Review
Chemistry, Multidisciplinary
Jan Krajczewski, Robert Ambroziak, Andrzej Kudelski
Summary: Surface-Enhanced Raman Scattering (SERS) refers to the phenomenon where the efficiency of generating Raman spectra by molecules adsorbed on some substrates is many orders of magnitude larger than those that are not adsorbed. Significant advances have been made in utilizing nanostructured non-metallic materials as SERS substrates, showing great potential for future applications.
Article
Chemistry, Multidisciplinary
Makayla M. Schmidt, Emily A. Farley, Marit A. Engevik, Trey N. Adelsman, Ariadne Tuckmantel Bido, Nathan D. Lemke, Alexandre G. Brolo, Nathan C. Lindquist
Summary: The concept of plasmonic hotspots is central to nanophotonics, specifically in surface-enhanced Raman scattering (SERS). SERS signals from single molecules often exhibit fluctuations, challenging the concept of static hotspots. Recent experiments have shown SERS intensity fluctuations (SIFs) to occur over a wide range of timescales due to various physical mechanisms causing SERS and the dynamic nature of light-matter interaction. This study presents a high-speed acquisition system that captures SERS spectra with microsecond time resolution, revealing that high-speed SIF events occur with relatively equal probability over a broad spectral range.
Article
Chemistry, Multidisciplinary
Makayla M. Schmidt, Emily A. Farley, Marit A. Engevik, Trey N. Adelsman, Ariadne Tuckmantel Bido, Nathan D. Lemke, Alexandre G. Brolo, Nathan C. Lindquist
Summary: The concept of plasmonic hotspots plays a crucial role in the field of nanophotonics, particularly in surface-enhanced Raman scattering (SERS). Recent experiments have shown that these hotspots exhibit significant fluctuations at different timescales, which are likely caused by the complex interplay of multiple effects. This study presents a high-speed acquisition system that captures the dynamic processes of SERS fluctuations and finds that these fluctuations occur over a wide spectral range.
Article
Biochemistry & Molecular Biology
Giuseppe La Verde, Antonio Sasso, Giulia Rusciano, Angela Capaccio, Sabato Fusco, Laura Mayol, Marco Biondi, Teresa Silvestri, Paolo A. A. Netti, Marco La Commara, Valeria Panzetta, Mariagabriella Pugliese
Summary: Poly(lactide-co-glycolide) (PLGA) nanoparticles coated with hyaluronic acid (HA) were synthesized and analyzed using Dynamic Light Scattering (DLS) and Surface-Enhanced Raman Scattering (SERS) spectroscopy to characterize their physico-chemical properties and stability over time.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Chemistry, Analytical
Jan Jehlicka, Howell G. M. Edwards, Aharon Oren
Summary: This review discusses the application of Raman spectroscopy in studying violet and brown pigments produced by microorganisms. Raman spectroscopy is a widely appreciated analytical tool in the field of microbiology and chemistry, and its recent developments have opened up new possibilities for studying microbial colonization in natural geobiological systems.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2022)
Review
Instruments & Instrumentation
E. Akanny, A. Bonhomme, F. Bessueille, S. Bourgeois, C. Bordes
Summary: SERS technique has been widely used in bacteria analysis, offering advantages in terms of analysis time, sensitivity, and sample preparation compared to traditional bacteria culture methods. Over the past 20 years, various SERS methods have been developed for bacteria analysis, with a comprehensive study of related technical issues.
APPLIED SPECTROSCOPY REVIEWS
(2021)
Article
Chemistry, Physical
Tiago Fernandes, Sara Fateixa, Marta Ferro, Helena I. S. Nogueira, Ana L. Daniel-da-Silva, Tito Trindade
Summary: The use of dendrimers in the controlled synthesis of Ag:Au hybrid nanostructures enhances SERS sensitivity to organic pollutants. Dendrimers play a crucial role as multipurpose ligands in the formation of hybrid nanostructures, improving stability and sensitivity. Interparticle plasmonic coupling templated by dendrimer macromolecules contributes to the high SERS sensitivity of the hybrid nanostructures.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Chemistry, Analytical
Olga E. Eremina, Olesya O. Kapitanova, Alexei V. Medved'ko, Alexandra S. Zelenetskaya, Bayirta V. Egorova, Tatyana N. Shekhovtsova, Sergey Z. Vatsadze, Irina A. Veselova
Summary: In this study, a novel indicator system based on the formation of mixed ligand complexes was proposed, which can stabilize the complexes of catecholamines and shift their maximum absorbance to the visible range. This allowed the measurement of intense Raman signals on a nanostructured silver-based SERS-active substrate. The developed system facilitated the determination of dopamine over a wide concentration range.
