Article
Biology
Suraj B. Patel, Savaliram G. Ghane
Summary: The study revealed that the fruit and leaves of L. echinata are rich in bioactive compounds, showing potential as natural antioxidants, antidiabetic, and anticancer agents.
SAUDI JOURNAL OF BIOLOGICAL SCIENCES
(2021)
Review
Plant Sciences
Jiao Wang, Neeraj Rani, Seema Jakhar, Rakesh Redhu, Sanjiv Kumar, Sachin Kumar, Sanjeev Kumar, Bhagwati Devi, Jesus Simal-Gandara, Bairong Shen, Rajeev K. Singla
Summary: This article reviews the anticancer properties of Opuntia ficus-indica (L.) Mill. and its potential as a natural cancer prevention and treatment agent. The study highlights the mechanisms involved, such as apoptosis, cell cycle arrest, and Bcl-2 modulation. However, further research is needed to determine the clinical utility of this resource.
FRONTIERS IN PLANT SCIENCE
(2023)
Review
Biochemistry & Molecular Biology
Erick Bahena Culhuac, Aristide Maggiolino, Mona M. M. Y. Elghandour, Pasquale De Palo, Abdelfattah Z. M. Salem
Summary: The Yucca genus, native to North America, has been used in traditional medicine for its antioxidant and anti-inflammatory properties. However, research on this genus is limited. This study aimed to analyze the phytochemical composition and the mechanisms of action behind these properties. The results showed that the antioxidant and anti-inflammatory effects are mainly due to free radical scavenging activity, inhibition of arachidonic acid metabolism, and modulation of various cytokines and enzymes. More studies are needed to fully understand the potential of Yucca genus in managing chronic inflammation.
Review
Food Science & Technology
Fang Wang, Yifan Bao, Chen Zhang, Libin Zhan, Washim Khan, Sahifa Siddiqua, Sayeed Ahmad, Esra Capanoglu, Krystyna Skalicka-Wozniak, Liang Zou, Jesus Simal-Gandara, Hui Cao, Zebin Weng, Xinchun Shen, Jianbo Xiao
Summary: Moringa oleifera, a tropical deciduous tree, has high economic and pharmaceutical value. It is rich in nutrients and bioactive phytochemicals, attracting attention for its anti-diabetic properties. Recent studies have reported numerous new chemical structures and pharmacological activities related to Moringa oleifera's anti-diabetic properties. This review summarizes the bioactive phytochemicals present in M. oleifera and provides experimental and clinical evidence, along with underlying mechanisms, for its therapeutic potential in diabetes. Insights gained from this review can contribute to the development of novel drugs.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Nutrition & Dietetics
A. Lum Han, Su-Ji Jeong, Myeong-Seon Ryu, Hee-Jong Yang, Do-Youn Jeong, Do-Sim Park, Hee Kyung Lee
Summary: The study found that Kochujang, a traditional Korean chili paste, has anti-obesity effects in cell and animal models. In experiments with overweight and obese adults, consumption of Kochujang resulted in reduced waist circumference, decreased cholesterol levels, and decreased visceral fat. The presence of beneficial microbes in Kochujang also played a role in improving lipid profiles.
Review
Nutrition & Dietetics
Qingzheng Kang, Haiyu Dai, Suwei Jiang, Li Yu
Summary: AGEs play important pathogenic roles in the development of diabetic retinopathy, including metabolic abnormalities, oxidative stress, and cytopathic effects. The interaction between AGEs and RAGE leads to various pathological alterations in retinal cells. Targeting disorders associated with AGEs and exploring the use of antioxidant phytochemicals as therapeutic strategies show potential for the treatment of diabetic retinopathy.
FRONTIERS IN NUTRITION
(2022)
Article
Food Science & Technology
Piya Temviriyanukul, Suwapat Kittibunchakul, Piyapat Trisonthi, Woorawee Inthachat, Dalad Siriwan, Uthaiwan Suttisansanee
Summary: Thailand grows a wide variety of tropical fruits with potential phytonutrients, anti-obesity, anti-diabetes, anti-mutagenic, and chemopreventive effects. Some fruit extracts showed high antioxidant activity and inhibition of key enzymes related to obesity and diabetes. Additionally, they demonstrated suppression of DNA mutations and cancer promotion, suggesting their potential health benefits.
