Rational design of a conformation-specific antibody for the quantification of Aβ oligomers
出版年份 2020 全文链接
标题
Rational design of a conformation-specific antibody for the quantification of Aβ oligomers
作者
关键词
-
出版物
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 117, Issue 24, Pages 13509-13518
出版商
Proceedings of the National Academy of Sciences
发表日期
2020-06-04
DOI
10.1073/pnas.1919464117
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Dynamics of oligomer populations formed during the aggregation of Alzheimer’s Aβ42 peptide
- (2020) Thomas C. T. Michaels et al. Nature Chemistry
- Target Engagement in an Alzheimer Trial: Crenezumab Lowers Aβ Oligomers in CSF
- (2019) Ting Yang et al. ANNALS OF NEUROLOGY
- Stabilization and characterization of cytotoxic Aβ40 oligomers isolated from an aggregation reaction in the presence of zinc ions
- (2018) Benedetta Mannini et al. ACS Chemical Neuroscience
- NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease
- (2018) Clifford R. Jack et al. Alzheimers & Dementia
- SAR by kinetics for drug discovery in protein misfolding diseases
- (2018) Sean Chia et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers
- (2017) Giuliana Fusco et al. SCIENCE
- Selective targeting of primary and secondary nucleation pathways in Aβ42 aggregation using a rational antibody scanning method
- (2017) Francesco A. Aprile et al. Science Advances
- The Cellular Phase of Alzheimer’s Disease
- (2016) Bart De Strooper et al. CELL
- Atomic Resolution Structure of Monomorphic Aβ42 Amyloid Fibrils
- (2016) Michael T. Colvin et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Complement and microglia mediate early synapse loss in Alzheimer mouse models
- (2016) S. Hong et al. SCIENCE
- Antibody-based PET imaging of amyloid beta in mouse models of Alzheimer’s disease
- (2016) Dag Sehlin et al. Nature Communications
- Nanoscale studies link amyloid maturity with polyglutamine diseases onset
- (2016) F. S. Ruggeri et al. Scientific Reports
- An anticancer drug suppresses the primary nucleation reaction that initiates the production of the toxic A 42 aggregates linked with Alzheimers disease
- (2016) J. Habchi et al. Science Advances
- Microfluidic Diffusion Analysis of the Sizes and Interactions of Proteins under Native Solution Conditions
- (2015) Paolo Arosio et al. ACS Nano
- Rational design of antibodies targeting specific epitopes within intrinsically disordered proteins
- (2015) Pietro Sormanni et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Conformational targeting of intracellular Aβ oligomers demonstrates their pathological oligomerization inside the endoplasmic reticulum
- (2014) Giovanni Meli et al. Nature Communications
- Neuroinflammation and Neuronal Loss Precede Aβ Plaque Deposition in the hAPP-J20 Mouse Model of Alzheimer’s Disease
- (2013) Amanda L. Wright et al. PLoS One
- Proliferation of amyloid- 42 aggregates occurs through a secondary nucleation mechanism
- (2013) S. I. A. Cohen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Direct Observation of the Interconversion of Normal and Toxic Forms of α-Synuclein
- (2012) Nunilo Cremades et al. CELL
- Utility of an improved model of amyloid-beta (Aβ1-42) toxicity in Caenorhabditis elegans for drug screening for Alzheimer’s disease
- (2012) Gawain McColl et al. Molecular Neurodegeneration
- The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes
- (2012) Iryna Benilova et al. NATURE NEUROSCIENCE
- Beyond natural antibodies: the power of in vitro display technologies
- (2011) Andrew R M Bradbury et al. NATURE BIOTECHNOLOGY
- Alzheimer's Disease: The Challenge of the Second Century
- (2011) D. M. Holtzman et al. Science Translational Medicine
- An Analytical Solution to the Kinetics of Breakable Filament Assembly
- (2009) T. P. J. Knowles et al. SCIENCE
- Protein therapeutics: a summary and pharmacological classification
- (2007) Benjamin Leader et al. NATURE REVIEWS DRUG DISCOVERY
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