The Pathogenic and Therapeutic Implications of Ceramide Abnormalities in Atopic Dermatitis
出版年份 2021 全文链接
标题
The Pathogenic and Therapeutic Implications of Ceramide Abnormalities in Atopic Dermatitis
作者
关键词
-
出版物
Cells
Volume 10, Issue 9, Pages 2386
出版商
MDPI AG
发表日期
2021-09-13
DOI
10.3390/cells10092386
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Ceramide liposomes for skin barrier recovery: a novel formulation based on natural skin lipids
- (2021) Aneta Vovesná et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Treatment with Synthetic Pseudoceramide Improves Atopic Skin, Switching the Ceramide Profile to a Healthy Skin Phenotype
- (2020) Koichi Ishida et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Comparative profiling and comprehensive quantification of stratum corneum ceramides in humans and mice by LC/MS/MS
- (2020) Momoko Kawana et al. JOURNAL OF LIPID RESEARCH
- Skin of atopic dermatitis patients shows disturbed β-glucocerebrosidase and acid sphingomyelinase activity that relates to changes in stratum corneum lipid composition
- (2020) Daphne E.C. Boer et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- An Investigation of the Skin Barrier Restoring Effects of a Cream and Lotion Containing Ceramides in a Multi-vesicular Emulsion in People with Dry, Eczema-Prone, Skin: The RESTORE Study Phase 1
- (2020) Simon G. Danby et al. Dermatology and Therapy
- Dupilumab reduces inflammation and restores the skin barrier in patients with atopic dermatitis
- (2020) Maria Helena Rohner et al. ALLERGY
- Sphingomyelin Deacylase, the Enzyme Involved in the Pathogenesis of Atopic Dermatitis, Is Identical to the β-Subunit of Acid Ceramidase
- (2020) Yasuhiro Teranishi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Effects of Delgocitinib Ointment 0.5% on the Normal Mouse Skin and Epidermal Tight Junction Proteins in Comparison With Topical Corticosteroids
- (2020) Akiko Anagawa-Nakamura et al. TOXICOLOGIC PATHOLOGY
- IFN-γ Reduces Epidermal Barrier Function by Affecting Fatty Acid Composition of Ceramide in a Mouse Atopic Dermatitis Model
- (2019) Hiroyuki Kanoh et al. Journal of Immunology Research
- PEBBLES study protocol: a randomised controlled trial to prevent atopic dermatitis, food allergy and sensitisation in infants with a family history of allergic disease using a skin barrier improvement strategy
- (2019) Adrian Lowe et al. BMJ Open
- The Cornified Envelope-Bound Ceramide Fraction Is Altered in Patients with Atopic Dermatitis
- (2019) Walter Boiten et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Comparing the effects of proactive treatment with tacrolimus ointment and mometasone furoate on the epidermal barrier structure and ceramide levels of patients with atopic dermatitis
- (2019) Dorothee Dähnhardt et al. JOURNAL OF DERMATOLOGICAL TREATMENT
- Eicosapentaenoic acid ethyl ester ameliorates atopic dermatitis-like symptoms in special diet-fed hairless mice, partly by restoring covalently bound ceramides in the stratum corneum
- (2018) Masanori Fujii et al. EXPERIMENTAL DERMATOLOGY
- Atopic dermatitis
- (2018) Stephan Weidinger et al. Nature Reviews Disease Primers
- ABHD5 stimulates PNPLA1-mediated ω-O-acylceramide biosynthesis essential for a functional skin permeability barrier
- (2018) Benedikt Kien et al. JOURNAL OF LIPID RESEARCH
- Permeability and microstructure of cholesterol-depleted skin lipid membranes and human stratum corneum
- (2018) Michaela Sochorová et al. JOURNAL OF COLLOID AND INTERFACE SCIENCE
- Altered expression of epidermal lipid bio-synthesis enzymes in atopic dermatitis skin is accompanied by changes in stratum corneum lipid composition
- (2017) Mogbekeloluwa Danso et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- As in Atopic Dermatitis, Nonlesional Skin in Allergic Contact Dermatitis Displays Abnormalities in Barrier Function and Ceramide Content
- (2017) Donghye Kim et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- PNPLA1 is a transacylase essential for the generation of the skin barrier lipid ω-O-acylceramide