Article
Food Science & Technology
Tapan Behl, Keshav Kumar, Sukhbir Singh, Aayush Sehgal, Monika Sachdeva, Saurabh Bhatia, Ahmed Al-Harrasi, Camelia Buhas, Claudia Teodora Judea-Pusta, Nicoleta Negrut, Mihai Alexandru Munteanu, Ciprian Brisc, Simona Bungau
Summary: Diabetes retinopathy (DR) is a common microvascular complication of diabetes, leading to blindness, and the current available therapies lack long-term efficacy and safety assessment. Therefore, there is a need to find more reliable and effective treatments, with plant-derived polyphenols showing promise as an alternative option.
JOURNAL OF FUNCTIONAL FOODS
(2021)
Review
Chemistry, Medicinal
Naiara Cassia Gancedo, Raquel Isolani, Natalia Castelhano de Oliveira, Celso Vataru Nakamura, Daniela Cristina de Medeiros Araujo, Andreia Cristina Conegero Sanches, Fernanda Stumpf Tonin, Fernando Fernandez-Llimos, Danielly Chierrito, Joao Carlos Palazzo de Mello
Summary: This study aimed to synthesize the anticancer and anti-proliferative potential of Limonium species through a systematic review. The results indicate that Limonium species have the potential to be a source of new potential cytotoxic and anticancer agents. However, further research and improved experimental designs are needed to better understand the mechanism of action of these compounds.
Article
Biochemistry & Molecular Biology
Fatima Rashid, Anam Javaid, Mahmood-ur-Rahman, Usman Ali Ashfaq, Muhammad Sufyan, Abdulrahman Alshammari, Metab Alharbi, Muhammad Atif Nisar, Mohsin Khurshid
Summary: This study evaluated the anti-diabetic potential of Syzygium cumini plant's seeds and identified two phytochemicals (kaempferol and gallic acid) with strong inhibitory capacity against alpha-glucosidase. These phytochemicals demonstrated superior binding energy, protein-ligand interaction, and MD simulation results compared to the standard drug acarbose. The ADMET properties of gallic acid and kaempferol also met safety criteria. Therefore, S. cumini and its bioactive compounds have the potential to be used as a treatment for diabetes.
Article
Integrative & Complementary Medicine
B. Thanuja, R. Parimalavalli, S. Vijayanand, Reem Mohammed Alharbi, Neveen Abdel-Raouf, Ibraheem Borie M. Ibraheem, Essam Nageh Sholkamy, Kaliannan Durairaj, Kibrom Meansbo Hadish
Summary: This study evaluated the cytotoxicity of black rice flour against colon cancer and mouse embryo cells, and found that native black rice flour exhibited significant cytotoxicity and anticancer potential against human colon cancer cells. Additionally, black rice flour showed weak cytotoxicity in mouse embryo cells.
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
(2022)
Article
Engineering, Chemical
Salman Khan, Zeeshan Rafi, Abu Baker, Ambreen Shoaib, Ali G. Alkhathami, Mohammed Asiri, Mohammad Y. Alshahrani, Irfan Ahmad, Yasser Alraey, Ali Hakamy, Mohd Saeed, Shazia Mansoor
Summary: Known for its high nutritional and medicinal value, okra (Abelmoschus esculentus) is a major economic crop cultivated worldwide. This study investigated the nutritional properties and potential applications of okra. Results showed that okra contained various nutrients, including minerals, carbohydrates, proteins, and fiber. It also exhibited antimicrobial, anticancer, and antioxidant properties. The findings suggest that okra can be used as a functional food and nutraceutical supplement.
Article
Biochemistry & Molecular Biology
Bisma Meer, Anisa Andleeb, Junaid Iqbal, Hajra Ashraf, Kushif Meer, Joham Sarfraz Ali, Samantha Drouet, Sumaira Anjum, Azra Mehmood, Taimoor Khan, Mohammad Ali, Christophe Hano, Bilal Haider Abbasi
Summary: This study successfully synthesized zinc oxide nanoparticles using the seed extract of Lepidium sativum through bio-assisted synthesis. The synthesized nanoparticles were characterized using various spectroscopy and imaging techniques and were tested for various in vitro biological assays. The results showed that the bio-assisted zinc oxide nanoparticles exhibited excellent antioxidant, antibacterial, and potential in cancer therapeutics.
