In-vitro and in-vivo characterization of CRANAD-2 for multi-spectral optoacoustic tomography and fluorescence imaging of amyloid-beta deposits in Alzheimer mice

Multi-scale optoacoustic molecular imaging of brain diseases

(2021) Daniel Razansky et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

In vitro Characterization of the Regional Binding Distribution of Amyloid PET Tracer Florbetaben and the Glia Tracers Deprenyl and PK11195 in Autopsy Alzheimer’s Brain Tissue

(2021) Ruiqing Ni et al.   JOURNAL OF ALZHEIMERS DISEASE

Aggregation-Induced Absorption Enhancement for Deep Near-Infrared II Photoacoustic Imaging of Brain Gliomas In Vivo

(2019) Yajing Liu et al.   Advanced Science

fMRI Reveals Mitigation of Cerebrovascular Dysfunction by Bradykinin Receptors 1 and 2 Inhibitor Noscapine in a Mouse Model of Cerebral Amyloidosis

(2019) Ruiqing Ni et al.   Frontiers in Aging Neuroscience

Spatial and Spectral Mapping and Decomposition of Neural Dynamics and Organization of the Mouse Brain with Multispectral Optoacoustic Tomography

(2019) Ivan Olefir et al.   Cell Reports

Rapid one-step 18F-radiolabeling of biomolecules in aqueous media by organophosphine fluoride acceptors

(2019) Huawei Hong et al.   Nature Communications

Automated registration of magnetic resonance imaging and optoacoustic tomography data for experimental studies

(2019) Wuwei Ren et al.   Neurophotonics

Photoacoustic imaging as a tool to probe the tumour microenvironment

(2019) Emma Brown et al.   Disease Models & Mechanisms

NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease

(2018) Clifford R. Jack et al.   Alzheimers & Dementia

Translational opportunities for amyloid-targeting fluorophores

(2018) Kevin J. Cao et al.   CHEMICAL COMMUNICATIONS

Imaging tau and amyloid-β proteinopathies in Alzheimer disease and other conditions

(2018) Victor L. Villemagne et al.   Nature Reviews Neurology

Performance of optoacoustic and fluorescence imaging in detecting deep-seated fluorescent agents

(2018) Zhenyue Chen et al.   Biomedical Optics Express

Noninvasive detection of acute cerebral hypoxia and subsequent matrix-metalloproteinase activity in a mouse model of cerebral ischemia using multispectral-optoacoustic-tomography

(2018) Ruiqing Ni et al.   Neurophotonics

In vivo Detection of Amyloid Plaques in the Mouse Brain using the Near-Infrared Fluorescence Probe THK-265

(2018) Nobuyuki Okamura et al.   JOURNAL OF ALZHEIMERS DISEASE

Positron Emission Tomography (PET) Ligand Development for Ionotropic Glutamate Receptors: Challenges and Opportunities for Radiotracer Targeting N-Methyl-d-aspartate (NMDA), α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA), and Kainate Receptors

(2018) Hualong Fu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Efficient 3-D Model-Based Reconstruction Scheme for Arbitrary Optoacoustic Acquisition Geometries

(2017) Lu Ding et al.   IEEE TRANSACTIONS ON MEDICAL IMAGING

Pushing the Boundaries of Neuroimaging with Optoacoustics

(2017) Saak V. Ovsepian et al.   NEURON

Hybrid system for in vivo epifluorescence and 4D optoacoustic imaging

(2017) Zhenyue Chen et al.   OPTICS LETTERS

Oxalate-curcumin–based probe for micro- and macroimaging of reactive oxygen species in Alzheimer’s disease

(2017) Jian Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Highly specific noninvasive photoacoustic and positron emission tomography of brain plaque with functionalized croconium dye labeled by a radiotracer

(2017) Yajing Liu et al.   Chemical Science

Extracerebral Tissue Damage in the Intraluminal Filament Mouse Model of Middle Cerebral Artery Occlusion

(2017) Markus Vaas et al.   Frontiers in Neurology

Thioflavin T as an amyloid dye: fibril quantification, optimal concentration and effect on aggregation

(2017) Christine Xue et al.   Royal Society Open Science

A theranostic agent for in vivo near-infrared imaging of β-amyloid species and inhibition of β-amyloid aggregation

(2016) Yinhui Li et al.   BIOMATERIALS

Quantitative assessment of microvasculopathy in arcAβ mice with USPIO-enhanced gradient echo MRI

(2016) Jan Klohs et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

18F-Labeled Benzyldiamine Derivatives as Novel Flexible Probes for Positron Emission Tomography of Cerebral β-Amyloid Plaques

