The Specific NLRP3 Antagonist IFM-514 Decreases Fibrosis and Inflammation in Experimental Murine Non-Alcoholic Steatohepatitis
出版年份 2021 全文链接
标题
The Specific NLRP3 Antagonist IFM-514 Decreases Fibrosis and Inflammation in Experimental Murine Non-Alcoholic Steatohepatitis
作者
关键词
-
出版物
Frontiers in Molecular Biosciences
Volume 8, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2021-08-26
DOI
10.3389/fmolb.2021.715765
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Combination of CCl4 with alcoholic and metabolic injuries mimics human liver fibrosis
- (2019) Maximilian Joseph Brol et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming
- (2018) Anette Christ et al. CELL
- Targeting the NLRP3 inflammasome in inflammatory diseases
- (2018) Matthew S. J. Mangan et al. NATURE REVIEWS DRUG DISCOVERY
- Beneficial effects of lifestyle intervention in non-obese patients with non-alcoholic fatty liver disease
- (2018) Vincent Wai-Sun Wong et al. JOURNAL OF HEPATOLOGY
- Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders
- (2017) Hua Jiang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice
- (2017) Auvro R. Mridha et al. JOURNAL OF HEPATOLOGY
- Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease
- (2017) Paul M Ridker et al. NEW ENGLAND JOURNAL OF MEDICINE
- Statins improve NASH via inhibition of RhoA and Ras
- (2016) Robert Schierwagen et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Interleukin-1 receptor associated kinase inhibitors: Potential therapeutic agents for inflammatory- and immune-related disorders
- (2015) Malkeet Singh Bahia et al. CELLULAR SIGNALLING
- Liver Fibrosis, but No Other Histologic Features, Is Associated With Long-term Outcomes of Patients With Nonalcoholic Fatty Liver Disease
- (2015) Paul Angulo et al. GASTROENTEROLOGY
- Nonalcoholic Fatty Liver Disease
- (2015) Mary E. Rinella JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Progression of non-alcoholic steatosis to steatohepatitis and fibrosis parallels cumulative accumulation of danger signals that promote inflammation and liver tumors in a high fat–cholesterol–sugar diet model in mice
- (2015) Michal Ganz et al. Journal of Translational Medicine
- Inflammasome activation and function in liver disease
- (2015) Gyongyi Szabo et al. Nature Reviews Gastroenterology & Hepatology
- Genetic background in nonalcoholic fatty liver disease: A comprehensive review
- (2015) Fabio Salvatore Macaluso WORLD JOURNAL OF GASTROENTEROLOGY
- Seven weeks of Western diet in apolipoprotein-E-deficient mice induce metabolic syndrome and non-alcoholic steatohepatitis with liver fibrosis
- (2015) Robert Schierwagen et al. Scientific Reports
- Expression of NALPs in adipose and the fibrotic progression of non-alcoholic fatty liver disease in obese subjects
- (2014) Rohini Mehta et al. BMC GASTROENTEROLOGY
- Angiotensin-II type 1 receptor-mediated Janus kinase 2 activation induces liver fibrosis
- (2014) Michaela Granzow et al. HEPATOLOGY
- Regulation of Lipogenic Gene Expression by Lysine-specific Histone Demethylase-1 (LSD1)
- (2014) Arian Abdulla et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitochondrial NLRP3 Protein Induces Reactive Oxygen Species to Promote Smad Protein Signaling and Fibrosis Independent from the Inflammasome
- (2014) Nathan A. Bracey et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- NLRP3 inflammasome activation is required for fibrosis development in NAFLD
- (2014) Alexander Wree et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice
- (2013) Alexander Wree et al. HEPATOLOGY
- Hepatic cholesterol crystals and crown-like structures distinguish NASH from simple steatosis
- (2013) George N. Ioannou et al. JOURNAL OF LIPID RESEARCH
- Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity
- (2012) Jorge Henao-Mejia et al. NATURE
- Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases
- (2012) Charles A. Dinarello et al. NATURE REVIEWS DRUG DISCOVERY
- The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
- (2011) Bolormaa Vandanmagsar et al. NATURE MEDICINE
- Inflammasome is a central player in the induction of obesity and insulin resistance
- (2011) R. Stienstra et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Inflammasomes
- (2010) Kate Schroder et al. CELL
- Prevalence of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis Among a Largely Middle-Aged Population Utilizing Ultrasound and Liver Biopsy: A Prospective Study
- (2010) Christopher D. Williams et al. GASTROENTEROLOGY
- Specific Contribution of Methionine and Choline in Nutritional Nonalcoholic Steatohepatitis
- (2010) Francisco Caballero et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
- (2010) Peter Duewell et al. NATURE
- Hematopoietic Cell-Specific Deletion of Toll-like Receptor 4 Ameliorates Hepatic and Adipose Tissue Insulin Resistance in High-Fat-Fed Mice
- (2009) Maziyar Saberi et al. Cell Metabolism
- Vascular and inflammatory stresses mediate atherosclerosis via RAGE and its ligands in apoE–/– mice
- (2008) Evis Harja et al. JOURNAL OF CLINICAL INVESTIGATION
- Animal models of NASH: Getting both pathology and metabolic context right
- (2008) Claire Z Larter et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now