Genomics, epigenomics and pharmacogenomics of familial hypercholesterolemia (FHBGEP): A study protocol
出版年份 2020 全文链接
标题
Genomics, epigenomics and pharmacogenomics of familial hypercholesterolemia (FHBGEP): A study protocol
作者
关键词
Familial hypercholesterolemia, Polygenic hypercholesterolemia, Genomics, Epigenomics, Pharmacogenomics
出版物
Research in Social & Administrative Pharmacy
Volume 17, Issue 7, Pages 1347-1355
出版商
Elsevier BV
发表日期
2020-10-29
DOI
10.1016/j.sapharm.2020.10.007
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- The familial hypercholesterolaemia phenotype: Monogenic familial hypercholesterolaemia, polygenic hypercholesterolaemia and other causes
- (2020) Cibelle Mariano et al. CLINICAL GENETICS
- The Potential for microRNA Therapeutics and Clinical Research
- (2019) Johora Hanna et al. Frontiers in Genetics
- The Impact of the International Cooperation On Familial Hypercholesterolemia Screening and Treatment: Results from the ScreenPro FH Project
- (2019) Richard Ceska et al. Current Atherosclerosis Reports
- Integrative roles of microRNAs in lipid metabolism and dyslipidemia
- (2019) Leslie R. Sedgeman et al. CURRENT OPINION IN LIPIDOLOGY
- Virtual screening of antibacterial compounds by similarity search of Enoyl-ACP reductase (FabI) inhibitors
- (2019) Leonardo Rander Asse Junior et al. Future Medicinal Chemistry
- DNA methylation in human lipid metabolism and related diseases
- (2018) Kirstin Mittelstraß et al. CURRENT OPINION IN LIPIDOLOGY
- Clinical utility of the polygenic LDL-C SNP score in familial hypercholesterolemia
- (2018) Marta Futema et al. ATHEROSCLEROSIS
- Clinical Genetic Testing for Familial Hypercholesterolemia
- (2018) Amy C. Sturm et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- KIF6 gene as a pharmacogenetic marker for lipid-lowering effect in statin treatment
- (2018) Cristina Ruiz-Iruela et al. PLoS One
- MicroRNAs: Novel Molecular Targets and Response Modulators of Statin Therapy
- (2018) Mohammad Mohajeri et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Long Noncoding RNAs in Atherosclerosis
- (2018) Zhengyi Zhang et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Safety and efficacy of statin therapy
- (2018) Bhavin B. Adhyaru et al. Nature Reviews Cardiology
- Role of flow-sensitive microRNAs and long noncoding RNAs in vascular dysfunction and atherosclerosis
- (2018) Sandeep Kumar et al. VASCULAR PHARMACOLOGY
- Emerging roles and mechanisms of long noncoding RNAs in atherosclerosis
- (2017) Yao Liu et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Polygenic Versus Monogenic Causes of Hypercholesterolemia Ascertained ClinicallyHighlights
- (2016) Jian Wang et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Long Noncoding RNAs in Cardiovascular Pathology, Diagnosis, and Therapy
- (2016) Christian Bär et al. CIRCULATION
- The panorama of familial hypercholesterolemia in Latin America: a systematic review
- (2016) Roopa Mehta et al. JOURNAL OF LIPID RESEARCH
- The genetic spectrum of familial hypercholesterolemia in south-eastern Poland
- (2016) Mahtab Sharifi et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- The role of DNA methylation in dyslipidaemia: A systematic review
- (2016) Kim V.E. Braun et al. PROGRESS IN LIPID RESEARCH
- Meta-analysis of Brazilian genetic admixture and comparison with other Latin America countries
- (2015) Ronald Rodrigues de Moura et al. AMERICAN JOURNAL OF HUMAN BIOLOGY
- Familial hypercholesterolemia in Brazil: Cascade screening program, clinical and genetic aspects
- (2015) Cinthia E. Jannes et al. ATHEROSCLEROSIS
- Familial hypercholesterolaemia: A global call to arms
- (2015) Antonio J. Vallejo-Vaz et al. ATHEROSCLEROSIS
- Normalization of circulating microRNA expression data obtained by quantitative real-time RT-PCR
