标题
Deregulation of HLA-I in cancer and its central importance for immunotherapy
作者
关键词
-
出版物
Journal for ImmunoTherapy of Cancer
Volume 9, Issue 8, Pages e002899
出版商
BMJ
发表日期
2021-08-06
DOI
10.1136/jitc-2021-002899
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- HLA class I loss in colorectal cancer: implications for immune escape and immunotherapy
- (2021) Per Anderson et al. Cellular & Molecular Immunology
- Co-expression of HLA-I loci improved prognostication in HER2+ breast cancers
- (2020) Julia Y. Tsang et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- A Unique Regulation Region in the 3′ UTR of HLA-G with a Promising Potential
- (2020) Adi Reches et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Identification of biomarkers of immune checkpoint blockade efficacy in recurrent or refractory solid tumor malignancies
- (2020) Richard K. Yang et al. Oncotarget
- HLA-corrected tumor mutation burden and homologous recombination deficiency for the prediction of response to PD-(L)1 blockade in advanced non-small-cell lung cancer patients
- (2020) J.H. Shim et al. ANNALS OF ONCOLOGY
- Differential prognostic impact of CD8+ T cells based on human leucocyte antigen I and PD-L1 expression in microsatellite-unstable gastric cancer
- (2020) Yoonjin Kwak et al. BRITISH JOURNAL OF CANCER
- The NKG2A - HLA-E axis as a novel checkpoint in the tumor microenvironment
- (2020) Linda Borst et al. CLINICAL CANCER RESEARCH
- The prevalence of HLA LOH across 10 cancer types in Chinese patients.
- (2020) Jian'An Huang et al. JOURNAL OF CLINICAL ONCOLOGY
- The role of cancer-derived microRNAs in cancer immune escape
- (2020) Ming Yi et al. Journal of Hematology & Oncology
- Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I
- (2020) Keisuke Yamamoto et al. NATURE
- The tumor microenvironment as a metabolic barrier to effector T cells and immunotherapy
- (2020) Aaron R Lim et al. eLife
- The immune-checkpoint HLA-G/ILT4 is involved in the regulation of VEGF expression in clear cell renal cell carcinoma
- (2020) Marcela García et al. BMC CANCER
- Expression of classical human leukocyte antigen class I antigens, HLA‐E and HLA‐G, is adversely prognostic in pancreatic cancer patients
- (2020) Nobuyoshi Hiraoka et al. CANCER SCIENCE
- HLA-G: A New Immune Checkpoint in Cancer?
- (2020) Daniëlle Krijgsman et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- HLA-G Neo-Expression on Tumors
- (2020) Maria Loustau et al. Frontiers in Immunology
- Restoration of MHC-I on Tumor Cells by Fhit Transfection Promotes Immune Rejection and Acts as an Individualized Immunotherapeutic Vaccine
- (2020) María Pulido et al. Cancers
- MHC Class I Downregulation in Cancer: Underlying Mechanisms and Potential Targets for Cancer Immunotherapy
- (2020) Annelisa M. Cornel et al. Cancers
- Multi-Omics Characterization of the 4T1 Murine Mammary Gland Tumor Model
- (2020) Barbara Schrörs et al. Frontiers in Oncology
- HLA Genotyping in Synovial Sarcoma: Identifying HLA-A*02 and Its Association with Clinical Outcome
- (2020) Evan Rosenbaum et al. CLINICAL CANCER RESEARCH
- Turning up the heat on non-immunoreactive tumours: opportunities for clinical development
- (2020) María Ochoa de Olza et al. LANCET ONCOLOGY
- Cancer-associated fibroblasts downregulate type I interferon receptor to stimulate intratumoral stromagenesis
- (2020) Christina Cho et al. ONCOGENE
- Uncoupling interferon signaling and antigen presentation to overcome immunotherapy resistance due to JAK1 loss in melanoma
- (2020) Anusha Kalbasi et al. Science Translational Medicine
- HLA-G and HLA-F protein isoform expression in breast cancer patients receiving neoadjuvant treatment
- (2020) Franziska M. Wuerfel et al. Scientific Reports
- Expression of human leukocyte antigen class I and β2‐microglobulin in colorectal cancer and its prognostic impact
- (2020) Hee Young Na et al. CANCER SCIENCE
- Tumor Mutational Burden as a Predictor of Immunotherapy Response: Is More Always Better?
