The role of SHP/REV-ERBα/CYP4A axis in the pathogenesis of alcohol-associated liver disease

Resolving the fibrotic niche of human liver cirrhosis at single-cell level

(2019) P. Ramachandran et al.   NATURE

Loss of PDK4 switches the hepatic NF-κB/TNF pathway from pro-survival to pro-apoptosis

(2018) Jianguo Wu et al.   HEPATOLOGY

Long noncoding RNA H19 interacts with polypyrimidine tract-binding protein 1 to reprogram hepatic lipid homeostasis

(2018) Chune Liu et al.   HEPATOLOGY

MetaboAnalyst 4.0: towards more transparent and integrative metabolomics analysis

(2018) Jasmine Chong et al.   NUCLEIC ACIDS RESEARCH

Ablation of cytochrome P450 omega-hydroxylase 4A14 gene attenuates hepatic steatosis and fibrosis

(2017) Xiaoyan Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

REV-ERBα Activates C/EBP Homologous Protein to Control Small Heterodimer Partner–Mediated Oscillation of Alcoholic Fatty Liver

(2016) Zhihong Yang et al.   AMERICAN JOURNAL OF PATHOLOGY

Alcoholic Liver Disease in Asia, Europe, and North America

(2016) Suthat Liangpunsakul et al.   GASTROENTEROLOGY

Alcoholic hepatitis: Translational approaches to develop targeted therapies

(2016) Pranoti Mandrekar et al.   HEPATOLOGY

Circadian clock control of hepatic lipid metabolism: role of small heterodimer partner (Shp)

(2016) Li Wang et al.   JOURNAL OF INVESTIGATIVE MEDICINE

Alcohol: taking a population perspective

(2016) William Gilmore et al.   Nature Reviews Gastroenterology & Hepatology

Dissociation between diurnal cycles in locomotor activity, feeding behavior and hepatic PERIOD2 expression in chronic alcohol-fed mice

(2015) Peng Zhou et al.   ALCOHOL

Small heterodimer partner/neuronal PAS domain protein 2 axis regulates the oscillation of liver lipid metabolism

(2015) Sang Min Lee et al.   HEPATOLOGY

Arachidonic acid monooxygenase: Genetic and biochemical approaches to physiological/pathophysiological relevance

(2015) Jorge H. Capdevila et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Discrete functions of nuclear receptor Rev-erb  couple metabolism to the clock

(2015) Y. Zhang et al.   SCIENCE

Molecular mechanisms of the microsomal mixed function oxidases and biological and pathological implications

(2015) Arthur I. Cederbaum   Redox Biology

Inhibition of CYP4A Reduces Hepatic Endoplasmic Reticulum Stress and Features of Diabetes in Mice

(2014) Edmond Changkyun Park et al.   GASTROENTEROLOGY

E2F1 is a novel fibrogenic gene that regulates cholestatic liver fibrosis through the Egr-1/SHP/EID1 network

(2014) Yuxia Zhang et al.   HEPATOLOGY

Influence of unrecorded alcohol consumption on liver cirrhosis mortality

(2014) Dirk W Lachenmeier   WORLD JOURNAL OF GASTROENTEROLOGY

Genome-wide transcriptome analysis identifies novel gene signatures implicated in human chronic liver disease

(2013) Rana L. Smalling et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Mouse model of chronic and binge ethanol feeding (the NIAAA model)

(2013) Adeline Bertola et al.   Nature Protocols

Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists

(2012) Laura A. Solt et al.   NATURE

Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β

(2012) Han Cho et al.   NATURE

Innate immunity in alcoholic liver disease

(2011) Bin Gao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The REV-ERBs and RORs: molecular links between circadian rhythms and lipid homeostasis

(2011) Laura A Solt et al.   Future Medicinal Chemistry

Alcoholic Liver Disease: Pathogenesis and New Therapeutic Targets

(2011) Bin Gao et al.   GASTROENTEROLOGY

Regulation of metabolism: the circadian clock dictates the time

(2011) Saurabh Sahar et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Ethanol-Induced Alterations in Fatty Acid-Related Lipids in Serum and Tissues in Mice

(2010) Zhenwen Zhao et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Role of nuclear receptor SHP in metabolism and cancer

(2010) Yuxia Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Diurnal Regulation of MTP and Plasma Triglyceride by CLOCK Is Mediated by SHP

(2010) Xiaoyue Pan et al.   Cell Metabolism

The Role of Lipid Metabolism in the Pathogenesis of Alcoholic and Nonalcoholic Hepatic Steatosis

(2010) Margaret Sozio et al.   SEMINARS IN LIVER DISEASE

Role of oxidative stress in alcohol-induced liver injury

(2009) Arthur I. Cederbaum et al.   ARCHIVES OF TOXICOLOGY

REV-ERBα Participates in Circadian SREBP Signaling and Bile Acid Homeostasis

(2009) Gwendal Le Martelot et al.   PLOS BIOLOGY

Cytochrome P450 omega hydroxylase (CYP4) function in fatty acid metabolism and metabolic diseases

(2008) James P. Hardwick   BIOCHEMICAL PHARMACOLOGY