- (2017) Yusuke Ohno et al. Nature Communications
- Synthesis and degradation pathways, functions, and pathology of ceramides and epidermal acylceramides
- (2016) Akio Kihara PROGRESS IN LIPID RESEARCH
- Dietary deficiencies of unsaturated fatty acids and starch cause atopic dermatitis-like pruritus in hairless mice
- (2015) Masanori Fujii et al. EXPERIMENTAL DERMATOLOGY
- Relationship of ceramide–, and free fatty acid–cholesterol ratios in the stratum corneum with skin barrier function of normal, atopic dermatitis lesional and non-lesional skins
- (2015) Kyung-Mi Joo et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- Essential role of the cytochrome P450 CYP4F22 in the production of acylceramide, the key lipid for skin permeability barrier formation
- (2015) Yusuke Ohno et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Chemistry and Biology of 6-Hydroxyceramide, the Youngest Member of the Human Sphingolipid Family
- (2014) Andrej Kováčik et al. CHEMBIOCHEM
- Causes of epidermal filaggrin reduction and their role in the pathogenesis of atopic dermatitis
- (2014) Jacob P. Thyssen et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- TNF-α and Th2 Cytokines Induce Atopic Dermatitis–Like Features on Epidermal Differentiation Proteins and Stratum Corneum Lipids in Human Skin Equivalents
- (2014) Mogbekeloluwa O. Danso et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- New insights into the epidemiology of childhood atopic dermatitis
- (2013) C. Flohr et al. ALLERGY
- Barrier Repair Therapy in Atopic Dermatitis: An Overview
- (2013) Kam Lun Hon et al. AMERICAN JOURNAL OF CLINICAL DERMATOLOGY
- Formation and functions of the corneocyte lipid envelope (CLE)
- (2013) Peter M. Elias et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- The roles of ABCA12 in epidermal lipid barrier formation and keratinocyte differentiation
- (2013) Masashi Akiyama BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- The importance of the lipoxygenase-hepoxilin pathway in the mammalian epidermal barrier
- (2013) Agustí Muñoz-Garcia et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Combined LC/MS-platform for analysis of all major stratum corneum lipids, and the profiling of skin substitutes
- (2013) Jeroen van Smeden et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- The important role of stratum corneum lipids for the cutaneous barrier function
- (2013) J. van Smeden et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Deficiency of n-6 polyunsaturated fatty acids is mainly responsible for atopic dermatitis-like pruritic skin inflammation in special diet-fed hairless mice
- (2013) Masanori Fujii et al. EXPERIMENTAL DERMATOLOGY
- The importance of free fatty acid chain length for the skin barrier function in atopic eczema patients
- (2013) Jeroen van Smeden et al. EXPERIMENTAL DERMATOLOGY
- Impaired Epidermal Ceramide Synthesis Causes Autosomal Recessive Congenital Ichthyosis and Reveals the Importance of Ceramide Acyl Chain Length
- (2013) Katja-Martina Eckl et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Interferon-γ Decreases Ceramides with Long-Chain Fatty Acids: Possible Involvement in Atopic Dermatitis and Psoriasis
- (2013) Chisato Tawada et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- 1-O-acylceramides are natural components of human and mouse epidermis
- (2013) Mariona Rabionet et al. JOURNAL OF LIPID RESEARCH
- Impaired Epidermal Permeability Barrier in Mice Lacking Elovl1, the Gene Responsible for Very-Long-Chain Fatty Acid Production
- (2013) T. Sassa et al. MOLECULAR AND CELLULAR BIOLOGY
- Application of Glucosylceramide-Based Liposomes Increased the Ceramide Content in a Three-Dimensional Cultured Skin Epidermis
- (2013) Y. Tokudome et al. SKIN PHARMACOLOGY AND PHYSIOLOGY
- Th1 cytokines accentuate but Th2 cytokines attenuate ceramide production in the stratum corneum of human epidermal equivalents: An implication for the disrupted barrier mechanism in atopic dermatitis