- (2020) John H. Strickler et al. CLINICAL CANCER RESEARCH
- Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma
- (2019) Moshe Sade-Feldman et al. CELL
- Class I transactivator, NLRC5: a central player in the MHC class I pathway and cancer immune surveillance
- (2019) Saptha Vijayan et al. IMMUNOGENETICS
- Confirmation that somatic mutations of beta‐2 microglobulin correlate with a lack of recurrence in a subset of stage II mismatch repair deficient colorectal cancers from the QUASAR trial
- (2019) P. Barrow et al. HISTOPATHOLOGY
- Oncolytic virotherapy enhances the efficacy of a cancer vaccine by modulating the tumor microenvironment
- (2019) Iris Koske et al. INTERNATIONAL JOURNAL OF CANCER
- Targeting Cancer Stem Cells: A Strategy for Effective Eradication of Cancer
- (2019) Masahiro Shibata et al. Cancers
- Elevated neoantigen levels in tumors with somatic mutations in the HLA-A, HLA-B, HLA-C and B2M genes
- (2019) Andrea Castro et al. BMC Medical Genomics
- Tumor-intrinsic PIK3CA represses tumor immunogenicity in a model of pancreatic cancer
- (2019) Nithya Sivaram et al. JOURNAL OF CLINICAL INVESTIGATION
- Prognostic value of the association between MHC class I downregulation and PD-L1 upregulation in head and neck squamous cell carcinoma patients
- (2019) Shin Hye Yoo et al. Scientific Reports
- The Emerging Roles of Human Leukocyte Antigen-F in Immune Modulation and Viral Infection
- (2019) Aifen Lin et al. Frontiers in Immunology
- Metabolic stress in cancer cells induces immune escape through a PI3K-dependent blockade of IFNγ receptor signaling
- (2019) Koen A. Marijt et al. Journal for ImmunoTherapy of Cancer
- Type I interferon suppresses tumor growth through activating the STAT3-granzyme B pathway in tumor-infiltrating cytotoxic T lymphocytes
- (2019) Chunwan Lu et al. Journal for ImmunoTherapy of Cancer
- Phosphoinositide 3-kinase signaling can modulate MHC class I and II expression
- (2019) Sanjay Chandrasekaran et al. MOLECULAR CANCER RESEARCH
- CD8+PD-1–ILT2+ T Cells Are an Intratumoral Cytotoxic Population Selectively Inhibited by the Immune-Checkpoint HLA-G
- (2019) Clement Dumont et al. Cancer Immunology Research
- Intratumoral immunotherapy with TLR7/8 agonist MEDI9197 modulates the tumor microenvironment leading to enhanced activity when combined with other immunotherapies
- (2019) Stefanie R. Mullins et al. Journal for ImmunoTherapy of Cancer
- LBA71Phase II multicenter open label study of pembrolizumab and entinostat in adult patients with metastatic uveal melanoma (PEMDAC study)
- (2019) H Jespersen et al. ANNALS OF ONCOLOGY
- Clinicopathologic significance of human leukocyte antigen class I expression in patients with stage II and III gastric cancer
- (2019) Yujun Park et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Cancer immune escape: MHC expression in primary tumours versus metastases
- (2019) Federico Garrido et al. IMMUNOLOGY
- Engineering Newcastle disease virus as oncolytic vector for intratumoral delivery of immune checkpoint inhibitors and immunocytokines
- (2019) Gayathri Vijayakumar et al. JOURNAL OF VIROLOGY
- MHC class I dysfunction of glioma stem cells escapes from CTL-mediated immune response via activation of Wnt/β-catenin signaling pathway
- (2019) Wei Yang et al. ONCOGENE
- Tumor Mutational Burden as a Predictive Biomarker for Response to Immune Checkpoint Inhibitors: A Review of Current Evidence
- (2019) Samuel J. Klempner et al. ONCOLOGIST
- Mobilizing unconventional T cells
- (2019) Tom H. M. Ottenhoff et al. SCIENCE
- An inhalable nanoparticulate STING agonist synergizes with radiotherapy to confer long-term control of lung metastases
- (2019) Yang Liu et al. Nature Communications
