Giardia duodenalis Induces Proinflammatory Cytokine Production in Mouse Macrophages via TLR9-Mediated p38 and ERK Signaling Pathways

Giardiavirus: an update

(2021) Francisco Alejandro Lagunas-Rangel et al.   PARASITOLOGY RESEARCH

Extracellular vesicles secreted by Giardia duodenalis regulate host cell innate immunity via TLR2 and NLRP3 inflammasome signaling pathways

(2021) Panpan Zhao et al.   PLoS Neglected Tropical Diseases

Evolving epidemiology of reported giardiasis cases in the United States, 1995–2016

(2020) Cushla M Coffey et al.   CLINICAL INFECTIOUS DISEASES

Giardia lamblia Decreases NF-κB p65RelA Protein Levels and Modulates LPS-Induced Pro-Inflammatory Response in Macrophages

(2020) Clarissa Perez Faria et al.   Scientific Reports

A Novel MicroRNA From the Translated Region of the Giardiavirus rdrp Gene Governs Virus Copy Number in Giardia duodenalis

(2020) Pengtao Gong et al.   Frontiers in Microbiology

Efficient oral vaccination by bioengineering virus-like particles with protozoan surface proteins

(2019) Marianela C. Serradell et al.   Nature Communications

Diminished HIV Infection of Target CD4+ T Cells in a Toll-Like Receptor 4 Stimulated in vitro Model

(2019) Ross Cromarty et al.   Frontiers in Immunology

Signaling Crosstalk Mechanisms That May Fine-Tune Pathogen-Responsive NFκB

(2019) Adewunmi Adelaja et al.   Frontiers in Immunology

MAP kinase phosphatase-1, a gatekeeper of the acute innate immune response

(2019) Sean G. Kirk et al.   LIFE SCIENCES

Requirement of Rab21 in LPS-induced TLR4 signaling and pro-inflammatory responses in macrophages and monocytes

(2018) Ping Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Autophagy downstream of endosomal Toll-like receptor signaling in macrophages is a key mechanism for resistance to Leishmania major infection

(2017) Luis H. Franco et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RhoB induces the production of proinflammatory cytokines in TLR-triggered macrophages

(2017) Shuyuan Liu et al.   MOLECULAR IMMUNOLOGY

The Intersection of Immune Responses, Microbiota, and Pathogenesis in Giardiasis

(2017) Marc Y. Fink et al.   TRENDS IN PARASITOLOGY

Human innate responses and adjuvant activity of TLR ligands in vivo in mice reconstituted with a human immune system

(2017) Liang Cheng et al.   VACCINE

The single cyclic nucleotide-specific phosphodiesterase of the intestinal parasite Giardia lamblia represents a potential drug target

(2017) Stefan Kunz et al.   PLoS Neglected Tropical Diseases

TLR2−/− Mice Display Decreased Severity of Giardiasis via Enhanced Proinflammatory Cytokines Production Dependent on AKT Signal Pathway

(2017) Xin Li et al.   Frontiers in Immunology

An up-date on Giardia and giardiasis

(2016) Elin Einarsson et al.   CURRENT OPINION IN MICROBIOLOGY

Cross talk between Leishmania donovani CpG DNA and Toll-like receptor 9: An immunoinformatics approach

(2015) Chhedi Lal Gupta et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

ADP-Ribosylation Factor 3 Mediates Cytidine-Phosphate-Guanosine Oligodeoxynucleotide-Induced Responses by Regulating Toll-Like Receptor 9 Trafficking

(2015) Jing-Yiing Wu et al.   Journal of Innate Immunity

Macrophages expressing arginase 1 and nitric oxide synthase 2 accumulate in the small intestine during Giardia lamblia infection

(2015) Jenny Maloney et al.   MICROBES AND INFECTION

The Role of Toll-Like Receptor 9 in Chronic Stress-Induced Apoptosis in Macrophage

(2015) Yanxiao Xiang et al.   PLoS One

Giardia duodenalis Surface Cysteine Proteases Induce Cleavage of the Intestinal Epithelial Cytoskeletal Protein Villin via Myosin Light Chain Kinase

(2015) Amol Bhargava et al.   PLoS One

Mechanisms and pathways of innate immune activation and regulation in health and cancer

(2015) Jun Cui et al.   Human Vaccines & Immunotherapeutics

Beyond dsRNA: Toll-like receptor 3 signalling in RNA-induced immune responses

(2014) Megumi Tatematsu et al.   BIOCHEMICAL JOURNAL

Unmethylated CpG motifs in the L. donovani DNA regulate TLR9-dependent delay of programmed cell death in macrophages