- (2012) Eri Sawada et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- The Human Skin Barrier Is Organized as Stacked Bilayers of Fully Extended Ceramides with Cholesterol Molecules Associated with the Ceramide Sphingoid Moiety
- (2012) Ichiro Iwai et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Aloxe3 Knockout Mice Reveal a Function of Epidermal Lipoxygenase-3 as Hepoxilin Synthase and Its Pivotal Role in Barrier Formation
- (2012) Peter Krieg et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Increase in short-chain ceramides correlates with an altered lipid organization and decreased barrier function in atopic eczema patients
- (2012) Michelle Janssens et al. JOURNAL OF LIPID RESEARCH
- PNPLA1 mutations cause autosomal recessive congenital ichthyosis in golden retriever dogs and humans
- (2012) Anaïs Grall et al. NATURE GENETICS
- Recessive Mutations in ELOVL4 Cause Ichthyosis, Intellectual Disability, and Spastic Quadriplegia
- (2011) Mohammed A. Aldahmesh et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Profiling and Characterizing Skin Ceramides Using Reversed-Phase Liquid Chromatography–Quadrupole Time-of-Flight Mass Spectrometry
- (2011) Ruben t’Kindt et al. ANALYTICAL CHEMISTRY
- Distinct barrier integrity phenotypes in filaggrin-related atopic eczema following sequential tape stripping and lipid profiling
- (2011) Irena Angelova-Fischer et al. EXPERIMENTAL DERMATOLOGY
- Loss of ceramide synthase 3 causes lethal skin barrier disruption
- (2011) Richard Jennemann et al. HUMAN MOLECULAR GENETICS
- Lipoxygenases Mediate the Effect of Essential Fatty Acid in Skin Barrier Formation
- (2011) Yuxiang Zheng et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Lamellar Lipid Organization and Ceramide Composition in the Stratum Corneum of Patients with Atopic Eczema
- (2011) Michelle Janssens et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Decrease of Ceramides with Very Long–Chain Fatty Acids and Downregulation of Elongases in a Murine Atopic Dermatitis Model
- (2011) Yang-Hui Park et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Stratum corneum lipids, skin barrier function and filaggrin mutations in patients with atopic eczema
- (2010) J. M. Jungersted et al. ALLERGY
- Changes in the Ceramide Profile of Atopic Dermatitis Patients
- (2010) Junko Ishikawa et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Ceramide biosynthesis in keratinocyte and its role in skin function
- (2009) Yukiko Mizutani et al. BIOCHIMIE
- Topical calcineurin inhibitors compromise stratum corneum integrity, epidermal permeability and antimicrobial barrier function
- (2009) Minjeong Kim et al. EXPERIMENTAL DERMATOLOGY
- Different effects of pimecrolimus and betamethasone on the skin barrier in patients with atopic dermatitis
- (2009) Jens-Michael Jensen et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- A possible mechanism underlying the ceramide deficiency in atopic dermatitis: Expression of a deacylase enzyme that cleaves the N-acyl linkage of sphingomyelin and glucosylceramide
- (2009) Genji Imokawa JOURNAL OF DERMATOLOGICAL SCIENCE
- Safety studies of pseudo-ceramide SLE66: Acute and short-term toxicity
- (2008) Osamu Morita et al. FOOD AND CHEMICAL TOXICOLOGY
- On the effects of topical synthetic pseudoceramides: Comparison of possible keratinocyte toxicities provoked by the pseudoceramides, PC104 and BIO391, and natural ceramides
- (2008) Yoshikazu Uchida et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- Omega-O-acylceramide, a lipid essential for mammalian survival
- (2008) Yoshikazu Uchida et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- Characterization of overall ceramide species in humanstratum corneum
- (2008) Yoshinori Masukawa et al. JOURNAL OF LIPID RESEARCH
- IL-4 Suppresses the Recovery of Cutaneous Permeability Barrier Functions In Vivo
- (2007) Rieko Kurahashi et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
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