- Improved Anti-Tumour Adaptive Immunity Can Overcome the Melanoma Immunosuppressive Tumour Microenvironment
- (2019) Nana Dang et al. Cancers
- Extracellular pH modulating injectable gel for enhancing immune checkpoint inhibitor therapy
- (2019) Hyung-seung Jin et al. JOURNAL OF CONTROLLED RELEASE
- Reduction of MHC-I expression limits T-lymphocyte-mediated killing of Cancer-initiating cells
- (2018) Brian J. Morrison et al. BMC CANCER
- The RNA-binding Protein MEX3B Mediates Resistance to Cancer Immunotherapy by Downregulating HLA-A Expression
- (2018) Lu Huang et al. CLINICAL CANCER RESEARCH
- Natural killer cell education in human health and disease
- (2018) Jeanette E Boudreau et al. CURRENT OPINION IN IMMUNOLOGY
- microRNA 125a Regulates MHC-I Expression on Esophageal Adenocarcinoma Cells, Associated With Suppression of Anti-tumor Immune Response and Poor Outcomes of Patients
- (2018) Luigi Mari et al. GASTROENTEROLOGY
- MHC proteins confer differential sensitivity to CTLA-4 and PD-1 blockade in untreated metastatic melanoma
- (2018) Scott J. Rodig et al. Science Translational Medicine
- Exploring the links between cancer and placenta development
- (2018) Vincenzo Costanzo et al. Open Biology
- Complex pattern of immune evasion in MSI colorectal cancer
- (2018) Mine Ozcan et al. OncoImmunology
- Efficacy and safety of entinostat (ENT) and pembrolizumab (PEMBRO) in patients with non-small cell lung cancer (NSCLC) previously treated with anti-PD-(L)1 therapy.
- (2018) Leena Gandhi et al. JOURNAL OF CLINICAL ONCOLOGY
- Efficacy and safety of entinostat (ENT) and pembrolizumab (PEMBRO) in patients with melanoma progressing on or after a PD-1/L1 blocking antibody.
- (2018) Sanjiv S. Agarwala et al. JOURNAL OF CLINICAL ONCOLOGY
- Enhanced anti-tumor efficacy of checkpoint inhibitors in combination with the histone deacetylase inhibitor Belinostat in a murine hepatocellular carcinoma model
- (2018) Diana Llopiz et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Anti-NKG2A mAb Is a Checkpoint Inhibitor that Promotes Anti-tumor Immunity by Unleashing Both T and NK Cells
- (2018) Pascale André et al. CELL
- High HLA-F Expression Is a Poor Prognosis Factor in Patients with Nasopharyngeal Carcinoma
- (2018) Bo Wu et al. Analytical Cellular Pathology
- Human Leukocyte Antigen F Presents Peptides and Regulates Immunity through Interactions with NK Cell Receptors
- (2017) Charles L. Dulberger et al. IMMUNITY
- The regulatory network behind MHC class I expression
- (2017) Marlieke L.M. Jongsma et al. MOLECULAR IMMUNOLOGY
- Cancer stem cells revisited
- (2017) Eduard Batlle et al. NATURE MEDICINE
- Epigenetic therapy activates type I interferon signaling in murine ovarian cancer to reduce immunosuppression and tumor burden
- (2017) Meredith L. Stone et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade
- (2017) Dung T. Le et al. SCIENCE
- Patient HLA class I genotype influences cancer response to checkpoint blockade immunotherapy
- (2017) Diego Chowell et al. SCIENCE
- Evaluation of ascitic soluble human leukocyte antigen-G for distinguishing malignant ascites from benign ascites
- (2017) Juan Sun et al. TUMOR BIOLOGY
- Resistance to checkpoint blockade therapy through inactivation of antigen presentation
- (2017) Moshe Sade-Feldman et al. Nature Communications
- Impaired HLA Class I Antigen Processing and Presentation as a Mechanism of Acquired Resistance to Immune Checkpoint Inhibitors in Lung Cancer
- (2017) Scott Gettinger et al. Cancer Discovery
- HLA class I loss and PD-L1 expression in lung cancer: impact on T-cell infiltration and immune escape
- (2017) Francisco Perea et al. Oncotarget