(2014) Sushmita Das et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Giardia lambliabinding immunoglobulin protein triggers maturation of dendritic cells via activation of TLR4-MyD88-p38 and ERK1/2 MAPKs

(2014) H.-Y. Lee et al.   PARASITE IMMUNOLOGY

Leishmania aethiopica Field Isolates Bearing an Endosymbiontic dsRNA Virus Induce Pro-inflammatory Cytokine Response

(2014) Haroun Zangger et al.   PLoS Neglected Tropical Diseases

Leishmaniaexpressed lipophosphoglycan interacts with Toll-like receptor (TLR)-2 to decrease TLR-9 expression and reduce anti-leishmanial responses

(2013) S. Srivastava et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Giardia duodenalisAssemblage-Specific Induction of Apoptosis and Tight Junction Disruption in Human Intestinal Epithelial Cells: Effects of Mixed Infections

(2013) Wan Hon Koh et al.   JOURNAL OF PARASITOLOGY

The Villain Team-Up or howTrichomonas vaginalisand bacterial vaginosis alter innate immunity in concert

(2013) Raina N Fichorova et al.   SEXUALLY TRANSMITTED INFECTIONS

Persistent gut barrier damage and commensal bacterial influx following eradication of Giardia infection in mice

(2013) Tzu-Ling Chen et al.   Gut Pathogens

Excretory-secretory products of Giardia lamblia induce interleukin-8 production in human colonic cells via activation of p38, ERK1/2, NF-κB and AP-1

(2012) H.-Y. LEE et al.   PARASITE IMMUNOLOGY

Intestinal growth and pathology of Giardia duodenalis assemblage subtype AI, AII, B and E in the gerbil model

(2012) E. BÉNÉRÉ et al.   PARASITOLOGY

Endobiont Viruses Sensed by the Human Host – Beyond Conventional Antiparasitic Therapy

(2012) Raina N. Fichorova et al.   PLoS One

Granulin Is a Soluble Cofactor for Toll-like Receptor 9 Signaling

(2011) Boyoun Park et al.   IMMUNITY

Leishmania RNA Virus Controls the Severity of Mucocutaneous Leishmaniasis

(2011) A. Ives et al.   SCIENCE

Phagocytosis of Giardia lamblia trophozoites by cytokine-activated macrophages

(2010) M. BELOSEVIC et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Functional role of Akt in macrophage-mediated innate immunity

(2010) Yong Gyu Lee   Frontiers in Bioscience-Landmark

In vitro activation of murine peritoneal macrophages by recombinant YopJ: Production of nitric oxide, proinflammatory cytokines and chemokines

(2010) Ajit Sodhi et al.   IMMUNOBIOLOGY

Pathogen recognition in the innate immune response

(2009) Himanshu Kumar et al.   BIOCHEMICAL JOURNAL

IFN-gamma, IL-5, IL-6 and IgE in patients infected with Giardia intestinalis.

(2009) Joanna Matowicka-Karna et al.   FOLIA HISTOCHEMICA ET CYTOBIOLOGICA

The roles of TLRs, RLRs and NLRs in pathogen recognition

(2009) T. Kawai et al.   INTERNATIONAL IMMUNOLOGY

Requirement for DNA CpG Content in TLR9-Dependent Dendritic Cell Activation Induced by DNA-Containing Immune Complexes

(2009) K. Yasuda et al.   JOURNAL OF IMMUNOLOGY

Pulsatile Stimulation Determines Timing and Specificity of NF- B-Dependent Transcription

(2009) L. Ashall et al.   SCIENCE

TLR9 as a key receptor for the recognition of DNA☆

(2008) Y KUMAGAI et al.   ADVANCED DRUG DELIVERY REVIEWS

Sensing of Viral Infection and Activation of Innate Immunity by Toll-Like Receptor 3

(2008) E. Vercammen et al.   CLINICAL MICROBIOLOGY REVIEWS

Phosphoinositide 3-Kinase-Dependent Inhibition of Dendritic Cell Interleukin-12 Production by Giardia lamblia

(2008) J. D. Kamda et al.   INFECTION AND IMMUNITY

Fecundity of Cryptosporidium parvum is correlated with intracellular levels of the viral symbiont CPV

(2007) M.C. Jenkins et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY