Japanese Encephalitis Virus NS2B-3 Protein Complex Promotes Cell Apoptosis and Viral Particle Release by Down-Regulating the Expression of AXL

Extracellular Vesicles in the Pathogenesis of Viral Infections in Humans

(2020) Allen Caobi et al.   Viruses-Basel

Host and Viral Proteins Modulating Ebola and Marburg Virus Egress

(2019) Tamsin Gordon et al.   Viruses-Basel

Exosomes mediate Zika virus transmission through SMPD3 neutral Sphingomyelinase in cortical neurons

(2019) Wenshuo Zhou et al.   Emerging Microbes & Infections

TIM-mediated inhibition of HIV-1 release is antagonized by Nef but potentiated by SERINC proteins

(2019) Minghua Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting of the AXL receptor tyrosine kinase by small molecule inhibitor leads to AXL cell surface accumulation by impairing the ubiquitin-dependent receptor degradation

(2019) Markus Lauter et al.   Cell Communication and Signaling

Zika virus circumvents host innate immunity by targeting the adaptor proteins MAVS and MITA

(2019) Wenjiao Li et al.   FASEB JOURNAL

Review of Emerging Japanese Encephalitis Virus: New Aspects and Concepts about Entry into the Brain and Inter-Cellular Spreading

(2019) Filgueira et al.   Pathogens

NS2B/NS3 mutations enhance the infectivity of genotype I Japanese encephalitis virus in amplifying hosts

(2019) Yi-Chin Fan et al.   PLoS Pathogens

Zika NS2B is a crucial factor recruiting NS3 to the ER and activating its protease activity

(2019) Huaipeng Xing et al.   VIRUS RESEARCH

Biochemistry and Molecular Biology of Flaviviruses

(2018) Nicholas J. Barrows et al.   CHEMICAL REVIEWS

Rewiring cellular networks by members of the Flaviviridae family

(2018) Christopher J. Neufeldt et al.   NATURE REVIEWS MICROBIOLOGY

Species-specific disruption of STING-dependent antiviral cellular defenses by the Zika virus NS2B3 protease

(2018) Qiang Ding et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Sertoli cells support high levels of Zika virus replication and persistence

(2018) Anil Kumar et al.   Scientific Reports

Exosomes serve as novel modes of tick-borne flavivirus transmission from arthropod to human cells and facilitates dissemination of viral RNA and proteins to the vertebrate neuronal cells

(2018) Wenshuo Zhou et al.   PLoS Pathogens

AXL promotes Zika virus infection in astrocytes by antagonizing type I interferon signalling

(2018) Jian Chen et al.   Nature Microbiology

The immune response against flaviviruses

(2018) Jose Luis Slon Campos et al.   NATURE IMMUNOLOGY

Axl is not an indispensable factor for Zika virus infection in mice

(2017) Zhao-Yang Wang et al.   JOURNAL OF GENERAL VIROLOGY

AXL-dependent infection of human fetal endothelial cells distinguishes Zika virus from other pathogenic flaviviruses

(2017) Audrey Stéphanie Richard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Apoptosis during Flavivirus Infection

(2017) Toru Okamoto et al.   Viruses-Basel

Innate Immune Evasion Mediated by Flaviviridae Non-Structural Proteins

(2017) Shun Chen et al.   Viruses-Basel

TAM Receptors Are Not Required for Zika Virus Infection in Mice

(2017) Andrew K. Hastings et al.   Cell Reports

Zika virus evades interferon-mediated antiviral response through the co-operation of multiple nonstructural proteins in vitro

(2017) Yaoxing Wu et al.   Cell Discovery

Zika Virus Targets Different Primary Human Placental Cells, Suggesting Two Routes for Vertical Transmission

(2016) Takako Tabata et al.   Cell Host & Microbe

Genetic Ablation of AXL Does Not Protect Human Neural Progenitor Cells and Cerebral Organoids from Zika Virus Infection

(2016) Michael F. Wells et al.   Cell Stem Cell

Exosomes in Viral Disease

(2016) Monique R. Anderson et al.   Neurotherapeutics

Zika virus cell tropism in the developing human brain and inhibition by azithromycin

(2016) Hanna Retallack et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structure of Zika virus NS2B-NS3 protease in complex with a boronate inhibitor

(2016) Jian Lei et al.   SCIENCE

Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics

(2016) George Savidis et al.   Cell Reports

TAM Receptor Signaling in Immune Homeostasis

(2015) Carla V. Rothlin et al.   Annual Review of Immunology

Phosphatidylserine Vesicles Enable Efficient En Bloc Transmission of Enteroviruses

(2015) Ying-Han Chen et al.   CELL

The A66G back mutation in NS2A of JEV SA 14 -14-2 strain contributes to production of NS1′ protein and the secreted NS1′ can be used for diagnostic biomarker for virulent virus infection

(2015) Jingman Wang et al.   INFECTION GENETICS AND EVOLUTION

Biology of Zika Virus Infection in Human Skin Cells

(2015) Rodolphe Hamel et al.   JOURNAL OF VIROLOGY

TIM-family proteins inhibit HIV-1 release

(2014) M. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enveloped Viruses Disable Innate Immune Responses in Dendritic Cells by Direct Activation of TAM Receptors

(2013) Suchita Bhattacharyya et al.   Cell Host & Microbe

Biology of the TAM Receptors

(2013) G. Lemke   Cold Spring Harbor Perspectives in Biology

The TIM and TAM Families of Phosphatidylserine Receptors Mediate Dengue Virus Entry

(2012) Laurent Meertens et al.   Cell Host & Microbe

Efficient Clearance of Early Apoptotic Cells by Human Macrophages Requires M2c Polarization and MerTK Induction

(2012) G. Zizzo et al.   JOURNAL OF IMMUNOLOGY

Innate Immunity Evasion by Dengue Virus

(2012) Juliet Morrison et al.   Viruses-Basel

Dendritic Cell Apoptosis and the Pathogenesis of Dengue

(2012) Sharon Martins et al.   Viruses-Basel

DENV Inhibits Type I IFN Production in Infected Cells by Cleaving Human STING

(2012) Sebastian Aguirre et al.   PLoS Pathogens

Estimated global incidence of Japanese encephalitis:

(2011) Grant Campbell et al.   BULLETIN OF THE WORLD HEALTH ORGANIZATION

The Soluble Serum Protein Gas6 Bridges Virion Envelope Phosphatidylserine to the TAM Receptor Tyrosine Kinase Axl to Mediate Viral Entry

(2011) Kouki Morizono et al.   Cell Host & Microbe

Inhibition of the Type I Interferon Response in Human Dendritic Cells by Dengue Virus Infection Requires a Catalytically Active NS2B3 Complex

(2010) J. R. Rodriguez-Madoz et al.   JOURNAL OF VIROLOGY

Japanese encephalitis virus NS2B-NS3 protease induces caspase 3 activation and mitochondria-mediated apoptosis in human medulloblastoma cells

(2009) Tsuey-Ching Yang et al.   VIRUS RESEARCH