- Importance of the plasma soluble HLA-G levels for prognostic stratification with traditional prognosticators in colorectal cancer
- (2017) Jing-Bo Li et al. Oncotarget
- Predictive value of different proportion of lesion HLA-G expression in colorectal cancer
- (2017) Rui-Li Zhang et al. Oncotarget
- HDAC inhibition potentiates immunotherapy in triple negative breast cancer
- (2017) Manuela Terranova-Barberio et al. Oncotarget
- Epi-drugs in combination with immunotherapy: a new avenue to improve anticancer efficacy
- (2017) Roberta Mazzone et al. Clinical Epigenetics
- The prognostic impact of programmed cell death ligand 1 and human leukocyte antigen class I in pancreatic cancer
- (2017) Daisuke Imai et al. Cancer Medicine
- Intratumor heterogeneity of immune checkpoints in primary renal cell cancer: Focus on HLA-G/ILT2/ILT4
- (2017) Nathalie Rouas-Freiss et al. OncoImmunology
- Loss of tapasin in human lung and colon cancer cells and escape from tumor-associated antigen-specific CTL recognition
- (2017) Yosuke Shionoya et al. OncoImmunology
- Hypoxia and hypoxia-inducible factor (HIF) downregulate antigen-presenting MHC class I molecules limiting tumor cell recognition by T cells
- (2017) Shalini Sethumadhavan et al. PLoS One
- Expression of PD-L1 and HLA Class I in Esophageal Squamous Cell Carcinoma: Prognostic Factors for Patient Outcome
- (2016) Shuhei Ito et al. ANNALS OF SURGICAL ONCOLOGY
- Suppression of Type I IFN Signaling in Tumors Mediates Resistance to Anti-PD-1 Treatment That Can Be Overcome by Radiotherapy
- (2016) Xiaohong Wang et al. CANCER RESEARCH
- Hide-and-seek: the interplay between cancer stem cells and the immune system
- (2016) Mohammad Sultan et al. CARCINOGENESIS
- Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy
- (2016) Jianjun Gao et al. CELL
- Role of microRNAs on HLA-G expression in human tumors
- (2016) Barbara Seliger HUMAN IMMUNOLOGY
- HNRNPR Regulates the Expression of Classical and Nonclassical MHC Class I Proteins
- (2016) Adi Reches et al. JOURNAL OF IMMUNOLOGY
- Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma
- (2016) Jesse M. Zaretsky et al. NEW ENGLAND JOURNAL OF MEDICINE
- NLRC5/MHC class I transactivator is a target for immune evasion in cancer
- (2016) Sayuri Yoshihama et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Proteomic screening identifies calreticulin as a miR-27a direct target repressing MHC class I cell surface exposure in colorectal cancer
- (2016) T Colangelo et al. Cell Death & Disease
- Primary Resistance to PD-1 Blockade Mediated by JAK1/2 Mutations
- (2016) Daniel Sanghoon Shin et al. Cancer Discovery
- Lack of interferon-γ receptor results in a microenvironment favorable for intestinal tumorigenesis
- (2016) Caibo Zhang et al. Oncotarget
- Identification of novel microRNAs regulating HLA-G expression and investigating their clinical relevance in renal cell carcinoma
- (2016) Simon Jasinski-Bergner et al. Oncotarget
- Hypoxia inducible factor-1 mediates the expression of the immune checkpoint HLA-G in glioma cells through hypoxia response element located in exon 2
- (2016) Layale Yaghi et al. Oncotarget
- Kinase Regulation of Human MHC Class I Molecule Expression on Cancer Cells
- (2016) E. J. Brea et al. Cancer Immunology Research
- Characteristics of HLA-E Restricted T-Cell Responses and Their Role in Infectious Diseases
- (2016) Simone A. Joosten et al. Journal of Immunology Research
- Targetless T cells in cancer immunotherapy
- (2016) Per thor Straten et al. Journal for ImmunoTherapy of Cancer
- Classical and non-classical HLA class I aberrations in primary cervical squamous- and adenocarcinomas and paired lymph node metastases
- (2016) Debbie M. Ferns et al. Journal for ImmunoTherapy of Cancer
