Squalene epoxidase promotes colorectal cancer cell proliferation through accumulating calcitriol and activating CYP24A1‐mediated MAPK signaling
出版年份 2021 全文链接
标题
Squalene epoxidase promotes colorectal cancer cell proliferation through accumulating calcitriol and activating CYP24A1‐mediated MAPK signaling
作者
关键词
-
出版物
Cancer Communications
Volume 41, Issue 8, Pages 726-746
出版商
Wiley
发表日期
2021-07-16
DOI
10.1002/cac2.12187
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相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Cancer statistics, 2020
- (2020) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Cholesterol metabolism: New functions and therapeutic approaches in cancer
- (2020) Huanji Xu et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Sterol synthesis pathway inhibition as a target for cancer treatment
- (2020) Sara Feltrin et al. CANCER LETTERS
- Reduction of squalene epoxidase by cholesterol accumulation accelerates colorectal cancer progression and metastasis.
- (2020) Soo Young Jun et al. GASTROENTEROLOGY
- A newly discovered role of metabolic enzyme PCK1 as a protein kinase to promote cancer lipogenesis
- (2020) Hongfei Jiang et al. Cancer Communications
- A Novel Long Non‐Coding RNA lnc030 Maintains Breast Cancer Stem Cell Stemness by Stabilizing SQLE mRNA and Increasing Cholesterol Synthesis
- (2020) Yilu Qin et al. Advanced Science
- Cancer statistics, 2019
- (2019) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Structure and inhibition mechanism of the catalytic domain of human squalene epoxidase
- (2019) Anil K. Padyana et al. Nature Communications
- Squalene epoxidase promotes the proliferation and metastasis of lung squamous cell carcinoma cells though extracellular signal-regulated kinase signaling
- (2019) Hong Ge et al. Thoracic Cancer
- Context Matters - Consensus Molecular Subtypes of Colorectal Cancer as Biomarkers for Clinical Trials
- (2019) E Fontana et al. ANNALS OF ONCOLOGY
- Cholesterol transport through the peroxisome-ER membrane contacts tethered by PI(4,5)P2 and extended synaptotagmins
- (2019) Jian Xiao et al. Science China-Life Sciences
- Biomarker-guided therapy for colorectal cancer: strength in complexity
- (2019) Anita Sveen et al. Nature Reviews Clinical Oncology
- Regulation of glucose and lipid metabolism in health and disease
- (2019) Ligong Chen et al. Science China-Life Sciences
- Greasing the Wheels of the Cancer Machine: The Role of Lipid Metabolism in Cancer
- (2019) Marteinn Thor Snaebjornsson et al. Cell Metabolism
- Squalene epoxidase as a promising metabolic target in cancer treatment
- (2018) Gabriella Cirmena et al. CANCER LETTERS
- Consensus molecular subtypes of colorectal cancer are recapitulated in in vitro and in vivo models
- (2018) Janneke F. Linnekamp et al. CELL DEATH AND DIFFERENTIATION
- Cancer Metabolism: Current Understanding and Therapies
- (2018) Jessica L. Counihan et al. CHEMICAL REVIEWS
- The cancer-associated microprotein CASIMO1 controls cell proliferation and interacts with squalene epoxidase modulating lipid droplet formation
- (2018) Maria Polycarpou-Schwarz et al. ONCOGENE
- Squalene epoxidase drives NAFLD-induced hepatocellular carcinoma and is a pharmaceutical target
- (2018) Dabin Liu et al. Science Translational Medicine
- Progress and potential in organoid research
- (2018) Giuliana Rossi et al. NATURE REVIEWS GENETICS
- Challenges behind proving efficacy of adjuvant chemotherapy after preoperative chemoradiation for rectal cancer
- (2017) Carlos Carvalho et al. LANCET ONCOLOGY
- Cholesterol Metabolism and Prostate Cancer Lethality
