Rb Signaling in Hutchinson-Gilford Progeria Syndrome and Reversal by Farnesyltransferase Inhibition
- (2010) Jackleen Marji et al. PLoS One
- Nuclear Lamins
- (2010) T. Dechat et al. Cold Spring Harbor Perspectives in Biology
- Lamin-binding Proteins
- (2010) K. L. Wilson et al. Cold Spring Harbor Perspectives in Biology
- Ovarian failure and dilated cardiomyopathy due to a novel lamin mutation
- (2009) Elizabeth McPherson et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Quantification of Hemodynamic Wall Shear Stress in Patients with Bicuspid Aortic Valve Using Phase-Contrast MRI
- (2009) Alex J. Barker et al. ANNALS OF BIOMEDICAL ENGINEERING
- The Posttranslational Processing of Prelamin A and Disease
- (2009) Brandon S.J. Davies et al. Annual Review of Genomics and Human Genetics
- Atypical generalized lipoatrophy and severe insulin resistance due to a heterozygous LMNA p.T10I mutation
- (2009) Patricia B. Mory et al. Arquivos Brasileiros de Endocrinologia e Metabologia
- SIRT6 Links Histone H3 Lysine 9 Deacetylation to NF-κB-Dependent Gene Expression and Organismal Life Span
- (2009) Tiara L.A. Kawahara et al. CELL
- Role of A-type lamins in signaling, transcription, and chromatin organization
- (2009) Vicente Andrés et al. JOURNAL OF CELL BIOLOGY
- Atypical Progeroid Syndrome due to Heterozygous MissenseLMNAMutations
- (2009) Abhimanyu Garg et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Telomere length in Hutchinson-Gilford Progeria Syndrome
- (2009) Michelle L. Decker et al. MECHANISMS OF AGEING AND DEVELOPMENT
- NURD keeps chromatin young
- (2009) Eran Meshorer et al. NATURE CELL BIOLOGY
- Ageing-related chromatin defects through loss of the NURD complex
- (2009) Gianluca Pegoraro et al. NATURE CELL BIOLOGY
- DNA Damage, Aging, and Cancer
- (2009) Jan H.J. Hoeijmakers NEW ENGLAND JOURNAL OF MEDICINE
- Differential requirement of CAAX-mediated posttranslational processing for Rheb localization and signaling
- (2009) A B Hanker et al. ONCOGENE
- Novel LMNA Gene Mutation in a Patient With Atypical Werner's Syndrome
- (2009) Yun Jeong Doh et al. KOREAN JOURNAL OF INTERNAL MEDICINE
- Increased mechanosensitivity and nuclear stiffness in Hutchinson–Gilford progeria cells: effects of farnesyltransferase inhibitors
- (2008) Valerie L. R. M. Verstraeten et al. AGING CELL
- The A- and B-type nuclear lamin networks: microdomains involved in chromatin organization and transcription
- (2008) T. Shimi et al. GENES & DEVELOPMENT
- Nuclear mechanotransduction: Response of the lamina to extracellular stress with implications in aging
- (2008) Julia T. Philip et al. JOURNAL OF BIOMECHANICS
- Fast regulation of AP-1 activity through interaction of lamin A/C, ERK1/2, and c-Fos at the nuclear envelope
- (2008) José María González et al. JOURNAL OF CELL BIOLOGY
- Nuclear envelope defects cause stem cell dysfunction in premature-aging mice
- (2008) Jesús Espada et al. JOURNAL OF CELL BIOLOGY
- Targeted transgenic expression of the mutation causing Hutchinson-Gilford progeria syndrome leads to proliferative and degenerative epidermal disease
- (2008) H. Sagelius et al. JOURNAL OF CELL SCIENCE
- Progerin elicits disease phenotypes of progeria in mice whether or not it is farnesylated
- (2008) Shao H. Yang et al. JOURNAL OF CLINICAL INVESTIGATION
- HGPS and related premature aging disorders: From genomic identification to the first therapeutic approaches
- (2008) Sandrine Pereira et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing
- (2008) Paola Scaffidi et al. NATURE CELL BIOLOGY
- Loss of nucleoplasmic LAP2α–lamin A complexes causes erythroid and epidermal progenitor hyperproliferation
- (2008) Nana Naetar et al. NATURE CELL BIOLOGY
- Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging
- (2008) Ignacio Varela et al. NATURE MEDICINE
- Sirtuins — novel therapeutic targets to treat age-associated diseases
- (2008) Siva Lavu et al. NATURE REVIEWS DRUG DISCOVERY
- Novel LMNA Mutation in Atypical Werner Syndrome Presenting With Ischemic Disease
- (2008) Dimitri Renard et al. STROKE
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