标题
Protease inhibition as new therapeutic strategy for GI diseases
作者
关键词
-
出版物
GUT
Volume 65, Issue 7, Pages 1215-1224
出版商
BMJ
发表日期
2016-04-13
DOI
10.1136/gutjnl-2015-309147
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Quantification and Potential Functions of Endogenous Agonists of Transient Receptor Potential Channels in Patients With Irritable Bowel Syndrome
- (2015) Nicolas Cenac et al. GASTROENTEROLOGY
- The functional and pathologic relevance of autophagy proteases
- (2015) Álvaro F. Fernández et al. JOURNAL OF CLINICAL INVESTIGATION
- Novel Role of the Serine Protease Inhibitor Elafin in Gluten-Related Disorders
- (2014) Heather J Galipeau et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Giardia duodenalis Cathepsin B Proteases Degrade Intestinal Epithelial Interleukin-8 and Attenuate Interleukin-8-Induced Neutrophil Chemotaxis
- (2014) James A. Cotton et al. INFECTION AND IMMUNITY
- Neutrophil Gelatinase B–associated Lipocalin and Matrix Metalloproteinase-9 Complex as a Surrogate Serum Marker of Mucosal Healing in Ulcerative Colitis
- (2014) Magali de Bruyn et al. INFLAMMATORY BOWEL DISEASES
- Cathepsin S Causes Inflammatory PainviaBiased Agonism of PAR2and TRPV4
- (2014) Peishen Zhao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Neutrophil-mediated Activation of Epithelial Protease-Activated Receptors-1 and -2 Regulates Barrier Function and Transepithelial Migration
- (2014) A. C. Chin et al. JOURNAL OF IMMUNOLOGY
- Remodelling the extracellular matrix in development and disease
- (2014) Caroline Bonnans et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Using human intestinal biopsies to study the pathogenesis of irritable bowel syndrome
- (2014) Y. Nasser et al. NEUROGASTROENTEROLOGY AND MOTILITY
- Giardia duodenalis Infection Reduces Granulocyte Infiltration in an In Vivo Model of Bacterial Toxin-Induced Colitis and Attenuates Inflammation in Human Intestinal Tissue
- (2014) James A. Cotton et al. PLoS One
- Microbial-induced meprin cleavage in MUC2 mucin and a functional CFTR channel are required to release anchored small intestinal mucus
- (2014) A. Schutte et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sensitization of Peripheral Sensory Nerves by Mediators From Colonic Biopsies of Diarrhea-Predominant Irritable Bowel Syndrome Patients: A Role for PAR2
- (2013) Eduardo E Valdez-Morales et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Engineering lactococci and lactobacilli for human health
- (2013) Luis G. Bermúdez-Humarán et al. CURRENT OPINION IN MICROBIOLOGY
- Characterisation of faecal protease activity in irritable bowel syndrome with diarrhoea: origin and effect of gut transit
- (2013) David Tooth et al. GUT
- Genetic and microbial factors modulating the ubiquitin proteasome system in inflammatory bowel disease
- (2013) Isabelle Cleynen et al. GUT
- High Expression of the “A Disintegrin And Metalloprotease” 19 (ADAM19), a Sheddase for TNF-α in the Mucosa of Patients with Inflammatory Bowel Diseases
- (2013) Eleonora Franzè et al. INFLAMMATORY BOWEL DISEASES
- Site-specificO-Glycosylation on the MUC2 Mucin Protein Inhibits Cleavage by thePorphyromonas gingivalisSecreted Cysteine Protease (RgpB)
- (2013) Sjoerd van der Post et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The gastrointestinal mucus system in health and disease
- (2013) Malin E. V. Johansson et al. Nature Reviews Gastroenterology & Hepatology
- Fecal Protease Activity Is Associated with Compositional Alterations in the Intestinal Microbiota
- (2013) Ian M. Carroll et al. PLoS One
- Missing the target: matrix metalloproteinase antitargets in inflammation and cancer
- (2013) Antoine Dufour et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Enteric bacterial proteases in inflammatory bowel disease- pathophysiology and clinical implications
- (2013) Ian M Carroll WORLD JOURNAL OF GASTROENTEROLOGY
- SLPI and elafin: multifunctional antiproteases of the WFDC family
- (2012) Aaron Scott et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Effects of cathepsin K deficiency on intercellular junction proteins, luminal mucus layers, and extracellular matrix constituents in the mouse colon
- (2012) Maria Arampatzidou et al. BIOLOGICAL CHEMISTRY
- Proteases and the gut barrier
- (2012) Paolo Biancheri et al. CELL AND TISSUE RESEARCH
- Lactocepin Secreted By Lactobacillus Exerts Anti-Inflammatory Effects By Selectively Degrading Proinflammatory Chemokines
- (2012) Marie-Anne von Schillde et al. Cell Host & Microbe
- The Impact of Matrix Metalloproteinases and Their Tissue Inhibitors in Inflammatory Bowel Diseases