Article
Chemistry, Multidisciplinary
Takashi Fujita, Kohei Shibamoto
Summary: Uniform 2D arrays of metal nanoparticles can be formed using the sandwich technique, which is an important development in molecular sensing. The drying conditions during the formation process play a crucial role in obtaining a uniform and ideal array structure. These 2D arrays of metal nanoparticles exhibit excellent spot-to-spot reproducibility in surface-enhanced Raman scattering.
Article
Chemistry, Multidisciplinary
Takashi Fujita, Kohei Shibamoto
Summary: Uniform and non-aggregated two-dimensional arrays of metal nanoparticles have been successfully formed using the sandwich technique, and they exhibit excellent spot-to-spot reproducibility in surface-enhanced Raman scattering. Optimal drying conditions and hexagonal periodicity of nanoparticle arrangement were obtained for the formation of these arrays.
Review
Chemistry, Analytical
Mohamed O. Amin, Entesar Al-Hetlani, Igor K. Lednev
Summary: Fingermark analysis is a key tool in criminal investigation, and the biochemical composition of FMs has attracted considerable attention as a vital source of forensic evidence. Vibrational spectroscopy is used to better understand the chemistry of latent FMs and improve detection methods. The article critically reviews the advances in FM analysis using vibrational spectroscopic techniques over the past 10 years, highlighting current limitations and discussing ways to overcome them to support the development of FM analysis techniques meeting modern forensic science requirements.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2021)
Article
Spectroscopy
Karlis Berzins, Samuel D. L. Harrison, Claudia Leong, Sara J. Fraser-Miller, Michelle J. Harper, Aly Diana, Rosalind S. Gibson, Lisa A. Houghton, Keith C. Gordon
Summary: Raman and ATR-FTIR spectroscopy were used to analyze 208 breast milk samples as part of a larger research study. Comprehensive qualitative and quantitative analysis was carried out using chemometric methods, revealing the relationship between macronutrients and sample metadata. The study location and primary food sources were found to have a stronger impact on fat composition than its absolute content, highlighting the limitations and challenges of using spectroscopic techniques for this type of analysis.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Chemistry, Multidisciplinary
Aditya Garg, Elieser Mejia, Wonil Nam, Peter Vikesland, Wei Zhou
Summary: A high-throughput reverse nanoimprint lithography approach has been developed to create biomimetic transparent nanoplasmonic microporous mesh (BTNMM) devices with ultrathin flexible microporous structures for spatiotemporal multimodal surface-enhanced Raman spectroscopy (SERS) measurements at the bio-interface.
Article
Chemistry, Analytical
Cai-jun Wu, Si-qi Huang, Yu-ying Wang, Ya-qin Chai, Ruo Yuan, Xia Yang
Summary: The study involves stabilizing self-assembled Au NPs on the liquid-liquid interface using DNA structures, combined with DNA recycling amplification strategy to construct a liquid-phase SERS biosensor for efficient detection of miRNA 155. Compared to traditional methods, the SERS signal is significantly enhanced, detection limit is lower, and linear range wider.
ANALYTICAL CHEMISTRY
(2021)
Article
Engineering, Environmental
Ting Wang, Shuangpeng Wang, Zehua Cheng, Jinchao Wei, Lele Yang, Zhangfeng Zhong, Hao Hu, Yitao Wang, Bingpu Zhou, Peng Li
Summary: Pesticide residues pose a significant threat to human health and the environment, driving the need for rapid and effective detection methods. Core-shell nanostructures as novel SERS substrates have been widely utilized in rapid pesticide detection research. Understanding and monitoring pesticide residues can be improved through the classification and evaluation of different core-shell nanostructures and early-warning analysis.