Article
Biochemistry & Molecular Biology
Rabia Betul Aygun, Gokhan Zengin, Evren Yildiztugay, Sharmeen Jugreet, Mustafa Abdullah Yilmaz, Fawzi Mohamad Mahomoodally
Summary: This study evaluated the phytochemical, antioxidant, and anti-enzymatic properties of extracts from Silene caramanica and S. otites. The extracts exhibited antioxidant and enzyme inhibition activities, indicating their potential pharmacological properties.
PROCESS BIOCHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Hun Hwan Kim, Sang Eun Ha, Preethi Vetrivel, Pritam Bhagwan Bhosale, Seong Min Kim, Gon Sup Kim
Summary: This study systematically analyzed the antioxidant and anti-inflammatory potentials of polyphenols contained in Gynura procumbens (GP) extract, identifying major active compounds such as caffeic acid, kynurenic acid, and chlorogenic acid. Additionally, the anti-inflammatory effect of GP was confirmed in vitro.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Food Science & Technology
Song Li, Jielun Hu, Haoyingye Yao, Fang Geng, Shaoping Nie
Summary: This review explores the effects of different galactans on gut microbiota and the production of short-chain fatty acids. It summarizes the structural characteristics of four types of galactans and discusses the ability of gut microbiota to utilize them. The findings suggest potential applications of galactans as functional foods.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Review
Food Science & Technology
Yingying Feng, Teketay Wassie, Renyou Gan, Xin Wu
Summary: Marine algae are an important untapped source of functional food, with sulfated polysaccharides exhibiting various bioactivities, particularly immunomodulation.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Review
Food Science & Technology
Yu Chen, Liyong Luo, Shanshan Hu, Renyou Gan, Liang Zeng
Summary: This review explores the anti-hyperuricemia effect and mechanisms of tea. Tea intake is associated with a lower risk of hyperuricemia, especially polyphenols. Tea exhibits alleviating effects on hyperuricemia by inhibiting uric acid production, activating Nrf2, and regulating uric acid transporters. A desirable tea intake of about 5 g/day may be beneficial for preventing hyperuricemia.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Review
Food Science & Technology
Changyu Zhou, Qiang Xia, Lihui Du, Jun He, Yangying Sun, Yali Dang, Fang Geng, Daodong Pan, Jinxuan Cao, Guanghong Zhou
Summary: This review discusses the formation mechanism of off-odor in dry-cured ham and the potential regulation of off-odor defects using starter cultures. Current research shows that various spoilage microorganisms and metabolites play a key role in the development of off-odor in dry-cured ham. Starter cultures derived from species such as Staphylococcus, Penicillium, Debaryomyces, Pediococcus, and Lactobacillus have shown potential in preventing microbiological hazards and improving flavor quality.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Food Science & Technology
Hongmin Dai, Fuchao Zhan, Yijie Chen, Qian Shen, Fang Geng, Ziyang Zhang, Bin Li
Summary: The study demonstrated that pH shift treatment significantly improved the solubility and emulsification of rice protein isolate under neutral conditions. The treatment led to decreased particle size, changes in protein structure, and enhanced emulsion stability. Overall, the method improved the structural and functional properties of the protein for food applications.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Chemistry, Applied
Xiaoqi He, Jinqiu Wang, Yi Wang, Beibei Wang, Jiamin Zhang, Fang Geng
Summary: This study quantitatively analyzed the lipid composition of chicken egg yolk (EY), yolk granule (EYG), and yolk plasma (EYP) using liquid chromatography-tandem mass spectrometry. The results revealed that phospholipids were the representative differentially abundant lipids between EY and EYG, EY and EYP, while triglycerides were the most representative differentially abundant lipids between EYG and EYP.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2023)
Article
Agriculture, Multidisciplinary
Xinping Chang, Yu Xiao, Lei Cheng, Xuedong Gu, Lin Yang, Yangzom Chamba, Jiamin Zhang, Fang Geng
