标题
Treatment of type 2 diabetes: challenges, hopes, and anticipated successes
作者
关键词
-
出版物
Lancet Diabetes & Endocrinology
Volume 9, Issue 8, Pages 525-544
出版商
Elsevier BV
发表日期
2021-06-26
DOI
10.1016/s2213-8587(21)00113-3
参考文献
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- TAK-875 versus placebo or glimepiride in type 2 diabetes mellitus: a phase 2, randomised, double-blind, placebo-controlled trial
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- Comparable early changes in gastrointestinal hormones after sleeve gastrectomy and Roux-En-Y gastric bypass surgery for morbidly obese type 2 diabetic subjects
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- Polyomic profiling reveals significant hepatic metabolic alterations in glucagon-receptor (GCGR) knockout mice: implications on anti-glucagon therapies for diabetes
- (2011) Jianxin Yang et al. BMC GENOMICS
- Increased Whole-Body and Sustained Liver Cortisol Regeneration by 11β-Hydroxysteroid Dehydrogenase Type 1 in Obese Men With Type 2 Diabetes Provides a Target for Enzyme Inhibition
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- GIP Does Not Potentiate the Antidiabetic Effects of GLP-1 in Hyperglycemic Patients With Type 2 Diabetes
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- Effects of MK-0941, a Novel Glucokinase Activator, on Glycemic Control in Insulin-Treated Patients With Type 2 Diabetes
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- Changes in Glucose Homeostasis after Roux-en-Y Gastric Bypass Surgery for Obesity at Day Three, Two Months, and One Year after Surgery: Role of Gut Peptides
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- Management of type 2 diabetes: new and future developments in treatment
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- Novel Small Molecule Glucagon-Like Peptide-1 Receptor Agonist Stimulates Insulin Secretion in Rodents and From Human Islets
- (2010) K. W. Sloop et al. DIABETES
- The 11- -Hydroxysteroid Dehydrogenase Type 1 Inhibitor INCB13739 Improves Hyperglycemia in Patients With Type 2 Diabetes Inadequately Controlled by Metformin Monotherapy
- (2010) J. Rosenstock et al. DIABETES CARE
- 11β-Hydroxysteroid dehydrogenase type 1 inhibition in type 2 diabetes mellitus
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- Subcutaneous oxyntomodulin analogue administration reduces body weight in lean and obese rodents
- (2010) Y-L Liu et al. INTERNATIONAL JOURNAL OF OBESITY
- Piragliatin (RO4389620), a Novel Glucokinase Activator, Lowers Plasma Glucose Both in the Postabsorptive State and after a Glucose Challenge in Patients with Type 2 Diabetes Mellitus: A Mechanistic Study
- (2010) Riccardo C. Bonadonna et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Evaluation of the Glycometabolic Effects of Ranolazine in Patients With and Without Diabetes Mellitus in the MERLIN-TIMI 36 Randomized Controlled Trial
- (2009) David A. Morrow et al. CIRCULATION
- Imatinib Mesylate Reduces Endoplasmic Reticulum Stress and Induces Remission of Diabetes in db/db Mice
- (2009) M. S. Han et al. DIABETES
- GPR119 Is Essential for Oleoylethanolamide-Induced Glucagon-Like Peptide-1 Secretion From the Intestinal Enteroendocrine L-Cell
- (2009) L. M. Lauffer et al. DIABETES
- A selective small molecule glucagon-like peptide-1 secretagogue acting via depolarization-coupled Ca2+ influx
- (2009) Jun-ichi Eiki et al. JOURNAL OF ENDOCRINOLOGY
- Assessing the potential of glucokinase activators in diabetes therapy
- (2009) Franz M. Matschinsky NATURE REVIEWS DRUG DISCOVERY
- Adiponectin in health and disease: evaluation of adiponectin-targeted drug development strategies
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- Fibroblast Growth Factor 21 Reverses Hepatic Steatosis, Increases Energy Expenditure, and Improves Insulin Sensitivity in Diet-Induced Obese Mice
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