- Neutralization of Tumor Acidity Improves Antitumor Responses to Immunotherapy
- (2015) Shari Pilon-Thomas et al. CANCER RESEARCH
- Predictive value of HLA-G and HLA-E in the prognosis of colorectal cancer patients
- (2015) Zhang-Yan Guo et al. CELLULAR IMMUNOLOGY
- The BRAF and MEK Inhibitors Dabrafenib and Trametinib: Effects on Immune Function and in Combination with Immunomodulatory Antibodies Targeting PD-1, PD-L1, and CTLA-4
- (2015) L. Liu et al. CLINICAL CANCER RESEARCH
- RAS/MAPK Activation Is Associated with Reduced Tumor-Infiltrating Lymphocytes in Triple-Negative Breast Cancer: Therapeutic Cooperation Between MEK and PD-1/PD-L1 Immune Checkpoint Inhibitors
- (2015) S. Loi et al. CLINICAL CANCER RESEARCH
- Suppression of antigen presentation by IL-10
- (2015) Sharad K Mittal et al. CURRENT OPINION IN IMMUNOLOGY
- Monoclonal antibodies to HLA-E bind epitopes carried by unfolded β2m-free heavy chains
- (2015) Elisa Tremante et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Epigenetic regulation of differentialHLA-Aallelic expression levels
- (2015) Veron Ramsuran et al. HUMAN MOLECULAR GENETICS
- Tumor border sharpness correlates with HLA-G expression in low-grade gliomas
- (2015) Yinyan Wang et al. JOURNAL OF NEUROIMMUNOLOGY
- TGF-β and EGF induced HLA-I downregulation is associated with epithelial-mesenchymal transition (EMT) through upregulation of snail in prostate cancer cells
- (2015) Xiao-Hui Chen et al. MOLECULAR IMMUNOLOGY
- Comprehensive analysis of cancer-associated somatic mutations in class I HLA genes
- (2015) Sachet A Shukla et al. NATURE BIOTECHNOLOGY
- Clinical implication of human leukocyte antigen (HLA)-F expression in breast cancer
- (2015) Aya Harada et al. PATHOLOGY INTERNATIONAL
- STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity
- (2015) Olivier Demaria et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The HLA-G cycle provides for both NK tolerance and immunity at the maternal–fetal interface
- (2015) Tamara Tilburgs et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade
- (2015) Juan Fu et al. Science Translational Medicine
- Down-expression of miR-152 lead to impaired anti-tumor effect of NK via upregulation of HLA-G
- (2015) Xiaokun Bian et al. TUMOR BIOLOGY
- Molecular Backgrounds of ERAP1 Downregulation in Cervical Carcinoma
- (2015) Akash M. Mehta et al. Analytical Cellular Pathology
- A non-proteolytic role for ubiquitin in deadenylation of MHC-I mRNA by the RNA-binding E3-ligase MEX-3C
- (2015) Florencia Cano et al. Nature Communications
- Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity
- (2015) Leticia Corrales et al. Cell Reports
- BRAFV600E Co-opts a Conserved MHC Class I Internalization Pathway to Diminish Antigen Presentation and CD8+ T-cell Recognition of Melanoma
- (2015) S. D. Bradley et al. Cancer Immunology Research
- Alterations of immune response of non-small cell lung cancer with Azacytidine
- (2015) John Wrangle et al. Oncotarget
- Prognostic impact of programmed cell death 1 ligand 1 expression in human leukocyte antigen class I-positive hepatocellular carcinoma after curative hepatectomy
- (2014) Yuichiroh Umemoto et al. JOURNAL OF GASTROENTEROLOGY
- Spatial and temporal diversity in genomic instability processes defines lung cancer evolution
- (2014) E. C. de Bruin et al. SCIENCE
- HLA Class Ib Molecules and Immune Cells in Pregnancy and Preeclampsia
- (2014) Snezana Djurisic et al. Frontiers in Immunology
- EGFR-mediated tumor immunoescape
- (2014) Fernando Concha-Benavente et al. OncoImmunology
- DNA Methyltransferases: A Novel Target for Prevention and Therapy
- (2014) Dharmalingam Subramaniam et al. Frontiers in Oncology
