Microglia contributes to plaque growth by cell death due to uptake of amyloid β in the brain of Alzheimer's disease mouse model

TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques

(2016) Yaming Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lysosomal proteins in cell death and autophagy

(2015) Michaela Mrschtik et al.   FEBS Journal

GFAP and vimentin deficiency alters gene expression in astrocytes and microglia in wild-type mice and changes the transcriptional response of reactive glia in mouse model for Alzheimer's disease

(2015) Willem Kamphuis et al.   GLIA

Two-Photon Absorbing Dyes with Minimal Autofluorescence in Tissue Imaging: Application to in Vivo Imaging of Amyloid-β Plaques with a Negligible Background Signal

(2015) Dokyoung Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Statins induce insulin-degrading enzyme secretion from astrocytes via an autophagy-based unconventional secretory pathway

(2015) Sung Min Son et al.   Molecular Neurodegeneration

Aβ seeds resist inactivation by formaldehyde

(2014) Sarah K. Fritschi et al.   ACTA NEUROPATHOLOGICA

Impairment of in vivo calcium signaling in amyloid plaque-associated microglia

(2014) Bianca Brawek et al.   ACTA NEUROPATHOLOGICA

Autophagy in microglia degrades extracellular β-amyloid fibrils and regulates the NLRP3 inflammasome

(2014) Mi-Hyang Cho et al.   Autophagy

Highly potent soluble amyloid-β seeds in human Alzheimer brain but not cerebrospinal fluid

(2014) Sarah K. Fritschi et al.   BRAIN

IL-4-Induced Selective Clearance of Oligomeric  -Amyloid Peptide1-42 by Rat Primary Type 2 Microglia

(2014) E. Shimizu et al.   JOURNAL OF IMMUNOLOGY

Migration of neutrophils targeting amyloid plaques in Alzheimer's disease mouse model

(2014) Sung Hoon Baik et al.   NEUROBIOLOGY OF AGING

Activated Scavenger Receptor A Promotes Glial Internalization of Aβ

(2014) He Zhang et al.   PLoS One

In vivo imaging reveals sigmoidal growth kinetic of β-amyloid plaques

(2014) Steffen Burgold et al.   Acta Neuropathologica Communications

Clustering of plaques contributes to plaque growth in a mouse model of Alzheimer’s disease

(2013) Joanna F. McCarter et al.   ACTA NEUROPATHOLOGICA

Microglia actions in Alzheimer’s disease

(2013) Stefan Prokop et al.   ACTA NEUROPATHOLOGICA

Transcranial amelioration of inflammation and cell death after brain injury

(2013) Theodore L. Roth et al.   NATURE

Functional Impairment of Microglia Coincides with Beta-Amyloid Deposition in Mice with Alzheimer-Like Pathology

(2013) Grietje Krabbe et al.   PLoS One

Ubiquitous Amyloids

(2012) Wojciech Pulawski et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Differential cell proliferation in the cortex of the appsweps1de9 alzheimer's disease mouse model

(2012) Willem Kamphuis et al.   GLIA

Efficient isolation of live microglia with preserved phenotypes from adult mouse brain

(2012) Maria Nikodemova et al.   Journal of Neuroinflammation

NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

(2012) Michael T. Heneka et al.   NATURE

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

(2012) Thorlakur Jonsson et al.   NEW ENGLAND JOURNAL OF MEDICINE

TREM2 Variants in Alzheimer's Disease

(2012) Rita Guerreiro et al.   NEW ENGLAND JOURNAL OF MEDICINE

Soluble A  Seeds Are Potent Inducers of Cerebral  -Amyloid Deposition

(2011) F. Langer et al.   JOURNAL OF NEUROSCIENCE

Aβ-induced formation of autophagosomes is mediated by RAGE-CaMKKβ-AMPK signaling

(2011) Sung Min Son et al.   NEUROBIOLOGY OF AGING

Multicolor time-stamp reveals the dynamics and toxicity of amyloid deposition

(2011) Carlo Condello et al.   Scientific Reports

In vivo multiphoton imaging reveals gradual growth of newborn amyloid plaques over weeks

(2010) Steffen Burgold et al.   ACTA NEUROPATHOLOGICA

Regulation of apoptosis-associated lysosomal membrane permeabilization

(2010) Ann-Charlotte Johansson et al.   APOPTOSIS

Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits

(2010) Dun-Sheng Yang et al.   BRAIN

CX3CR1 in Microglia Regulates Brain Amyloid Deposition through Selective Protofibrillar Amyloid-  Phagocytosis

(2010) Z. Liu et al.   JOURNAL OF NEUROSCIENCE

Alzheimer's Disease

(2010) Henry W. Querfurth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Biology of Amyloid: Structure, Function, and Regulation

(2010) Jason Greenwald et al.   STRUCTURE

Microglia Mediate the Clearance of Soluble A  through Fluid Phase Macropinocytosis

(2009) S. Mandrekar et al.   JOURNAL OF NEUROSCIENCE

Amyloid seeds formed by cellular uptake, concentration, and aggregation of the amyloid-beta peptide

(2009) X. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuro-inflammation induced by lipopolysaccharide causes cognitive impairment through enhancement of beta-amyloid generation

(2008) Jae Lee et al.   Journal of Neuroinflammation

Dynamics of the Microglial/Amyloid Interaction Indicate a Role in Plaque Maintenance

(2008) T. Bolmont et al.   JOURNAL OF NEUROSCIENCE

Rapid appearance and local toxicity of amyloid-β plaques in a mouse model of Alzheimer’s disease

(2008) Melanie Meyer-Luehmann et al.   NATURE