- (2016) K. H. Stopsack et al. CANCER RESEARCH
- Modeling Development and Disease with Organoids
- (2016) Hans Clevers CELL
- The Emerging Hallmarks of Cancer Metabolism
- (2016) Natalya N. Pavlova et al. Cell Metabolism
- Potentiating the antitumour response of CD8+ T cells by modulating cholesterol metabolism
- (2016) Wei Yang et al. NATURE
- Chemoprevention of hereditary colon cancers: time for new strategies
- (2016) Luigi Ricciardiello et al. Nature Reviews Gastroenterology & Hepatology
- Vitamin D: Metabolism, Molecular Mechanism of Action, and Pleiotropic Effects
- (2016) Sylvia Christakos et al. PHYSIOLOGICAL REVIEWS
- Fundamentals of cancer metabolism
- (2016) R. J. DeBerardinis et al. Science Advances
- Squalene epoxidase is a bona fide oncogene by amplification with clinical relevance in breast cancer
- (2016) David N. Brown et al. Scientific Reports
- Restoration of the anti-proliferative and anti-migratory effects of 1,25-dihydroxyvitamin D by silibinin in vitamin D-resistant colon cancer cells
- (2015) Vandanajay Bhatia et al. CANCER LETTERS
- Impact of CYP24A1 overexpression on growth of colorectal tumour xenografts in mice fed with vitamin D and soy
- (2015) Julia Höbaus et al. INTERNATIONAL JOURNAL OF CANCER
- The consensus molecular subtypes of colorectal cancer
- (2015) Justin Guinney et al. NATURE MEDICINE
- Dysregulated metabolism contributes to oncogenesis
- (2015) Matthew D. Hirschey et al. SEMINARS IN CANCER BIOLOGY
- The general amino acid control pathway regulates mTOR and autophagy during serum/glutamine starvation
- (2014) Rui Chen et al. JOURNAL OF CELL BIOLOGY
- Critical role of neutral cholesteryl ester hydrolase 1 in cholesteryl ester hydrolysis in murine macrophages
- (2014) Kent Sakai et al. JOURNAL OF LIPID RESEARCH
- The E3 Ubiquitin Ligase MARCH6 Degrades Squalene Monooxygenase and Affects 3-Hydroxy-3-Methyl-Glutaryl Coenzyme A Reductase and the Cholesterol Synthesis Pathway
- (2014) N. Zelcer et al. MOLECULAR AND CELLULAR BIOLOGY
- Vitamin D3 insufficiency and colorectal cancer
- (2013) Michelino Di Rosa et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Increased copy-number and not DNA hypomethylation causes overexpression of the candidate proto-oncogene CYP24A1 in colorectal cancer
- (2013) Julia Höbaus et al. INTERNATIONAL JOURNAL OF CANCER
- Calcium Channels and Pumps in Cancer: Changes and Consequences
- (2012) Gregory R. Monteith et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dietary cholesterol intake and cancer
- (2011) J. Hu et al. ANNALS OF ONCOLOGY
- 25-Hydroxyvitamin D-24-hydroxylase (CYP24A1): Its important role in the degradation of vitamin D
- (2011) Glenville Jones et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Coordination of Triacylglycerol and Cholesterol Homeostasis by DHR96 and the Drosophila LipA Homolog magro
- (2011) Matthew H. Sieber et al. Cell Metabolism
- The Critical Role of Neutral Cholesterol Ester Hydrolase 1 in Cholesterol Removal From Human Macrophages
- (2010) Masaki Igarashi et al. CIRCULATION RESEARCH
- The Candidate Oncogene CYP24A1: A Potential Biomarker for Colorectal Tumorigenesis
- (2009) Henrik C. Horváth et al. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
- Identification of Neutral Cholesterol Ester Hydrolase, a Key Enzyme Removing Cholesterol from Macrophages
- (2008) Hiroaki Okazaki et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitogen-Activated Protein (MAP) Kinase/MAP Kinase Phosphatase Regulation: Roles in Cell Growth, Death, and Cancer
- (2008) T. Boutros et al. PHARMACOLOGICAL REVIEWS
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