- Immune escape of cancer cells with beta2-microglobulin loss over the course of metastatic melanoma
- (2013) Ana B. del Campo et al. INTERNATIONAL JOURNAL OF CANCER
- RNA Sequencing Identifies Multiple Fusion Transcripts, Differentially Expressed Genes, and Reduced Expression of Immune Function Genes inBRAF(V600E) Mutant vsBRAFWild-Type Papillary Thyroid Carcinoma
- (2013) Robert C. Smallridge et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- The MAPK Pathway Is a Predominant Regulator of HLA-A Expression in Esophageal and Gastric Cancer
- (2013) K. Mimura et al. JOURNAL OF IMMUNOLOGY
- Cancer-Initiating Cells from Colorectal Cancer Patients Escape from T Cell-Mediated Immunosurveillance In Vitro through Membrane-Bound IL-4
- (2013) A. Volonte et al. JOURNAL OF IMMUNOLOGY
- The relationship between KRAS gene mutations and HLA class I antigen downregulation in the metastasis of non-small cell lung cancer
- (2013) Xiao-Peng He et al. JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
- Microenvironmental regulation of tumor progression and metastasis
- (2013) Daniela F Quail et al. NATURE MEDICINE
- Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position
- (2013) Jason D Buenrostro et al. NATURE METHODS
- Vemurafenib enhances MHC induction inBRAFV600Ehomozygous melanoma cells
- (2013) Bishu Sapkota et al. OncoImmunology
- Modulation of Microenvironment Acidity Reverses Anergy in Human and Murine Tumor-Infiltrating T Lymphocytes
- (2012) A. Calcinotto et al. CANCER RESEARCH
- Multimeric structures of HLA-G isoforms function through differential binding to LILRB receptors
- (2012) Kiave-Yune HoWangYin et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Alteration of HLA-F and HLA I antigen expression in the tumor is associated with survival in patients with esophageal squamous cell carcinoma
- (2012) X. Zhang et al. INTERNATIONAL JOURNAL OF CANCER
- The tumour suppressor Fhit positively regulates MHC class I expression on cancer cells
- (2012) Irene Romero et al. JOURNAL OF PATHOLOGY
- Chemotherapeutics and Radiation Stimulate MHC Class I Expression through Elevated Interferon-beta Signaling in Breast Cancer Cells
- (2012) Shan Wan et al. PLoS One
- The role of classical and non-classical HLA class I antigens in human tumors
- (2012) Juergen Bukur et al. SEMINARS IN CANCER BIOLOGY
- Type 1 Interferons and Antiviral CD8 T-Cell Responses
- (2012) Raymond M. Welsh et al. PLoS Pathogens
- HLA-E/β2 microglobulin overexpression in colorectal cancer is associated with recruitment of inhibitory immune cells and tumor progression
- (2011) Céline Bossard et al. INTERNATIONAL JOURNAL OF CANCER
- High expression of HLA-E in colorectal carcinoma is associated with a favorable prognosis
- (2011) Maria Benevolo et al. Journal of Translational Medicine
- HLA-F expression is a prognostic factor in patients with non-small-cell lung cancer
- (2011) Aifen Lin et al. LUNG CANCER
- HLA-E expression by gynecological cancers restrains tumor-infiltrating CD8+ T lymphocytes
- (2011) M. Gooden et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Expression Regulation of Major Histocompatibility Complex Class I and Class II Encoding Genes
- (2011) Peter J. van den Elsen Frontiers in Immunology
- HLA-G Expression in Human Breast Cancer: Implications for Diagnosis and Prognosis, and Effect on Allocytotoxic Lymphocyte Response After Hormone Treatment In Vitro
- (2010) Xu He et al. ANNALS OF SURGICAL ONCOLOGY
- NF- B, and not MYCN, Regulates MHC Class I and Endoplasmic Reticulum Aminopeptidases in Human Neuroblastoma Cells
- (2010) M. Forloni et al. CANCER RESEARCH
- Biology of HLA-G in cancer: a candidate molecule for therapeutic intervention?