- (2012) Gábor Lakatos et al. DIGESTIVE DISEASES
- Tissue Inhibitor of Metalloproteinase-3 Regulates Inflammation in Human and Mouse Intestine
- (2012) Ivan Monteleone et al. GASTROENTEROLOGY
- Identifying and testing candidate genetic polymorphisms in the irritable bowel syndrome (IBS): association with TNFSF15 and TNFα
- (2012) Caroline Swan et al. GUT
- Cleavage of IgG1 in gingival crevicular fluid is associated with the presence ofPorphyromonas gingivalis
- (2012) A. Guentsch et al. JOURNAL OF PERIODONTAL RESEARCH
- Food-Grade Bacteria Expressing Elafin Protect Against Inflammation and Restore Colon Homeostasis
- (2012) J.-P. Motta et al. Science Translational Medicine
- Serine Protease(s) Secreted by the Nematode Trichuris muris Degrade the Mucus Barrier
- (2012) Sumaira Z. Hasnain et al. PLoS Neglected Tropical Diseases
- Modifying the Protease, Antiprotease Pattern by Elafin Overexpression Protects Mice From Colitis
- (2011) Jean–Paul Motta et al. GASTROENTEROLOGY
- Activity of Protease-Activated Receptors in the Human Submucous Plexus
- (2011) Kerstin Mueller et al. GASTROENTEROLOGY
- Matriptase Protects Against Experimental Colitis and Promotes Intestinal Barrier Recovery
- (2011) Sarah Netzel-Arnett et al. INFLAMMATORY BOWEL DISEASES
- Inflammatory Skin and Bowel Disease Linked toADAM17Deletion
- (2011) Diana C. Blaydon et al. NEW ENGLAND JOURNAL OF MEDICINE
- Genetic Evidence Supporting the Association of Protease and Protease Inhibitor Genes with Inflammatory Bowel Disease: A Systematic Review
- (2011) Isabelle Cleynen et al. PLoS One
- Subjects with Diarrhea-Predominant IBS Have Increased Rectal Permeability Responsive to Tryptase
- (2010) Jae Woong Lee et al. DIGESTIVE DISEASES AND SCIENCES
- TNF is a key mediator of the pronociceptive effects of mucosal supernatant from human ulcerative colitis on colonic DRG neurons
- (2010) C. Ibeakanma et al. GUT
- Elastase 2 is expressed in human and mouse epidermis and impairs skin barrier function in Netherton syndrome through filaggrin and lipid misprocessing
- (2010) Chrystelle Bonnart et al. JOURNAL OF CLINICAL INVESTIGATION
- The paradox of the neutrophilˈs role in tissue injury
- (2010) George B. Segel et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Lactobacillus and Bifidobacterium species do not secrete protease that cleaves the MUC2 mucin which organises the colon mucus
- (2010) D. Subramani et al. Beneficial Microbes
- Increased Proteasome-Mediated Degradation of Occludin in Irritable Bowel Syndrome
- (2009) Moïse Coëffier et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Serine proteases decrease intestinal epithelial ion permeability by activation of protein kinase Cζ
- (2009) Veronica A. Swystun et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Differential expression and regulation of ADAM17 and TIMP3 in acute inflamed intestinal epithelia
- (2009) Annabelle Cesaro et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Activation of Human Enteric Neurons by Supernatants of Colonic Biopsy Specimens From Patients With Irritable Bowel Syndrome
- (2009) Sabine Buhner et al. GASTROENTEROLOGY
- Protease-activated receptor-4 (PAR4): a role as inhibitor of visceral pain and hypersensitivity
- (2009) c. augé et al. NEUROGASTROENTEROLOGY AND MOTILITY
- Fecal proteases from diarrheic-IBS and ulcerative colitis patients exert opposite effect on visceral sensitivity in mice
- (2009) Anita Annaházi et al. PAIN
- Protease-activated receptors as drug targets in inflammation and pain
- (2009) Nathalie Vergnolle PHARMACOLOGY & THERAPEUTICS
- Tumor-associated and microbial proteases compromise host IgG effector functions by a single cleavage proximal to the hinge
- (2009) R. J. Brezski et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Transient Receptor Potential Vanilloid-4 Has a Major Role in Visceral Hypersensitivity Symptoms
- (2008) Nicolas Cenac et al. GASTROENTEROLOGY
- Selective Role for TRPV4 Ion Channels in Visceral Sensory Pathways
- (2008) Stuart M. Brierley et al. GASTROENTEROLOGY
- Impaired intestinal barrier integrity in the colon of patients with irritable bowel syndrome: involvement of soluble mediators
- (2008) T Piche et al. GUT
- Proteinase-activated receptors (PARs) in infection and inflammation in the gut
- (2008) N VERGNOLLE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Trypsinogen IV, serotonin transporter transcript levels and serotonin content are increased in small intestine of irritable bowel syndrome patients
- (2008) a. p. m. kerckhoffs et al. NEUROGASTROENTEROLOGY AND MOTILITY
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