CHEMICAL ENGINEERING JOURNAL
(2021)
Editorial Material
Chemistry, Multidisciplinary
Alberto Tagliaferro, Elisa Padovano, Mattia Bartoli, Mauro Giorcelli
Article
Biochemistry & Molecular Biology
Justin B. Domena, Ermin Celebic, Braulio C. L. B. Ferreira, Yiqun Zhou, Wei Zhang, Jiuyan Chen, M. Bartoli, A. Tagliaferro, Qiaxian Johnson, Bhanu P. S. Chauhan, Victor Paulino, Jean-Hubert Olivier, Roger M. Leblanc
Summary: In this study, a NIR emitting dye, p-toluenesulfonate (IR-813) was used as a model precursor to develop red emissive carbon dots (813-CD) with solvatochromic behavior. The emission peaks of 813-CD in water blue shifted as solvent polarity decreased. By increasing the nitrogen content with polyethyleneimine (PEI), the band gap energy of the CDs increased and the emission could reach as far as 776 nm. A CD nanocomposite polyvinylpyrrolidone (PVP) film was synthesized to investigate solid-state fluorescence. The CDs also showed electrochemical properties and could be used as doping agents for PVP film coatings.
Review
Biochemistry & Molecular Biology
Marco Giuseppe Giordano, Giulia Seganti, Mattia Bartoli, Alberto Tagliaferro
Summary: Carbon quantum dots are a new era material with remarkable properties, including high photoluminescence, chemical tuneability, and high biocompatibility. However, their classification and the explanation of their optical properties and chemical structure are still subjects of debate. This review aims to provide a clear discussion on these points, serving as a starting point for the rationalization of their classification and a comprehensive understanding of the optical and chemical features of carbon quantum dots.
Article
Biochemistry & Molecular Biology
Mattia Bartoli, Elena Marras, Alberto Tagliaferro
Summary: The study of carbon dots is at the forefront of materials science. The production of solid models that accurately describe the chemical and physical features of carbon dots has been slow due to their complexity. Recent advancements have addressed this challenge by providing structural-based interpretations for different types of carbon dots. Computational studies on the interaction between carbon dots and bioactive molecules have also been conducted. In this work, the structures of carbon nitride dots and their interaction with an anticancer molecule (Doxorubicin) were modeled and evaluated using semi-empirical methods.
Article
Polymer Science
Mattia Di Maro, Maria Giulia Faga, Riccardo Pedraza, Giulio Malucelli, Mattia Bartoli, Giovanna Gomez d'Ayala, Donatella Duraccio
Summary: This study investigates the combination of hemp-derived biochar and commercial humic acid as a potential flame-retardant system for ethylene vinyl acetate copolymer. The results show that the addition of biochar significantly improves the thermal stability of the copolymer, while the acidic nature of humic acid leads to degradation. Furthermore, the incorporation of biochar reduces heat release during combustion and prolongs burning time, while humic acid has little effect on combustion performance.
Review
Polymer Science
Mattia Bartoli, Erik Piatti, Alberto Tagliaferro
Summary: The development of new scaffolds and materials for tissue engineering is a wide and open realm of material science. Among solutions, the use of biopolymers represents a particularly interesting area of study due to their great chemical complexity that enables creation of specific molecular architectures. However, biopolymers do not exhibit the properties required for direct application in tissue repair-such as mechanical and electrical properties-but they do show very attractive chemical functionalities which are difficult to produce through in vitro synthesis. The combination of biopolymers with nanostructured carbon fillers could represent a robust solution to enhance composite properties, producing composites with new and unique features, particularly relating to electronic conduction. In this paper, we provide a review of the field of carbonaceous nanostructure-containing biopolymer composites, limiting our investigation to tissue-engineering applications, and providing a complete overview of the recent and most outstanding achievements.
Article
Chemistry, Analytical
Silvia Zecchi, Fabrizio Ruscillo, Giovanni Cristoforo, Mattia Bartoli, Griffin Loebsack, Kang Kang, Erik Piatti, Daniele Torsello, Gianluca Ghigo, Roberto Gerbaldo, Mauro Giorcelli, Franco Berruti, Alberto Tagliaferro
Summary: By mixing red mud with hemp waste, biochar with high conductivity and good magnetic properties can be produced through carbothermal processes. The resulting biochar enriched with thermally-reduced red mud is then used to prepare epoxy-based composites, which are tested for their electric and magnetic properties.