(2016) Zijing Li et al.   JOURNAL OF MEDICINAL CHEMISTRY

The activities of amyloids from a structural perspective

(2016) Roland Riek et al.   NATURE

A practical guide to photoacoustic tomography in the life sciences

(2016) Lihong V Wang et al.   NATURE METHODS

Antibody-based PET imaging of amyloid beta in mouse models of Alzheimer’s disease

(2016) Dag Sehlin et al.   Nature Communications

Functional optoacoustic neuro-tomography for scalable whole-brain monitoring of calcium indicators

(2016) X Luís Deán-Ben et al.   Light-Science & Applications

Florbetaben PET imaging to detect amyloid beta plaques in Alzheimer's disease: Phase 3 study

(2015) Osama Sabri et al.   Alzheimers & Dementia

Astrocytosis precedes amyloid plaque deposition in Alzheimer APPswe transgenic mouse brain: a correlative positron emission tomography and in vitro imaging study

(2015) Elena Rodriguez-Vieitez et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Advances in real-time multispectral optoacoustic imaging and its applications

(2015) Adrian Taruttis et al.   Nature Photonics

A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers

(2015) Samuel I A Cohen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Protective properties of lysozyme on β-amyloid pathology: implications for Alzheimer disease

(2015) Linda Helmfors et al.   NEUROBIOLOGY OF DISEASE

Near-infrared fluorescence molecular imaging of amyloid beta species and monitoring therapy in animal models of Alzheimer’s disease

(2015) Xueli Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers

(2015) Samuel I A Cohen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Phase 3 Trial of Flutemetamol Labeled With Radioactive Fluorine 18 Imaging and Neuritic Plaque Density

(2015) Craig Curtis et al.   JAMA Neurology

Smart Near-Infrared Fluorescence Probes with Donor–Acceptor Structure for in Vivo Detection of β-Amyloid Deposits

(2014) Mengchao Cui et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Longitudinal PET-MRI reveals β-amyloid deposition and rCBF dynamics and connects vascular amyloidosis to quantitative loss of perfusion

(2014) Florian C Maier et al.   NATURE MEDICINE

Amyloid tracers detect multiple binding sites in Alzheimer's disease brain tissue

(2013) R. Ni et al.   BRAIN

Volumetric Real-Time Tracking of Peripheral Human Vasculature With GPU-Accelerated Three-Dimensional Optoacoustic Tomography

(2013) X. Luis Dean-Ben et al.   IEEE TRANSACTIONS ON MEDICAL IMAGING

Longitudinal Assessment of Cerebral  -Amyloid Deposition in Mice Overexpressing Swedish Mutant  -Amyloid Precursor Protein Using 18F-Florbetaben PET

(2013) A. Rominger et al.   JOURNAL OF NUCLEAR MEDICINE

Quantification of the Concentration of Aβ42 Propagons during the Lag Phase by an Amyloid Chain Reaction Assay

(2013) Paolo Arosio et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Design and Synthesis of Curcumin Analogues for in Vivo Fluorescence Imaging and Inhibiting Copper-Induced Cross-Linking of Amyloid Beta Species in Alzheimer’s Disease

(2013) Xueli Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Longitudinal Assessment of Amyloid Pathology in Transgenic ArcAβ Mice Using Multi-Parametric Magnetic Resonance Imaging

(2013) Jan Klohs et al.   PLoS One

Contrast-Enhanced Magnetic Resonance Microangiography Reveals Remodeling of the Cerebral Microvasculature in Transgenic ArcA  Mice

(2012) J. Klohs et al.   JOURNAL OF NEUROSCIENCE

Small-Animal PET Imaging of Amyloid-Beta Plaques with [11C]PiB and Its Multi-Modal Validation in an APP/PS1 Mouse Model of Alzheimer's Disease

(2012) André Manook et al.   PLoS One

Use of Florbetapir-PET for Imaging β-Amyloid Pathology

(2011) Christopher M. Clark   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Volumetric real-time multispectral optoacoustic tomography of biomarkers

(2011) Daniel Razansky et al.   Nature Protocols

Non-Conjugated Small Molecule FRET for Differentiating Monomers from Higher Molecular Weight Amyloid Beta Species

(2011) Chongzhao Ran et al.   PLoS One

Novel Pentameric Thiophene Derivatives forin Vitroandin VivoOptical Imaging of a Plethora of Protein Aggregates in Cerebral Amyloidoses

(2009) Andreas Åslund et al.   ACS Chemical Biology

Design, Synthesis, and Testing of Difluoroboron-Derivatized Curcumins as Near-Infrared Probes for in Vivo Detection of Amyloid-β Deposits

(2009) Chongzhao Ran et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Post-mortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimer's disease

(2008) Milos D. Ikonomovic et al.   BRAIN

Hybrid FMT–CT imaging of amyloid-β plaques in a murine Alzheimer's disease model

(2008) D HYDE et al.   NEUROIMAGE