High-throughput screening for amyloid-β binding natural small-molecules based on the combinational use of biolayer interferometry and UHPLC−DAD-Q/TOF-MS/MS

Subcutaneous daratumumab and hyaluronidase-fihj in newly diagnosed or relapsed/refractory multiple myeloma

(2021) Larysa Sanchez et al.   Therapeutic Advances in Hematology

Fast Screening of Biomembrane-Permeable Compounds in Herbal Medicines Using Bubble-Generating Magnetic Liposomes Coupled with LC–MS

(2021) Xiaoting Gu et al.   MOLECULES

Lipids and Alzheimer’s Disease

(2020) Yu-Chia Kao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Highly Flexible Ligand Docking: Benchmarking of the DockThor Program on the LEADS-PEP Protein–Peptide Data Set

(2020) Karina B. Santos et al.   Journal of Chemical Information and Modeling

Improved protein structure prediction using predicted interresidue orientations

(2020) Jianyi Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipids Nutrients in Parkinson and Alzheimer’s Diseases: Cell Death and Cytoprotection

(2020) Thomas Nury et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Roles of the PI3K/AKT/mTOR signalling pathways in neurodegenerative diseases and tumours

(2020) Fei Xu et al.   Cell and Bioscience

Rational design of a conformation-specific antibody for the quantification of Aβ oligomers

(2020) Francesco A. Aprile et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lychee seed polyphenol inhibits Aβ-induced activation of NLRP3 inflammasome via the LRP1/AMPK mediated autophagy induction

(2020) Wen-Qiao Qiu et al.   BIOMEDICINE & PHARMACOTHERAPY

Lychee seed polyphenol protects the blood–brain barrier through inhibiting Aβ(25–35)‐induced NLRP3 inflammasome activation via the AMPK / mTOR / ULK1‐mediated autophagy in bEnd .3 cells and APP / PS1 mice

(2020) Rui Xiong et al.   PHYTOTHERAPY RESEARCH

Integrated Network Pharmacology Analysis and Pharmacological Evaluation to Explore the Active Components and Mechanism of Abelmoschus manihot (L.) Medik. on Renal Fibrosis

(2020) Lifei Gu et al.   Drug Design Development and Therapy

The Function of Transthyretin Complexes with Metallothionein in Alzheimer’s Disease

(2020) Natalia Zaręba et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

NMR-based Lavado cocoa chemical characterization and comparison with fermented cocoa varieties: Insights on cocoa’s anti-amyloidogenic activity

(2020) Carlotta Ciaramelli et al.   FOOD CHEMISTRY

UHPLC-QTOF/MS-based metabolomics investigation for the protective mechanism of Danshen in Alzheimer’s disease cell model induced by Aβ1–42

(2019) Mingyong Zhang et al.   Metabolomics

The New Application of UHPLC-DAD-TOF/MS in Identification of Inhibitors on β-Amyloid Fibrillation From Scutellaria baicalensis

(2019) Lu Yu et al.   Frontiers in Pharmacology

Structure-Based Peptide Inhibitor Design of Amyloid-β Aggregation

(2019) Jinxia Lu et al.   Frontiers in Molecular Neuroscience

Dexmedetomidine inhibits astrocyte pyroptosis and subsequently protects the brain in in vitro and in vivo models of sepsis

(2019) Yi-Bing Sun et al.   Cell Death & Disease

Phenolic Compounds from Five Ericaceae Species Leaves and Their Related Bioavailability and Health Benefits

(2019) Bianca Eugenia Ștefănescu et al.   MOLECULES

Fibroblast growth factor 21 ameliorates neurodegeneration in rat and cellular models of Alzheimer’s disease

(2019) Song Chen et al.   Redox Biology

Oleocanthal-Rich Extra-Virgin Olive Oil Restores the Blood–Brain Barrier Function through NLRP3 Inflammasome Inhibition Simultaneously with Autophagy Induction in TgSwDI Mice

(2019) Sweilem B. Al Rihani et al.   ACS Chemical Neuroscience

Classic Prescription, Kai-Xin-San, Ameliorates Alzheimer’s Disease as an Effective Multitarget Treatment: From Neurotransmitter to Protein Signaling Pathway

(2019) Sirui Guo et al.   Oxidative Medicine and Cellular Longevity

A Snapshot on the Current Status of Alzheimer’s Disease, Treatment Perspectives, in-Vitro and in-Vivo Research Studies and Future Opportunities

(2019) Gizem Tezel et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Cell Chromatography-Based Screening of the Active Components in Buyang Huanwu Decoction Promoting Axonal Regeneration

(2019) Xiangli Yan et al.   Biomed Research International

Extracellular vesicles derived from human Wharton’s jelly mesenchymal stem cells protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers

(2019) Victor Bodart-Santos et al.   Stem Cell Research & Therapy

Amyloid β-protein oligomers promote the uptake of tau fibril seeds potentiating intracellular tau aggregation

(2019) Woo Shik Shin et al.   Alzheimers Research & Therapy

Advance directives as a tool to respect patients’ values and preferences: discussion on the case of Alzheimer’s disease

(2018) Corinna Porteri   BMC Medical Ethics

Stimulation of SIRT1 Attenuates the Level of Oxidative Stress in the Brains of APP/PS1 Double Transgenic Mice and in Primary Neurons Exposed to Oligomers of the Amyloid-β Peptide

(2018) Yang-Ting Dong et al.   JOURNAL OF ALZHEIMERS DISEASE

The Aβ protofibril selective antibody mAb158 prevents accumulation of Aβ in astrocytes and rescues neurons from Aβ-induced cell death

(2018) Sofia Söllvander et al.   Journal of Neuroinflammation

What is the impact of regulatory guidance and expiry of drug patents on dementia drug prescriptions in England? A trend analysis in the Clinical Practice Research Datalink

(2018) Venexia M. Walker et al.   Alzheimers Research & Therapy

Ferulic Acid Inhibits the Transition of Amyloid-β42 Monomers to Oligomers but Accelerates the Transition from Oligomers to Fibrils

(2018) Lili Cui et al.   JOURNAL OF ALZHEIMERS DISEASE

Correlation between Quality and Geographical Origins of Poria cocos Revealed by Qualitative Fingerprint Profiling and Quantitative Determination of Triterpenoid Acids

(2018) Li-Xia Zhu et al.   MOLECULES

Ocular Manifestations of Alzheimer’s and Other Neurodegenerative Diseases: The Prospect of the Eye as a Tool for the Early Diagnosis of Alzheimer’s Disease

(2018) Pade Colligris et al.   Journal of Ophthalmology

Rapid Screening of Active Components with an Osteoclastic Inhibitory Effect in Herba epimedii Using Quantitative Pattern–Activity Relationships Based on Joint-Action Models

(2017) Xiao-Yan Yuan et al.   MOLECULES

Visualization of neuritic plaques in Alzheimer’s disease by polarization-sensitive optical coherence microscopy

(2017) Bernhard Baumann et al.   Scientific Reports

Kai-Xin-San, a standardized traditional Chinese medicine formula, up-regulates the expressions of synaptic proteins on hippocampus of chronic mild stress induced depressive rats and primary cultured rat hippocampal neuron

(2016) Yue Zhu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Development of an Innovative in Vitro Potency Assay for Anti-Botulinum Antitoxins

(2016) Osnat Rosen et al.   Toxins

Optimization of the All-D Peptide D3 for Aβ Oligomer Elimination

(2016) Antonia Nicole Klein et al.   PLoS One

The standardized Lycium chinense fruit extract protects against Alzheimer׳s disease in 3xTg-AD mice

(2015) Minsook Ye et al.   JOURNAL OF ETHNOPHARMACOLOGY

Bioactive Marine Drugs and Marine Biomaterials for Brain Diseases

(2014) Clara Grosso et al.   Marine Drugs

Preclinical and clinical issues in Alzheimer's disease drug research and development

(2014) Cesare Mancuso et al.   Frontiers in Pharmacology

The effect of Chinese Jinzhida recipe on the hippocampus in a rat model of diabetes-associated cognitive decline

(2013) Xiao-Hui Chang et al.   BMC Complementary and Alternative Medicine

Baicalein reduces β-amyloid and promotes nonamyloidogenic amyloid precursor protein processing in an Alzheimer's disease transgenic mouse model

(2013) She-Qing Zhang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Immobilized magnetic beads based multi-target affinity selection coupled with high performance liquid chromatography–mass spectrometry for screening anti-diabetic compounds from a Chinese medicine “Tang-Zhi-Qing”

(2013) Yi Tao et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Modeling Alzheimer’s disease: from past to future

(2013) Claudia Saraceno et al.   Frontiers in Pharmacology

Quercetin and rutin exhibit antiamyloidogenic and fibril-disaggregating effects in vitro and potent antioxidant activity in APPswe cells

(2011) Karim Jiménez-Aliaga et al.   LIFE SCIENCES