Summary: This study compared the protein profiles in the livers of three different Yorkshire pig breeds (SNY, LZY, JZY) using quantitative proteomics. A total of 6804 proteins were identified, 6471 of which were quantified, and 774 differentially expressed proteins (DEPs) were identified. The study found that LZY pigs had higher energy metabolism levels in response to high altitudes, while SNY pigs had suppressed energy output. The liver of Yorkshire pigs locally regulated antioxidant enzymes and showed differential expression of ribosomal proteins in different altitudinal environments.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Editorial Material
Infectious Diseases
Junyan Liu, Zhenbo Xu, Yulong Tan, Ren-You Gan, Guanggang Qu, Dingqiang Chen
Review
Food Science & Technology
Huan Guo, Hong-Yan Liu, Hang Li, Ding-Tao Wu, Linda L. D. Zhong, Ren-You Gan, Hong Gao
Summary: This study discusses and compares the effects of different drying processes on the chemical composition, structural, and biological properties of plant polysaccharides. It also emphasizes that the biological properties of polysaccharides are determined by multiple factors, providing a fundamental theoretical basis for the structure-function relationship of these compounds.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Biochemistry & Molecular Biology
Jia-Ying Zhao, Tao Hong, Yan-Jie Hou, Xiao-Xiao Song, Jun-Yi Yin, Fang Geng, Shao-Ping Nie
Summary: The structures of two water-extracted pectic polysaccharides from Fructus aurantii were investigated, and their effects on emulsifying stability were evaluated. Both FWP-60 (extracted by cold water and 60% ethanol precipitation) and FHWP-50 (extracted by hot water and 50% ethanol precipitation) were highly methyl-esterified pectins composed of homogalacturonan (HG) and highly branched rhamnogalacturonan I (RG-I) regions. FWP-60 exhibited better emulsion stability compared to FHWP-50.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Agriculture, Multidisciplinary
Xinping Chang, Jinqiu Wang, Putri Widyanti Harlina, Fang Geng
Summary: In this study, the N-glycosylated protein profiles of cattle-yak longissimus thoracis (CYLT) and yak longissimus thoracis (YLT) were compared using quantitative proteomics techniques. Differential N-glycosylated proteins (DGPs) were screened from the quantified N-glycoproteins, indicating the key role of N-glycosylation levels in the differences between CYLT and YLT. The findings highlight the importance of N-glycosylation in regulating extracellular matrix organization and lysosomal activity.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Acoustics
Haolong Ye, Beibei Wang, Di Xiao, Hanmei Li, Di Wu, Jinqiu Wang, Lei Cheng, Fang Geng
Summary: In this study, a stable aqueous solution of paprika oleoresin (PO) was created, with its solubility increasing rapidly in alkaline aqueous solution. By adding chicken egg yolk low-density lipoprotein (LDL) combined with ultrasonic treatment, the stability of the LDL-PO solution was improved, leading to improved color of various food products and potential health benefits.
ULTRASONICS SONOCHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Ding-Tao Wu, Wen Deng, Jie Li, Jin-Lei Geng, Yi-Chen Hu, Liang Zou, Yi Liu, Hong-Yan Liu, Ren-You Gan
Summary: Fruit thinning is a common practice used to improve the quality and yield of kiwifruits. However, the potential applications of thinned young kiwifruits and their bioactive compounds are still limited in the food and functional food industry.
Article
Biochemistry & Molecular Biology
Ruo-Gu Xiong, Si-Xia Wu, Jin Cheng, Adila Saimaiti, Qing Liu, Ao Shang, Dan-Dan Zhou, Si-Yu Huang, Ren-You Gan, Hua-Bin Li
Summary: This paper explores the production of two novel kombucha beverages with bamboo leaf or mulberry leaf, and compares the effects of fermentation with or without leaf residues on the antioxidant properties of kombucha. The results show that both types of kombucha have high antioxidant capacities, while kombucha fermented with bamboo leaf residues significantly enhances its antioxidant capabilities, total phenolic content, concentrations of some compounds, and sensory acceptability. Fermentation with leaf residues has no significant effect on mulberry leaf kombucha.
Article
Chemistry, Applied
Qiaoyan Wang, Changyu Zhou, Qiang Xia, Daodong Pan, Lihui Du, Jun He, Yangying Sun, Fang Geng, Jinxuan Cao
Summary: The effect of pH treatments on the coacervation mechanism of carrageenan and fibrinogen hydrolysates was investigated. Hydrogels derived from the hydrolysis of alcalase showed the best properties at pH 7.0. These hydrogels had the highest gel strength, best viscoelasticity, and smaller pore sizes. They also showed strong antioxidant capacity and improved preservation times in meat samples.
FOOD HYDROCOLLOIDS
(2024)