Article
Chemistry, Multidisciplinary
Luca Lavagna, Andrea Santagati, Mattia Bartoli, Daniel Suarez-Riera, Matteo Pavese
Summary: The dispersion and interaction of graphene in the cement matrix can be improved by oxidizing graphene with sulfonitric acid. This oxidation process enhances the mechanical and electrical properties of the final cement composites.
Review
Chemistry, Physical
Mattia Bartoli, Mauro Giorcelli, Alberto Tagliaferro
Summary: This review provides a comprehensive overview of the most cutting-edge applications of biochar-based catalysts, serving as a reference point for both experts and newcomers. It describes all possible applications of biochar-based catalysts, demonstrating their sustainability for a wide range of processes.
Article
Chemistry, Multidisciplinary
Alessio Mezza, Mattia Bartoli, Angelica Chiodoni, Juqin Zeng, Candido F. Pirri, Adriano Sacco
Summary: Gas-fed reactors for CO2 reduction are effective in mitigating CO2 accumulation, but the separation process of CO2 from flue gases is energy-demanding. Bicarbonate zero-gap flow reactors can integrate carbon capture and valorization, converting the bicarbonate solution into valuable chemicals to avoid expensive separation. This study investigates the influence of electrode structure on bicarbonate reactor performance, discovering a low-loaded silver-based electrode with enhanced selectivity and activity.
Article
Chemistry, Multidisciplinary
Erik Piatti, Daniele Torsello, Gaia Gavello, Gianluca Ghigo, Roberto Gerbaldo, Mattia Bartoli, Donatella Duraccio
Summary: The combination of conductive carbon and magnetic particles is an effective strategy to produce advanced fillers for polymer composites that can shield against microwave radiation. In this study, an iron-tailored biochar obtained from olive pruning pyrolysis was developed and characterized as a filler for epoxy composites. Extensive characterization was conducted to evaluate the electrical and magnetic properties of biochar-based composites with and without iron. The results showed that the composites with higher filler loading exhibited higher DC electrical conductivity and ferromagnetic behavior.
Article
Engineering, Electrical & Electronic
Francesca Rodino, Mattia Bartoli, Sandro Carrara
Summary: Etoposide (ETO) and methotrexate (MTX) are chemotherapy drugs used in cancer treatment, but their narrow therapeutic window can lead to significant adverse effects. Therapeutic drug monitoring (TDM) is important for optimizing treatment outcomes, adjusting dosage, and minimizing adverse effects. The electrochemical interaction between ETO and MTX during simultaneous detection has not been studied, and our study aims to investigate their oxidation mechanism during simultaneous detection on the same sensor.
IEEE SENSORS LETTERS
(2023)
Article
Chemistry, Physical
Mallikarjun Madagalam, Mattia Bartoli, Michele Rosito, Nicola Blangetti, Marco Etzi Coller Pascuzzi, Elisa Padovano, Barbara Bonelli, Sandro Carrara, Alberto Tagliaferro
Summary: To deepen the understanding of electron transfer at the electrochemical interface, the performance of ZnxNi1-xFe2O4 (x = 0, 0.2, 0.4, 0.6, 0.8, 1) nanomaterials in electrochemical sensing was studied. Nanomaterials were synthesized using a simple autocombustion synthesis procedure. The ZnFe2O4 sensor showed the best performances in terms of rate constant, peak-to-peak separation, sensitivity, and detection limit. Nanomaterials energy bands mapping with the experimental redox potentials was performed to predict electron transfer. The importance of surface states/defects in the electron transfer mechanism was highlighted.
Proceedings Paper
Engineering, Biomedical
Mallikarjun Madagalam, Mattia Bartoli, Sandro Carrara, Alberto Tagliaferro
Summary: In this study, screen-printed carbon-based electrochemical sensors modified with ZnMxFe2-xO4 were developed and their performance in electrochemical sensing of paracetamol was investigated. The sensitivity and first-order kinetic rate constant of 6 types of sensors were compared, showing significant improvement compared to the bare carbon sensor. Among the new sensors, ZnFe2O4 exhibited the highest sensitivity and rate constant, while ZnBi2O4 showed the lowest.
2023 IEEE BIOSENSORS CONFERENCE, BIOSENSORS
(2023)
