LMNA-associated cardiocutaneous progeria: An inherited autosomal dominant premature aging syndrome with late onset

Singleton-Merten syndrome: An autosomal dominant disorder with variable expression

(2013) Annette Feigenbaum et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

An inheritedLMNAgene mutation in atypical Progeria syndrome

(2012) Yassamine Doubaj et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Accumulation of the Inner Nuclear Envelope Protein Sun1 Is Pathogenic in Progeric and Dystrophic Laminopathies

(2012) Chia-Yen Chen et al.   CELL

A novel homozygous p.Arg527Leu LMNA mutation in two unrelated Egyptian families causes overlapping mandibuloacral dysplasia and progeria syndrome

(2012) Mohammad Al-Haggar et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Correlated alterations in genome organization, histone methylation, and DNA-lamin A/C interactions in Hutchinson-Gilford progeria syndrome

(2012) R. P. McCord et al.   GENOME RESEARCH

Human ZMPSTE24 disease mutations: residual proteolytic activity correlates with disease severity

(2012) Jemima Barrowman et al.   HUMAN MOLECULAR GENETICS

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

Requirements for Efficient Proteolytic Cleavage of Prelamin A by ZMPSTE24

(2012) Jemima Barrowman et al.   PLoS One

Nuclear lamin functions and disease

(2012) Veronika Butin-Israeli et al.   TRENDS IN GENETICS

Coronary artery disease in a Werner syndrome-like form of progeria characterized by low levels of progerin, a splice variant of lamin A

(2011) Fuki M. Hisama et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Clinical and genetic heterogeneity in laminopathies

(2011) Anne T. Bertrand et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Proteomic Profiling of Adipose Tissue from Zmpste24−/−Mice, a Model of Lipodystrophy and Premature Aging, Reveals Major Changes in Mitochondrial Function and Vimentin Processing

(2011) Juan R. Peinado et al.   MOLECULAR & CELLULAR PROTEOMICS

The lamin protein family

(2011) Travis A Dittmer et al.   GENOME BIOLOGY

Post-natal myogenic and adipogenic developmental

(2011) Nard Kubben et al.   Nucleus

Functional Coupling between the Extracellular Matrix and Nuclear Lamina by Wnt Signaling in Progeria

(2010) Lidia Hernandez et al.   DEVELOPMENTAL CELL

Accumulation of distinct prelamin A variants in human diploid fibroblasts differentially affects cell homeostasis

(2010) Jose Candelario et al.   EXPERIMENTAL CELL RESEARCH

Loss of a DNA binding site within the tail of prelamin A contributes to altered heterochromatin anchorage by progerin

(2010) Francine Bruston et al.   FEBS LETTERS

Progeria syndromes and ageing: what is the connection?

(2010) Christopher R. Burtner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Aortic Calcification in a Patient With Hutchinson–Gilford Progeria Syndrome

(2010) Mehrdad Salamat et al.   PEDIATRIC CARDIOLOGY

Homozygous LMNA mutation R527C in atypical Hutchinson-Gilford progeria syndrome: evidence for autosomal recessive inheritance

(2009) Lili Liang et al.   ACTA PAEDIATRICA

Ovarian failure and dilated cardiomyopathy due to a novel lamin mutation

(2009) Elizabeth McPherson et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Progeroid syndrome with scleroderma-like skin changes associated with homozygous R435CLMNAmutation

(2009) Agnieszka Madej-Pilarczyk et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

The Posttranslational Processing of Prelamin A and Disease

(2009) Brandon S.J. Davies et al.   Annual Review of Genomics and Human Genetics

Atypical generalized lipoatrophy and severe insulin resistance due to a heterozygous LMNA p.T10I mutation

(2009) Patricia B. Mory et al.   Arquivos Brasileiros de Endocrinologia e Metabologia

ZMPSTE24, an integral membrane zinc metalloprotease with a connection to progeroid disorders

(2009) Jemima Barrowman et al.   BIOLOGICAL CHEMISTRY

Nuclear lamins: key regulators of nuclear structure and activities

(2009) Miron Prokocimer et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Atypical Progeroid Syndrome due to Heterozygous MissenseLMNAMutations

(2009) Abhimanyu Garg et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Laminopathies and the long strange trip from basic cell biology to therapy

(2009) Howard J. Worman et al.   JOURNAL OF CLINICAL INVESTIGATION

Assessing the efficacy of protein farnesyltransferase inhibitors in mouse models of progeria

(2009) Shao H. Yang et al.   JOURNAL OF LIPID RESEARCH

Ageing-related chromatin defects through loss of the NURD complex

(2009) Gianluca Pegoraro et al.   NATURE CELL BIOLOGY

Increased mechanosensitivity and nuclear stiffness in Hutchinson–Gilford progeria cells: effects of farnesyltransferase inhibitors

(2008) Valerie L. R. M. Verstraeten et al.   AGING CELL

Extreme phenotypic diversity and nonpenetrance in families with theLMNA gene mutation R644C

(2008) Julia Rankin et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Association of homozygousLMNAmutation R471C with new phenotype: Mandibuloacral dysplasia, progeria, and rigid spine muscular dystrophy

(2008) Birgit Zirn et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Identification of mutational hot spots in LMNA encoding lamin A/C in patients with familial dilated cardiomyopathy

(2008) Andreas Perrot et al.   BASIC RESEARCH IN CARDIOLOGY

The A- and B-type nuclear lamin networks: microdomains involved in chromatin organization and transcription

(2008) T. Shimi et al.   GENES & DEVELOPMENT

Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin

(2008) T. Dechat et al.   GENES & DEVELOPMENT

Eliminating the Synthesis of Mature Lamin A Reduces Disease Phenotypes in Mice Carrying a Hutchinson-Gilford Progeria Syndrome Allele

(2008) Shao H. Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear mechanotransduction: Response of the lamina to extracellular stress with implications in aging

(2008) Julia T. Philip et al.   JOURNAL OF BIOMECHANICS

Gone with the Wnt/Notch: stem cells in laminopathies, progeria, and aging

(2008) Eran Meshorer et al.   JOURNAL OF CELL BIOLOGY

Analysis of Prelamin A Biogenesis Reveals the Nucleus to be a CaaX Processing Compartment

(2008) Jemima Barrowman et al.   MOLECULAR BIOLOGY OF THE CELL

Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing

(2008) Paola Scaffidi et al.   NATURE CELL BIOLOGY

Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging

(2008) Ignacio Varela et al.   NATURE MEDICINE

Phenotype and Course of Hutchinson–Gilford Progeria Syndrome

(2008) Melissa A. Merideth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Novel LMNA Mutation in Atypical Werner Syndrome Presenting With Ischemic Disease

(2008) Dimitri Renard et al.   STROKE