- (2015) Francesco Marabita et al. BRIEFINGS IN BIOINFORMATICS
- Epigenetic-related therapeutic challenges in cardiovascular disease
- (2015) Concetta Schiano et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Presence and type of low density lipoprotein receptor (LDLR) mutation influences the lipid profile and response to lipid-lowering therapy in Brazilian patients with heterozygous familial hypercholesterolemia
- (2014) Paulo Caleb Junior Lima Santos et al. ATHEROSCLEROSIS
- Targeted genetic testing for familial hypercholesterolaemia using next generation sequencing: a population-based study
- (2014) Penny J Norsworthy et al. BMC Medical Genetics
- Epipolymorphisms within lipoprotein genes contribute independently to plasma lipid levels in familial hypercholesterolemia
- (2014) Simon-Pierre Guay et al. Epigenetics
- PyInteraph: A Framework for the Analysis of Interaction Networks in Structural Ensembles of Proteins
- (2014) Matteo Tiberti et al. Journal of Chemical Information and Modeling
- Genetic diagnosis of familial hypercholesterolaemia by targeted next-generation sequencing
- (2014) C. Maglio et al. JOURNAL OF INTERNAL MEDICINE
- Whole exome sequencing of familial hypercholesterolaemia patients negative forLDLR/APOB/PCSK9mutations
- (2014) Marta Futema et al. JOURNAL OF MEDICAL GENETICS
- MicroRNAs as Therapeutic Targets and Biomarkers of Cardiovascular Disease
- (2014) E. N. Olson Science Translational Medicine
- I Diretriz Brasileira de Hipercolesterolemia Familiar (HF)
- (2013) RD Santos et al. Arquivos Brasileiros de Cardiologia
- Genetics and Personalized Medicine—a Role in Statin Therapy?
- (2013) Jaideep Patel et al. Current Atherosclerosis Reports
- The use of next-generation sequencing in clinical diagnosis of familial hypercholesterolemia
- (2013) Jana Vandrovcova et al. GENETICS IN MEDICINE
- Polygenic familial hypercholesterolaemia: does it matter?
- (2013) Evan A Stein et al. LANCET
- Genome engineering using the CRISPR-Cas9 system
- (2013) F Ann Ran et al. Nature Protocols
- How good is automated protein docking?
- (2013) Dima Kozakov et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- In vitro functional characterization of missense mutations in the LDLR gene
- (2012) S. Silva et al. ATHEROSCLEROSIS
- Effectiveness of alternative strategies to define index case phenotypes to aid genetic diagnosis of familial hypercholesterolaemia
- (2012) Rosemary E J Clarke et al. HEART
- Use of targeted exome sequencing as a diagnostic tool for Familial Hypercholesterolaemia
- (2012) Marta Futema et al. JOURNAL OF MEDICAL GENETICS
- Cardiovascular epigenetics: From DNA methylation to microRNAs
- (2012) Silvia Udali et al. MOLECULAR ASPECTS OF MEDICINE
- Familial Hypercholesterolemias: Prevalence, genetics, diagnosis and screening recommendations from the National Lipid Association Expert Panel on Familial Hypercholesterolemia
- (2011) Paul N. Hopkins et al. Journal of Clinical Lipidology
- Promoter variant −204A > C of the cholesterol 7α-hydroxylase gene: Association with response to plant sterols in humans and increased transcriptional activity in transfected HepG2 cells
- (2010) Isabel De Castro-Orós et al. CLINICAL NUTRITION
- The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data
- (2010) A. McKenna et al. GENOME RESEARCH
- Identification of Heterogeneous Nuclear Ribonucleoprotein K as a Transactivator for Human Low Density Lipoprotein Receptor Gene Transcription
- (2010) Hai Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data
- (2010) K. Wang et al. NUCLEIC ACIDS RESEARCH
- Effects of APOE, APOB and LDLR variants on serum lipids and lack of association with xanthelasma in individuals from Southeastern Brazil
- (2009) Marcelo A. Nakazone et al. GENETICS AND MOLECULAR BIOLOGY
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