- (2010) Laurence Amiot et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Immunobiological Characterization of Cancer Stem Cells Isolated from Glioblastoma Patients
- (2010) T. Di Tomaso et al. CLINICAL CANCER RESEARCH
- HLA-F is a surface marker on activated lymphocytes
- (2010) Ni Lee et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Frequent loss of heterozygosity in the β2-microglobulin region of chromosome 15 in primary human tumors
- (2010) Isabel Maleno et al. IMMUNOGENETICS
- T cell recognition of HLA-A2 restricted tumor antigens is impaired by the oncogene HER2
- (2010) Kousaku Mimura et al. INTERNATIONAL JOURNAL OF CANCER
- HLA-E and HLA-G Expression in Classical HLA Class I-Negative Tumors Is of Prognostic Value for Clinical Outcome of Early Breast Cancer Patients
- (2010) E. M. de Kruijf et al. JOURNAL OF IMMUNOLOGY
- Increased Lysis of Stem Cells but Not Their Differentiated Cells by Natural Killer Cells; De-Differentiation or Reprogramming Activates NK Cells
- (2010) Han-Ching Tseng et al. PLoS One
- Soluble plasma HLA peptidome as a potential source for cancer biomarkers
- (2010) M. Bassani-Sternberg et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- NLR family member NLRC5 is a transcriptional regulator of MHC class I genes
- (2010) T. B. Meissner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ER stress affects processing of MHC class I-associated peptides
- (2009) Diana P Granados et al. BMC IMMUNOLOGY
- Cross-regulation of Signaling Pathways by Interferon-γ: Implications for Immune Responses and Autoimmune Diseases
- (2009) Xiaoyu Hu et al. IMMUNITY
- Natural killer cells kill human melanoma cells with characteristics of cancer stem cells
- (2009) G. Pietra et al. INTERNATIONAL IMMUNOLOGY
- The nonpolymorphic MHC Qa-1bmediates CD8+T cell surveillance of antigen-processing defects
- (2009) Cláudia C. Oliveira et al. JOURNAL OF EXPERIMENTAL MEDICINE
- NK Cells Recognize and Kill Human Glioblastoma Cells with Stem Cell-Like Properties
- (2009) R. Castriconi et al. JOURNAL OF IMMUNOLOGY
- Correlation of Human Leukocyte Antigen-G (HLA-G) Expression and Disease Progression in Epithelial Ovarian Cancer
- (2009) Yong Wook Jung et al. Reproductive Sciences
- Downregulation of HLA Class I molecules in the tumour is associated with a poor prognosis in patients with oesophageal squamous cell carcinoma
- (2008) Y Mizukami et al. BRITISH JOURNAL OF CANCER
- HER-2/neu mediated down-regulation of MHC class I antigen processing prevents CTL-mediated tumor recognition upon DNA vaccination in HLA-A2 transgenic mice
- (2008) Simona Vertuani et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Demethylating agent 5-aza-2′-deoxycytidine activates HLA-G expression in human leukemia cell lines
- (2008) K. Poláková et al. LEUKEMIA RESEARCH
- Structural basis for NKG2A/CD94 recognition of HLA-E
- (2008) B. K. Kaiser et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- HLA-G: from biology to clinical benefits
- (2008) Edgardo D. Carosella et al. TRENDS IN IMMUNOLOGY
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